A Milestone Moment: FDA Approves Addyi® for Hypoactive Sexual Desire Disorder in Postmenopausal Women
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Brand Name :
Halcion
Synonyms :
Class :
Hypnotics; Benzodiazepines
Dosage forms & Strengths:
Adult:
Schedule IV tablet:
0.125 mg
0.25 mg
0.125 - 0.25
mg
Tablet
Orally
at bedtime
Start with a lower dose of 0.125 mg, do not exceed more than 0.25 mg per day
Dose Adjustments
Start with a lower dose of 0.125 mg, do not exceed more than 0.25 mg per day
triazolam: they may enhance the serum concentration of CYP3A4 Inducers
triazolam: they may enhance the serum concentration of CYP3A4 Inducers
triazolam: they may enhance the serum concentration of CYP3A4 Inducers
triazolam: they may enhance the serum concentration of CYP3A4 Inducers
triazolam: they may enhance the serum concentration of CYP3A4 Inducers
The interaction may increase the risk of sedation, respiratory depression, and coma
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
the effect of triazolam is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
CYP3A strong enhancers of the small intestine may reduce the bioavailability of triazolam
may increase the serum concentration of each other when it is combined
may increase the serum concentration of each other when it is combined
may increase the serum concentration of each other when it is combined
may increase the serum concentration of each other when it is combined
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
may enhance the risk of CNS depression when combined
may enhance the serum concentration of CYP3A4 inhibitors
may enhance the serum concentration of CYP3A4 inhibitors
may enhance the serum concentration of CYP3A4 inhibitors
may enhance the serum concentration of CYP3A4 inhibitors
may enhance the serum concentration of CYP3A4 inhibitors
It may enhance the serum concentration when combined with CYP3A4 Inhibitors
It may enhance the serum concentration when combined with CYP3A4 Inhibitors
It may enhance the serum concentration when combined with CYP3A4 Inhibitors
It may enhance the serum concentration when combined with CYP3A4 Inhibitors
It may enhance the serum concentration when combined with CYP3A4 Inhibitors
triazolam: they may enhance the serum concentration of CYP3A Inhibitors
flupirtine excretion rate may be slowed by triazolam, raising the possibility of higher serum levels
triazolam: they may enhance the serum concentration of CYP2D6 Inhibitors
triazolam: they may enhance the serum concentration of CYP2D6 Inhibitors
triazolam: they may enhance the serum concentration of CYP2D6 Inhibitors
triazolam: they may enhance the serum concentration of CYP2D6 Inhibitors
triazolam: they may enhance the serum concentration of CYP2D6 Inhibitors
when taken with butobarbital, triazolam may enhance the likelihood or intensity of CNS depression
metronidazole enhances the effect of flibanserin by altering the intestinal or hepatic CYP3A4 enzyme metabolism
CNS Depressants may enhance the CNS depressant effect of thalidomide
may enhance the serum concentration of CYP3A4 inhibitors
may have an increased adverse effect when combined with olanzapine.
may enhance the serum concentration of CYP3A4 Inhibitors
the rate of excretion of inositol may be reduced
>10%:
Drowsiness
1-10%:
Headache
Dizziness
Nervousness
Ataxia
Light-headedness
<1%:
Anterogade amnesia
Paradoxical reactions
Confusion
Cramps
Visual disturbance
Anterograde amnesia
Fatigue
Memory impairment
Depression
Xerostomia
Dreaming
Nightmares
Confusion
Triazolam is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients.
Pregnancy consideration:
Benzodiazepines easily cross the placental barrier, hence may cause sedation defects in neonates
Breastfeeding warnings:
The drug is excreted in breastmilk, hence should be used with caution
Pregnancy category:
Patient information leaflet
Generic Name: triazolam
Pronounced: triah-zoh-lam
Why do we use triazolam?
Triazolam treats insomnia.