Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Hypoca, Barnix, Libradin
Synonyms :
barnidipine
Class :
Calcium Channel Blocker, Dihydropyridine
Dosage Forms & StrengthsÂ
Capsule (Extended Release)Â Â
5 mgÂ
10 mgÂ
15 mg Â
20 mgÂ
Take a dose of 5 to 20 mg orally one time in a day
Take a maintenance dose of 10 to 20 mg one time in a day
Not determined Â
Refer to adult dosingÂ
barnidipine: they may enhance the serum concentration of CYP3A Inhibitors
barnidipine: they may enhance the serum concentration of CYP3A Inhibitors
barnidipine: they may enhance the serum concentration of CYP3A Inhibitors
barnidipine: they may enhance the serum concentration of CYP3A Inhibitors
barnidipine: they may enhance the serum concentration of CYP3A Inhibitors
abametapir: it may increase the serum concentration of barnidipine
abemaciclib: it may decrease the metabolism of barnidipine
abiraterone: it may decrease the metabolism of barnidipine
acalabrutinib: it may decrease the metabolism of barnidipine
acarbose: it may increase the risk of hypoglycemia with barnidipine
bedaquiline: it may decrease the metabolism of barnidipine
belumosudil: it may decrease the metabolism of barnidipine
benazepril: it may increase the antihypertensive activities of barnidipine
benorilate: it may increase the risk of hyperkalemia with barnidipine
benoxaprofen: it may increase the risk of hyperkalemia with barnidipine
calfactant: it may increase the bradycardic activities of barnidipine
canagliflozin: it may decrease the metabolism of barnidipine
Actions and SpectrumÂ
barnidipine targets L-type calcium channels in the cell membranes of smooth muscle cells in blood vessels and in cardiac muscle cells. By blocking these calcium channels, it inhibits the influx of calcium ions into these cells.
Frequency not defined Â
None
Black Box WarningÂ
NoneÂ
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
barnidipine affects cardiac muscle cells by reducing the entry of calcium ions into these cells. This results in decreased contractility of the heart muscle, which can be beneficial in certain cardiac conditions.Â
PharmacodynamicsÂ
Vasodilation leads to a decrease in peripheral vascular resistance, which is the resistance blood encounters as it flows through the arteries.Â
Reduced peripheral resistance results in a lower systemic blood pressure. The overall effect of vasodilation in the systemic circulation helps lower blood pressure.Â
PharmacokineticsÂ
Absorption  Â
barnidipine is absorbed from the gastrointestinal tract after oral administration.Â
DistributionÂ
barnidipine is distributed throughout the body.Â
MetabolismÂ
barnidipine undergoes hepatic metabolism in the liver.Â
Elimination and excretionÂ
barnidipine occurs primarily through the renal and fecal routes.Â
AdministrationÂ
barnidipine is administered orally in the form of tablets or capsules.Â
Patient information leafletÂ
Generic Name: barnidipineÂ
Why do we use barnidipine?Â
barnidipine is used in the treatment of high blood pressure i.e., for hypertension.Â
barnidipine helps relaxing the blood vessel walls, leading to vasodilation and a decrease in peripheral vascular resistance.Â
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