Microplastics and Misinformation: What Science Really Says
November 12, 2025
Brand Name :
No Data Available.
Synonyms :
dobutamine
Class :
Inotrope and Catecholamines
Dosage Forms & Strengths Â
Infusion solution Â
100, 200, 400 mg/100mL Â
Injectable solution Â
12.5mg/mL Â
Congestive Heart Failure (CHF)
Initial dose: 0.5-1 mcg/kg IV infusion over 1 minute
Maintenance dose: 2-20 mcg/kg IV infusion over 1 minute
the maximum dose recommended is 40 mcg/kg IV infusion over 1 minute
Dosage Forms & Strengths Â
Infusion solution Â
100, 200, 400 mg/100mL Â
Injectable solution Â
12.5mg/mL Â
Congestive Heart Failure (CHF)
Initial dose: 0.5-1 mcg/kg IV infusion over 1 minute
Maintenance dose: 2-20 mcg/kg IV infusion over 1 minute
the maximum dose recommended is 40 mcg/kg IV infusion over 1 minute
refer adult dosing
may increase the hypokalemic effect of thiazide diuretics
may increase the hypokalemic effect of thiazide diuretics
may decrease the therapeutic effect when combined with methacholine
May increase the adverse effect when combined
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may increase the adverse effect of other beta2-agonists
may increase the adverse effect of other beta2-agonists
may increase the toxic effect of beta2 agonists
may decrease the bronchodilatory effect when combined with beta2-agonists
may decrease the bronchodilatory effect when combined with beta2-agonists
may decrease the bronchodilatory effect when combined with beta2-agonists
may decrease the bronchodilatory effect when combined with beta2-agonists
may decrease the bronchodilatory effect when combined with beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may have an increasingly adverse effect when combined with other beta2-agonists
may decrease the therapeutic effect of each other when combined
may have an increasingly adverse effect when combined with beta2-agonists
may increase the adverse effect of other beta2-agonists
may increase the adverse effect of other beta2-agonists
beta2 agonist bronchodilation may be reduced with beta2 blockers
may decrease the bronchodilatory effect when combined with Beta2-Agonists
may decrease the bronchodilatory effect when combined with Beta2-Agonists
may decrease the bronchodilatory effect when combined with Beta2-Agonists
calcium salts reduces the efficacy of dobutamine
calcium salts reduces the efficacy of dobutamine
calcium salts reduces the efficacy of dobutamine
calcium salts reduces the efficacy of dobutamine
calcium salts reduces the efficacy of dobutamine
Beta-Blockers decrease the efficacy of dobutamine
Beta-Blockers decrease the efficacy of dobutamine
Beta-Blockers decrease the efficacy of dobutamine
Beta-Blockers decrease the efficacy of dobutamine
Beta-Blockers decrease the efficacy of dobutamine
may decrease the bronchodilatory effect of beta-blockers
may decrease the bronchodilatory effect of beta-blockers
may increase the adverse effect of monoamine oxidase inhibitors
may increase the adverse effect of monoamine oxidase inhibitors
may increase the adverse effect of monoamine oxidase inhibitors
may increase the adverse effect of monoamine oxidase inhibitors
may increase the adverse effect of monoamine oxidase inhibitors
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
dobutamine: they may decrease the therapeutic effect of Beta-Blockers
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
The therapeutic efficacy of dobutamine may be diminished when used concurrently with calcium salts
dobutamine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
may decrease the bronchodilatory effect of beta-blockers
may decrease the bronchodilatory effect of beta-blockers
may decrease the bronchodilatory effect of beta-blockers
may decrease the bronchodilatory effect of beta-blockers
may decrease the bronchodilatory effect of beta-blockers
eprosartan/hydrochlorothiazideÂ
may increase the toxic effect of thiazide and thiazide like diuretics
moexipril/hydrochlorothiazideÂ
may increase the hypokalaemia effect of thiazide and thiazide like diuretics
may enhance the risk or severity of hypertension when combined
may have an increasingly adverse effect when combined with atosiban
may have an increasingly adverse effect when combined with beta2-agonists
may have an increasingly adverse effect when combined with beta2-agonists
may have an increasingly adverse effect when combined with beta2-agonists
may have an increasingly adverse effect when combined with beta2-agonists
may have an increasingly adverse effect when combined with beta2-agonists
atomoxetine: they may increase the tachycardic effect of Beta2-Agonists
tricyclic antidepressants: they may increase the toxic effect of Beta2-Agonists
tricyclic antidepressants: they may increase the toxic effect of Beta2-Agonists
tricyclic antidepressants: they may increase the toxic effect of Beta2-Agonists
tricyclic antidepressants: they may increase the toxic effect of Beta2-Agonists
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
hypokalemic effects of thiazide-like derivatives can be increased with beta2 agonists
hypokalemic effects of thiazide-like derivatives can be increased with beta2 agonists
hypokalemic effects of thiazide-like derivatives can be increased with beta2 agonists
hypokalemic effects of thiazide-like derivatives can be increased with beta2 agonists
may diminish the bronchodilatory effect when combined with beta2-agonists
may diminish the bronchodilatory effect when combined with beta2-agonists
may diminish the bronchodilatory effect when combined with beta2-agonists
Actions and Spectrum:
Actions of Dobutamine:
Spectrum of Dobutamine: dobutamine is primarily used in the treatment of various cardiovascular conditions, including:
Adverse drug reactions: Â
Frequency Defined Â
1-10% Â
Dyspnea  Â
Fever  Â
Headache  Â
Nausea Â
Tachyarrhythmia Â
Hypertension Â
Eosinophilic myocarditis Â
Angina  Â
Palpation  Â
Frequency Not Defined Â
Hypokalemia Â
Injection-site reactions Â
Cardiac dysrhythmia Â
Exacerbation of coronary arteriosclerosis Â
 Â
Pregnancy warnings:   Â
AU TGA pregnancy category: B2
US FDA pregnancy category: BÂ
Breastfeeding warnings:Â
The release of the drug into the human breastmilk is unknown Â
Pregnancy Categories:     Â
Patient Information Leaflet Â
Generic Name: dobutamine
Why do we use dobutamine?Â
dobutamine is a medication commonly used in medical settings for its cardiovascular effects. It is primarily used in situations where there is a need to increase cardiac output, such as in cases of heart failure or during certain medical procedures.