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Brand Name :
N/A
Synonyms :
amrinone
Class :
Cardiac Drugs
Brand Name :
N/A
Synonyms :
amrinone
Class :
Cardiac Drugs
Dosage Forms & Strengths
tablet
750 mcg
not indicated
refer adult dosing
may enhance the adverse/toxic effect of alprostadil
respiratory syncytial virus vaccine, adjuvanted
may diminish the pharmacodynamic antagonistic effect of each other when combined
respiratory syncytial virus (RSV) vaccine
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may enhance the hypotensive effect of Blood Pressure Lowering Agents
may enhance the hypotensive effect of Blood Pressure Lowering Agents
may enhance the hypotensive effect of Blood Pressure Lowering Agents
may enhance the hypotensive effect of Blood Pressure Lowering Agents
may enhance the hypotensive effect of Blood Pressure Lowering Agents
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
bunazosin (Not available in the United States)
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
antipyrine has the potential to reduce the rate of excretion of amrinone, potentially leading to an elevation in the serum concentration
amrinone has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
It may enhance the risk of adverse effects when combined with Platelets inhibitors
It may enhance the risk of adverse effects when combined with Platelets inhibitors
It may enhance the risk of adverse effects when combined with Platelets inhibitors
It may enhance the risk of adverse effects when combined with Platelets inhibitors
It may enhance the risk of adverse effects when combined with Platelets inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet Inhibitors
dexchlorpheniramine, dextromethorphan, and phenylephrine
It may enhance the risk of adverse effects when combined with platelet Inhibitors
It may enhance the risk of adverse effects when combined with platelet inhibitors
It may enhance the risk of adverse effects when combined with platelet inhibitors
tinidazole has the potential to reduce the rate of excretion of amrinone, potentially leading to an elevation in level of serum
fentiazac may reduce the elimination rate of amrinone, resulting in a greater serum level
amrinone leads to a reduction in the rate of excretion of eucalyptus oil which leads to increased level of serum
cefpirome leads to a reduction in the rate of excretion of amrinone which leads to increased level of serum
amrinone leads to a reduction in the rate of excretion of chromous sulfate, which leads to an increased level of serum
amrinone leads to a reduction in the rate of excretion of pentaerythritol tetranitrate, which leads to an increased level of serum
amrinone leads to a reduction in the rate of excretion of potassium acetate, which leads to an increased level of serum
amrinone leads to a reduction in the rate of excretion of potassium perchlorate, which leads to an increased level of serum
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
morniflumate may reduce the excretion rate of amrinone, potentially leading to an elevated serum level
amrinone may decrease the excretion rate of almasilate, leading to higher serum levels
sapropterin may increase the hypotensive effect of phosphodiesterase 5 inhibitors
may increase the hypotensive effect of Blood Pressure Lowering Agents
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with general anesthesia
amrinone might lead to a reduction in the rate of excretion of telavancin, potentially leading to elevated levels of serum
Actions and Spectrum:
amrinone also has vasodilatory properties, which means it relaxes and widens blood vessels. This can reduce the workload on the heart by lowering peripheral resistance and making it easier for the heart to pump blood throughout the body.
amrinone is often used in the acute care setting, such as in hospitals, for patients with severe heart failure who require immediate intervention to improve cardiac output and alleviate symptoms.
It may be used as a bridge therapy for patients awaiting heart transplantation or other long-term heart failure treatments.
amrinone is typically administered intravenously and is used for short-term management of heart failure exacerbations. It is not a long-term maintenance therapy for heart failure.
It’s important to note that amrinone is associated with potential side effects and should be used under the close supervision of healthcare professionals. Due to the availability of newer medications with similar therapeutic effects and a better safety profile, amrinone is less commonly used today than in the past. The specific use of amrinone and its dosing regimen should be determined by a healthcare provider based on the patient’s individual condition and needs.
Frequency defined
hypotension
hypersensitivity
chest pain
None
Pregnancy consideration:
US FDA pregnancy category: N/A
Lactation:Â Â
Excreted into human milk is Not known.
Pregnancy category:
Patient information leaflet
Generic Name: amrinone
Why do we use amrinone?
amrinone is a medication used to treat certain heart conditions, particularly those related to heart failure. Here are the primary reasons why amrinone is used:
amrinone is primarily used in the treatment of heart failure, a condition in which the heart is unable to pump blood effectively. It is particularly beneficial in cases of acute decompensated heart failure, where the patient’s symptoms have worsened suddenly and require immediate intervention.
It has a positive inotropic effect, meaning it increases the strength of the heart’s contractions. This can help improve cardiac output, allowing the heart to pump blood more efficiently in individuals with weakened heart muscles.
Amrinone also has vasodilatory properties, which means it relaxes and widens blood vessels. This can reduce the workload on the heart by lowering peripheral resistance, making it easier for the heart to pump blood throughout the body.
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