Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
ceftin
(United States) [Available] ,Zinacef
(United States) [Available]Synonyms :
Class :
Antibiotics & Cephalosporins (second generation)
Brand Name :
ceftin
(United States) [Available] ,Zinacef
(United States) [Available]Synonyms :
Class :
Antibiotics & Cephalosporins (second generation)
Dosage forms & StrengthsÂ
Suspension, Oral:Â
125 mg (5 ml)Â
250 mg (5 ml)Â
Solution reconstituted, IV,IM:Â
750 mgÂ
1.5 mgÂ
7.5 mgÂ
75 mgÂ
22 mg Â
Tablet, Oral:Â
250 mgÂ
500 mgÂ
Note: Oral suspensions of cefuroxime such as ceftin has been discontinued in the US. Â
Wound infection (animal or human):Â
500 mg oral b.i.s in combination with other beta-lactamase inhibitors for 5 to 14 days (duration of therapy based on the clinical response)Â Â Â
Chronic obstructive pulmonary disease (COPD):Â Â
500 mg oral b.i.s for 5 to 7 days  Â
Acute Cholecystitis, perforated appendix, diverticulitis, and other intra-abdominal infections:Â
1.5 g IV every 8 hours in combination with metronidazole for 5 to 10 days;Â
For uncomplicated appendicitis, the duration is 7 to 10 days Â
Lyme disease:Â
500 mg oral b.i.s for 14 days Â
Acute otitis media:Â
500 mg oral b.i.s for 5 to 7 days (for severe infections 10 days)Â Â Â
Pneumonia:Â
500 mg oral b.i.s in combination with other antibiotics for 5 days Â
Pharyngitis:Â
250 mg oral b.i.s for 10 days Â
Surgical prophylaxis:Â
1.5 g IV in combination with metronidazole within 60 minutes prior to surgeryÂ
(Repeat the dose in 4 hours for lengthy surgery)Â Â
Urinary tract infection:Â
250 mg b.i.s daily for 5 to 7 days Â
Dose adjustments:Â
Dose adjustments for oral route:Â
Dose adjustment for IV route:Â
Â
Dosage forms & StrengthsÂ
Suspension, Oral:Â
125 mg (5 ml)Â
250 mg (5 ml)Â Â
Solution reconstituted, IV, IM:Â
750 mgÂ
1.5 mgÂ
7.5 mgÂ
75 mgÂ
22 mg  Â
Tablet, Oral:Â
250 mgÂ
500 mgÂ
Note: Ceftin (oral suspension) has been discontinued in the US. Â
General dosing for infants, children, and adolescents:Â Â
Mild to moderate infection:Â
20 to 30 mg/kg oral divided twice a day (do not exceed 500mg/dose)Â
75 to 100 mg/kg IV/IM split into three doses (do not exceed 1500mg/dose)Â
100 to 200 mg/kg IV/IM split into 3 or 4 doses for severe infections (do not exceed 1500mg/dose)Â Â
Bone & joint infection:Â
50 mg/kg IV/IM per dose q8H (do not exceed 1,500 mg/dose), follow up with antibiotic dose if indicated Â
Bronchitis:Â
250 mg to 500 mg oral tablet q12H continued for 10 days Â
Impetigo:Â
15 mg/kg oral suspension twice a day for 10 days (do not exceed 500mg/dose)Â Â Â
Pharyngitis:Â
10 mg/kg oral suspension twice a day (do not exceed 250mg/dose)Â Â
Intra-abdominal infection:Â
4500 mg IV per day divided equally for a single dose administered every 6 hours (do not exceed 1500mg/dose)Â Â
Sinusitis:Â
For infants >3 months and children: 15 mg/kg oral suspension twice a day for 10 days (do not exceed 500 mg/dose)Â
Adolescents: 250 to 500 mg oral tablet twice a day for 10 days Â
Skin and skin structure infections:Â
250 to 500 mg oral tablet twice a day for 10 days Â
Surgical prophylaxis:Â
50 mg/kg within 60 minutes prior to proceeding for surgery, repeat the dose in 4 hours for lengthy or complicated surgeryÂ
Â
Refer to adult dosingÂ
cefuroxime: they may diminish the serum concentration of antacids
cefuroxime: they may diminish the serum concentration of antacids
cefuroxime: they may diminish the serum concentration of antacids
cefuroxime: they may diminish the serum concentration of antacids
cefuroxime: they may diminish the serum concentration of antacids
cefuroxime: they may diminish the serum concentration of magnesium salts
cefuroxime: they may diminish the serum concentration of magnesium salts
cefuroxime: they may diminish the serum concentration of magnesium salts
cefuroxime: they may diminish the serum concentration of magnesium salts
cefuroxime: they may diminish the serum concentration of magnesium salts
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
the interaction decreases the therapeutic effects of the vaccine
the interaction decreases the therapeutic effects of the vaccine
the interaction decreases the therapeutic effects of the vaccine
bazedoxifene conjugated estrogens
cefuroxime may reduce the therapeutic effects of oral forms of conjugated estrogen by altering gut microflora
cefuroxime will reduce the therapeutic effects of oral forms of hormones by altering gut microflora
cefuroxime will reduce the therapeutic effects of oral forms of hormones by altering gut microflora
furosemide may enhance the therapeutic effects of cefuroxime
the interaction may increase the therapeutic effects of cefuroxime
the interaction may increase the therapeutic effects of cefuroxime
cefuroxime reduces the therapeutic effects of sodium picosulfate by altering metabolism
