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Brand Name :
Alpha-Lipoic-Acid-300, Alpha Lipoic Acid, Alpha Lipoic
Synonyms :
alpha-lipoic acid
Class :
Nutraceutical products
Brand Name :
Alpha-Lipoic-Acid-300, Alpha Lipoic Acid, Alpha Lipoic
Synonyms :
alpha-lipoic acid
Class :
Nutraceutical products
Dosage Forms & Strengths
Capsule/Tablet
600 mg
300 mg
100 mg
200 mg
50 mg
300 mg of capsule taken orally one to two times a day or 50 mg of tablet taken orally once a day with the meal
Safety & efficacy were not established
Refer to the adult dosing regimen
may have a decreased absorption when combined with alpha-lipoic acid
may have a decreased absorption when combined with alpha-lipoic acid
may have a decreased absorption when combined with alpha-lipoic acid
may have a decreased absorption when combined with alpha-lipoic acid
may have a decreased absorption when combined with alpha-lipoic acid
may diminish the absorption when combined with alpha-lipoic acid
may diminish the absorption when combined with alpha-lipoic acid
may diminish the absorption when combined with alpha-lipoic acid
may diminish the absorption when combined with alpha-lipoic acid
may have an increased risk of hypoglycemia when combined with acarbose
may have an increased risk of hypoglycemia when combined with acetohexamide
may have an increased risk of hypoglycemia when combined with albiglutide
may have an increased risk of hypoglycemia when combined with bromocriptine
may have an increased risk of hypoglycemia when combined with chlorpropamide
Alpha-Lipoic Acid: they may diminish the absorption of antacids
Alpha-Lipoic Acid: they may diminish the absorption of antacids
Alpha-Lipoic Acid: they may diminish the absorption of antacids
Alpha-Lipoic Acid: they may diminish the absorption of antacids
Alpha-Lipoic Acid: they may diminish the absorption of antacids
may diminish the absorption of iron preparations
may enhance the serum concentration of magnesium salts
may diminish the absorption of Alpha-Lipoic Acid
may have an increased risk of hypoglycemia when combined with citalopram
may have an increased risk of hypoglycemia when combined with duloxetine
may have an increased risk of hypoglycemia when combined with escitalopram
may have an increased risk of hypoglycemia when combined with fluoxetine
may have an increased risk of hypoglycemia when combined with glimepiride
it increases the effect of hypoglycemia of antidiabetic agents
it increases the effect of hypoglycemia of antidiabetic agents
it increases the effect of hypoglycemia of antidiabetic agents
it increases the effect of hypoglycemia of antidiabetic agents
it increases the effect of hypoglycemia of antidiabetic agents
alpha-lipoic acid: they may increase the hypoglycemic effect of antidiabetic drugs
alpha-lipoic acid: they may increase the hypoglycemic effect of antidiabetic drugs
alpha-lipoic acid: they may increase the hypoglycemic effect of antidiabetic drugs
may have an increased risk of hypoglycemia when combined with insulin glargine
may have an increased risk of hypoglycemia when combined with insulin human
may have an increased risk of hypoglycemia when combined with mifepristone
may have an increased risk of hypoglycemia when combined with pregabalin
may have an increased risk of hypoglycemia when combined with sulfamethoxazole
may have an increased risk of hypoglycemia when combined with sulfadiazine
may have an increased risk of hypoglycemia when combined with tolbutamide
may increase the hypoglycemic effect of Antidiabetic Agents
may increase the hypoglycemic effect of Anti-diabetic Agents
may increase the hypoglycemic effect when combined
may increase the hypoglycemic effect of Antidiabetic Agents
ferrous succinate has the potential to impair lipoic acid absorption, which could compromise efficacy by lowering serum levels
Actions and spectrum:
alpha-lipoic acid acts as a cofactor in several enzyme complexes involved in converting nutrients into energy within the mitochondria. It is a versatile antioxidant that can neutralize free radicals & regenerate other antioxidants like vitamins C and E helps to protect cells from oxidative stress and damage.
Frequency not defined
Black Box Warning:
none
Contraindication/Caution:
Contraindicated with known allergies or hypersensitivity
Pregnancy consideration: US FDA pregnancy category: Not assigned
Lactation: Excreted into human milk: unknown
Pregnancy category:
Pharmacology:
Pharmacodynamics:
alpha-lipoic acid is the potent antioxidant that helps to neutralize free radicals & reactive oxygen species by reducing oxidative stress in cells and tissues.
It protects cellular components like lipids, proteins, and DNA from oxidative damage and contributing to overall cellular health.
Pharmacokinetics:
Absorption
Well absorbed
Distribution
Distributed widely.
Metabolism
Metabolized through reduction and oxidation reactions.
Elimination and excretion
Metabolites are excreted in urine.
Administration:
Alpha-lipoic acid is available in oral tablets, capsules, and soft gels forms.
It can also be found as a component of some multivitamin and dietary supplements.
ntestinal discomfort.
Patient information leaflet
Generic Name: alpha-lipoic acid
Pronounced: (AL-fa-lie-POE-ik A-sid)
Why do we use alpha-lipoic acid?
Alpha-lipoic acid is an antioxidant that neutralizes free radicals which aids in diabetes management and manages nerve conditions by promoting skin health
It supports in weight loss, improves cognitive function, and may contribute to cardiovascular health by enhancing blood vessel function and cholesterol levels.
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