A Game-Changer for Diabetes: Polymer Delivers Insulin Painlessly Through Skin
November 25, 2025
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Brand Name :
Retrovir
(United States) [Available]Synonyms :
zidovudine
Class :
Antiviral agents and Anti-HIV (antiretroviral)
Brand Name :
Retrovir
(United States) [Available]Synonyms :
zidovudine
Class :
Antiviral agents and Anti-HIV (antiretroviral)
Dosage Forms & Strengths
Capsule, Oral:
100 mg
Solution, Intravenous:
10 mg/ml
Syrup, Oral:
10 mg/ml
Tablet, Oral:
300 mg
Note: IV therapy may not recommend until patients respond to oral therapy.
Dosage Forms & Strengths
Capsule, Oral:
100 mg
Solution, Intravenous:
10 mg/ml
Syrup, Oral:
10 mg/ml
Tablet, Oral:
300 mg
Note: IV therapy may not recommend until patients respond to oral therapy.
Ritonavir may reduce the therapeutic effects of Zidovudine, avoid combination
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
May increase plasma concentration and therapeutic effects of other antiretroviral drugs
May increase plasma concentration and therapeutic effects of other antiretroviral drugs
Zidovudine increases the serum concentrations of pantoprazole, dose adjustments may be suggested to avoid toxicity
May decrease the serum concentration of raltegravir, avoid coadministration
May enhance the therapeutic concentration of Zidovudine
Coadministration of Zidovudine with warfarin can increase the risk of bleeding or unusual bleeding
interferons may enhance the adverse/toxic effect of zidovudine
zidovudine: they may enhance the neutropenic effect of trimethoprim
When zidovudine is used together with ouabain, this leads to reduction in zidovudine excretion
terfenadine decreases the metabolism of zidovudine when used in combination
hepatitis A vaccine inactivatedÂ
combining zidovudine with the Hepatitis A Vaccine may reduce its therapeutic efficacy
the risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can increase when zidovudine is combined with alendronic acid
the metabolism of mycophenolic acid may be increased when combined with zidovudine
caffeic acid when combined with zidovudine results in more adverse effects
the threat or acuteness of adverse effects can be heightened when zidovudine is combined with stepronin
when thiotepa and zidovudine combine, the toxicity of both drugs increases by synergism
when both the drugs are combined, the risk or severity of adverse effects increases    
when both drugs are combined, there may be an increased risk or severity of adverse effects 
may diminish the serum concentration
may increase the toxic effect
may increase the toxic effect
may increase the adverse effect when combined with zidovudine
may increase the adverse effect when combined with zidovudine
may increase the myopathic effect of each other when combined
combining zidovudine with carbimazole may increase the risk or severity of myoglobinuria, myopathy, or rhabdomyolysis
may have a decrease in excretion when combined with zidovudin
imidazole salicylate and zidovudine together may make bleeding more likely
concentration of zidovudine in plasma is raised when combined with inosine acedoben dimepranol
the activity of the anthrax vaccine can be reduced when used in combination with zidovudine
Frequency defined:
>10%
Skin rash
Increased serum cholesterol
1% to 10%:
Angina pectoris
Facial edema
Myocardial infarction
Syncope
Peripheral neuropathy
Abnormal dreams
Anxiety
Confusion
Drowsiness
Disorientation
Disturbance in attention
Nervousness
Hypoesthesia
Prurigo
Night sweats
Xeroderma
Diabetes
lipohypertrophy
pancreatitis
stomatitis
anorexia
flatulence
gastritis
Post-marketing:
Angioedema
Erythema multiforme
Hemorrhagic stroke
Rhabdomyolysis
Stevens-Johnson syndrome
Dress syndrome
Pregnancy consideration: Zidovudine may be used for antiretroviral therapy in pregnant patients. Consider dose reduction to avoid hematologic toxicity.
Lactation: Zidovudine can be present in breast milk.Â
Pregnancy category:
Patient information leaflet
Generic Name: Zidovudine
Pronunciation: Zidovudine
Why do we use Zidovudine?
It is used to treat viral infections such as HIV infection.
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