Fame and Mortality: Evidence from a Retrospective Analysis of Singers
November 26, 2025
Brand Name :
Guanidine hydrochloride
Synonyms :
guanidine
Class :
Cholinergic agents
Dosage Forms & StrengthsÂ
TabletÂ
125mgÂ
Lambert-Eaton Myasthenic SyndromeÂ
10 - 15
mg/kg
Tablet
Orally 
divided into 3-4 doses
Increase upto 35mg/kg
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may increase the toxic effect
may decrease the anticholinergic effect
may have a decrease in excretion when combined with guanidine
Frequency not defined:Â Â
AnemiaÂ
ThrombocytopeniaÂ
RashÂ
Dry mouthÂ
FolliculitisÂ
UremiaÂ
Abnormal liver function testÂ
Skin eruptionsÂ
PurpuraÂ
Renal tubular necrosisÂ
HypotensionÂ
AnorexiaÂ
Abdominal crampingÂ
TremorÂ
ConfusionÂ
Pregnancy consideration: Insufficient data availableÂ
Lactation: The drug is excreted in the human breast milk Â
Pregnancy category:Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.  Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this categoryÂ
Patient information leafletÂ
Generic Name: guanidineÂ
Pronounced: (gua·​ni·​dine)Â
Why do we use guanidine?Â
It is used to treat myasthenia gravis (muscle weakness)Â