Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Brand Name :
No Data Available.
Synonyms :
capreomycin
Class :
Antibiotics & Aminoglycoside
Dosage forms & Strengths:Â
Powder for injectionÂ
1g/vialÂ
Dosage forms & Strengths:Â
Powder for injectionÂ
1g/vialÂ
Refer to adult dosingÂ
the excretion rate of capreomycin may be decreased by oxybenzone
capreomycin may reduce the therapeutic effects of estetrol
furosemide may enhance the ototoxic adverse effects of capreomycin
levoketoconazole may increase the therapeutic effects of capreomycin
interaction of capreomycin with medication or fluid that causes electrolyte abnormalities may lead to adverse effects such as arrhythmias, seizures, and renal impairment
interaction of capreomycin with medication or fluid that causes electrolyte abnormalities may lead to adverse effects such as arrhythmias, seizures, and renal impairment
capreomycin may reduce the therapeutic effects of the cholera vaccine
voclosporin may enhance the chances of nephrotoxicity
capreomycin may enhance the anticoagulant effects of warfarin
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
it increases the effect of neuromuscular blockage of neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with colistimethate
it increases the effect of neuromuscular blockage of aminoglycosides
neomycin/polymyxin B/bacitracin topical
it increases the effect of neuromuscular blockage of aminoglycosides
it increases the effect of neuromuscular blockage of aminoglycosides
it increases the effect of neuromuscular blockage of aminoglycosides
it increases the effect of neuromuscular blockage of aminoglycosides
tinidazole has the potential to reduce the rate of excretion of capreomycin, potentially leading to an elevation in level of serum
cefpirome leads to a reduction in the rate of excretion of capreomycin which leads to increased level of serum
capreomycin: it may increase the risk of gastrointestinal bleeding with risedronic acid
capreomycin: it may decrease the excretion rate of metheglobinemia associated agents
capreomycin: it may decrease the excretion rate of metheglobinemia associated agents
capreomycin: it may decrease the excretion rate of metheglobinemia associated agents
capreomycin: it may decrease the excretion rate of metheglobinemia associated agents
capreomycin: it may decrease the excretion rate of metheglobinemia associated agents
capreomycin: it may increase the risk of methemoglobinemia with pheneticillin
capreomycin's excretion rate may be lowered by almasilate, resulting in increased serum levels
May increase the neuro-muscular-blocking effect of aminoglycoside antibiotics
May increase the neuro-muscular-blocking effect of aminoglycoside antibiotics
may increase the neuromuscular-blocking effect
the excretory rate of capreomycin may be reduced, resulting in increased levels of serum, when combined with kebuzone
the excretory rate of capreomycin may be reduced when taken with mofebutazone, which results in increased serum levels of capreomycin
Capreomycin binds to the 70S ribosomal unit and prevents the synthesis of proteins. Â
It also binds to elements within the bacterial cell that cause aberrant proteins to be produced.Â
The survival of the bacteria depends on these proteins. The bacterial synthesis of these aberrant proteins is eventually deadly.Â
Frequency not defined:Â
AnorexiaÂ
DiarrheaÂ
DyspneaÂ
EdemaÂ
RashÂ
TinnitusÂ
ThrombocytopeniaÂ
TremorÂ
VertigoÂ
WeaknessÂ
AgranulocytosisÂ
Elevated BUNÂ
EnterocolitisÂ
HeadacheÂ
Incr salivationÂ
Muscle crampsÂ
Muscle weaknessÂ
NauseaÂ
NephrotoxicityÂ
NeurotoxicityÂ
OtotoxicityÂ
PruritusÂ
Pseudotumor cerebriÂ
Â
Capreomycin use has been linked to poor clinical results for pulmonary multidrug-resistant tuberculosis (MDR-TB) as compared to other parenteral therapies.Â
Capreomycin should be saved for patients with MDR-TB who have few other therapy choices and are resistant to IV aminoglycosides.Â
It is not advised to take capreomycin and other IV antituberculosis medications at the same time.Â
If taken with other nephrotoxic or ototoxic medications, patient should proceed with extra caution.Â
Contraindication:Â
HypersensitivityÂ
PregnancyÂ
Caution:Â
Renal impairmentÂ
History of allergic reactionsÂ
Risk of hypokalemiaÂ
Before starting treatment and at regular intervals throughout it, vestibular function evaluation and audiometric assessments should be conducted.Â
Pregnancy considerations: Capreomycin has been assigned under category C.Â
Lactation: Excretion of capreomycin during lactation is not known. Â
Pregnancy category:Â
The antibiotics of the aminoglycoside family include capreomycin.Â
These antibiotics can eliminate a broad range of microorganisms, including those causes tuberculosis.Â
Four components that are microbiologically active make up the polypeptide antibiotic complex.Â
Prepare the IV by diluting the reconstituted solution in 100 ml of 0.9% NaCl.Â
IM Administration:Â
As superficial injections may result in sterile abscesses and increased pain, administer by deep intramuscular injection into a big muscle mass.Â
IV AdministrationÂ
The IV dose should be infused over 60 minutes.Â
Generic Name: capreomycinÂ
Why do we use capreomycin? Â
Capreomycin is indicated in pulmonary infections caused due to capreomycin-susceptible strains of M. tuberculosis.Â
It is indicated when primary agents are ineffective or cannot be used due to toxicity or presence of resistant tubercle bacilli.Â