Microplastics and Misinformation: What Science Really Says
November 12, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Mestinon
(United States) [Available] ,Regonol
(United States) [Available]Synonyms :
Class :
Acetylcholinesterase and reversible anticholinesterases
Brand Name :
Mestinon
(United States) [Available] ,Regonol
(United States) [Available]Synonyms :
Class :
Acetylcholinesterase and reversible anticholinesterases
Dosage Forms & Strengths Â
Solution-Oral Â
60 mg/5 ml Â
Tablet-Oral Â
30 mg, 60 mg Â
Tablet ER Â
180 mg Â
600
mg
Tablet
Orally 
once a day
or 180-540 mg tablet ER orally once a day
600
mg
Tablet
Orally 
once a day
or 180-540 mg tablet ER orally once a day
Reversal Of Nondepolarizing Muscle Relaxants
0.1 - 0.25
mg/kg
Orally 
once a day
for full recovery 10-20 mg is very effective
To prevent side effects a dose of 0.6-1.2 mg IV atropine sulfate given immediately before pyridostigmine
Reversal Of Nondepolarizing Muscle Relaxants
0.1 - 0.25
mg/kg
Orally 
once a day
for full recovery 10-20 mg is very effective
To prevent side effects a dose of 0.6-1.2 mg IV atropine sulfate given immediately before pyridostigmine
30
mg
Tablet
Orally 
3 times a day
initial starting at several hours before to exposure
Dosage Forms & Strengths  Â
Solution-Oral  Â
60 mg/5 ml  Â
Tablet-Oral  Â
30 mg, 60 mg  Â
Tablet ER  Â
180 mg  Â
Age: children
7 mg/kg tablet orally 4 times a day
0.05-0.15 mg/kg solution IV/IM 4times a day
Age: Newborn:
5 mg tablet orally 4times a day
0.05-0.15 mg/kg IV/IM 4 times a day
Reversal Of Nondepolarizing Muscle Relaxants
0.1 - o.2
mg/kg
Intravenous (IV)
once a day
for full recovery 0.1-0.25 mg/kg/dose is very effective
Reversal Of Nondepolarizing Muscle Relaxants
0.1 - o.2
mg/kg
Intravenous (IV)
once a day
for full recovery 0.1-0.25 mg/kg/dose is very effective
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the neurotoxic effect
may increase the bradycardic effect
may increase the bradycardic effect
may increase the bradycardic effect
may increase the bradycardic effect
may increase the bradycardic effect
may increase the bradycardic effect
may increase the bradycardic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
It may enhance the risk of adverse effects when combined with anticholinesterases
May diminish the therapeutic effect of Anticholinergic Agents
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the risk of adverse effect of acetylcholinesterase inhibitors
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the risk of adverse effect
may enhance the risk of adverse effect
may enhance the risk of adverse effect
may enhance the risk of adverse effect
may enhance the risk of adverse effect
may decrease the therapeutic effect of Acetylcholinesterase Inhibitors
It may enhance the risk of adverse effects when combined with hormone antagonists
When pyridostigmine is used together in combination with profenamine, this leads to reduction in therapeutic effectiveness of profenamine
Adverse drug reactions: Â
Frequency Not Defined Â
ECG changes Â
Loss of consciousness Â
Convulsions Â
Drowsiness Â
Thrombophlebitis Â
Urticaria Â
Hypotension Â
Arrhythmia Â
Laryngospasm Â
Bradycardia  Â
Pregnancy warnings:   Â
Pregnancy Category: BÂ
Breastfeeding warnings:Â
The release of the drug into the human breastmilk is unknown Â
Pregnancy Categories:     Â
Patient Information Leaflet Â
Generic Name: pyridostigmineÂ
Pronounciation: py-rid-o-STIG-meenÂ
Why do we use pyridostigmine?Â
pyridostigmine belongs to the class Cholinergic muscle stimulants used to treat myasthenia gravis and helps in reversal of nondepolarizing muscle relaxantsÂ
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