cephalosporins may decrease serum concentration and enhance nephrotoxicity of aminoglycosides
enhance the serum drug concentration by reducing renal clearance
enhance the serum drug concentration by reducing renal clearance
may raise the risk of nephrotoxicity
cefuroxime increases the anticoagulant activity of warfarin by an unknown mechanism
may increase the nephrotoxic effect of aminoglycosides
may increase the nephrotoxic effect of aminoglycosides
may increase the nephrotoxic effect of aminoglycosides
may increase the nephrotoxic effect of aminoglycosides
may increase the nephrotoxic effect of aminoglycosides
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
When cefuroxime is used together with piroxicam, this leads to increased risk or seriousness of nephrotoxicity
When cefmenoxime is used together with cefuroxime, this leads to enhanced risk or seriousness of nephrotoxicity
When cefuroxime is used together with proglumetacin, this leads to enhanced risk or seriousness of nephrotoxicity
may have an increased nephrotoxic effect when combined with aminoglycosides
neomycin/polymyxin B/bacitracin topical
may have an increased nephrotoxic effect when combined with aminoglycosides
When cefuroxime is used together with benoxaprofen, this leads to enhanced risk or seriousness of nephrotoxicity
cefuroxime leads to a reduction in the rate of excretion of eucalyptus oil which leads to increased level of serum
When cefuroxime is used together with aluminium phosphate, this leads to a reduction in the concentration serum of cefuroxime
When cefuroxime is used together with bismuth subnitrate, this leads to a reduction in the concentration serum of cefuroxime
cefuroxime leads to a reduction in the rate of excretion of pentaerythritol tetranitrate, which leads to an increased level of serum
cefuroxime leads to a reduction in the rate of excretion of potassium acetate, which leads to an increased level of serum
cefuroxime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
When cefuroxime is used together with difenpiramide, this leads to enhanced risk or seriousness of nephrotoxicity
cefuroxime's serum concentration may be reduced when it is combined with almasilate
When both drugs are combined, there may be an increased risk or severity of adverse effects  
demeclocycline reduces the effects of bactericidal agents
doxycycline reduces the effects of bactericidal agents
may increase the nephrotoxic effect of cephalosporins
neomycin/polymyxin B/bacitracin topical
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the anticoagulant effect of cephalosporins
may increase the anticoagulant effect of cephalosporins
may increase the anticoagulant effect of cephalosporins
may increase the anticoagulant effect of cephalosporins
may increase the anticoagulant effect of cephalosporins
the excretory rate of cefuroxime may be reduced when taken with mofebutazone, resulting in increased serum levels of cefuroxime
cefuroxime might lead to a reduction in the rate of excretion of telavancin, potentially leading to elevated levels of serum
cefuroxime increases the serum concentration of other drugs by reducing renal clearance
cefuroxime increases the serum concentration of other drugs by reducing renal clearance
cefuroxime increases the serum concentration of other drugs by reducing renal clearance
the interaction reduces the effects of cefuroxime
cefuroxime increases the therapeutic effects of cyclopenthiazide
cefuroxime increases the serum concentration of other drugs by reducing renal clearance
cefuroxime will increase the effects of sulfasalazine
Frequency defined:Â Â
1-10%Â
Diarrhea (3%)Â
Nausea (2%)Â
Vomiting (7%)Â
Headache (1%)Â
Fever Â
Pruritis localized (1%)Â
Skin rash (1%)Â
Increase serum aspartate aminotransferase (2%)Â
Eosinophilia (3%)Â
Jarisch-herxheimer reaction (6%)Â
Â
<1%:Â
Chest painÂ
Increased thirstÂ
Abdominal painÂ
Local painÂ
Local inflammationÂ
VaginitisÂ
UrticariaÂ
Increased serum bilirubinÂ
Increased serum creatinineÂ
Anemia   Â
Postmarketing: (rare )Â
Status epilepticusÂ
ComaÂ
HallucinationÂ
confusionÂ
Pregnancy consideration: Cefuroxime is assigned under pregnancy category A. cefuroxime can be considered for the treatment of maternal infection.Â
Lactation: Cefuroxime can be excreted in breast milk. Monitor infants for GI disturbances such as diarrhea or thrush. Â
Pregnancy category:Â
Patient information leafletÂ
Generic Name: CefuroximeÂ
Pronounced: ce· fur· o· ximeÂ
Â
Why do we use cefuroxime?Â
Cefuroxime is a second-generation cephalosporin antibiotic drug. It is used to treat bacterial infections such as lung, skin, urinary tract, and kidney infections. It kills bacteria by inhibiting bacterial cell wall synthesis. Â
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