Alcohol Consumption Emerges as a Key Risk Factor for Buccal Cancer in India
December 24, 2025
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Brand Name :
Acocontin, Ambolar, Ambril, Ambroban
Synonyms :
ambroxol
Class :
Mucolytic Agent
Brand Name :
Acocontin, Ambolar, Ambril, Ambroban
Synonyms :
ambroxol
Class :
Mucolytic Agent
Dosage Forms & Strengths
Capsule (Extended Release)
75 mg
Lozenge
20 mg
Solution
7.5 mg/ml
Tablet
30 mg
Take a daily dose of 60 to 120 mg orally in 2 to 3 divided doses
Inhale a dose of 15 to 22.5 mg through nebulizer for 1 to 2 times daily
Dosage Forms & Strengths
Capsule (Extended Release)
75 mg
Lozenge
20 mg
Solution
7.5 mg/ml
Tablet
30 mg
for 2 to <6 years old:
Take a dose of 7.5 to 15 mg orally three times a day
for 6 to 12 years old:
Take a dose of 15 to 30 mg orally 2 to 3 times in a day
for >12 years old:
Take a daily dose of 60 to 120 mg orally in 2 to 3 divided doses
for <6 years old:
Inhale a dose of 15 mg through nebulizer for 1 to 2 times in a day
for ≥6 years old:
Inhale a dose of 15 to 22.5 mg through nebulizer for 1 to 2 times in a day
Refer to adult dosing
ambroxol: it may increase the risk of methemoglobinemia agents
ambroxol: it may increase the risk of methemoglobinemia agents
ambroxol: it may increase the risk of methemoglobinemia agents
ambroxol: it may increase the risk of methemoglobinemia agents
ambroxol: it may increase the risk of methemoglobinemia agents
The severity of methemoglobinemia can be increased when ambroxol is taken with aminoglutethimide
may enhance the serum concentration of each other when it is combined
may enhance the serum concentration of each other when it is combined
may enhance the serum concentration of each other when it is combined
may enhance the serum concentration of each other when it is combined
may enhance the serum concentration of each other when it is combined
The potential for methemoglobinemia to occur or its seriousness may be enhanced when mepartricin is used together with ambroxol
When ambroxol is used together with fluconazole, this leads to reduction in the ambroxol metabolism
When ambroxol is used together with capsaicin, this leads to enhanced risk or seriousness of methemoglobinemia
When cyclacillin is used together with ambroxol, this leads to increased risk or seriousness of methemoglobinemia
When temocillin is used together with ambroxol, this leads to increased risk or seriousness of methemoglobinemia
When artemotil is used together with ambroxol, this leads to enhanced risk or seriousness of methemoglobinemia
when aclarubicin is combined with ambroxol, there is an increased risk of methemoglobinemia
combining beloranib with ambroxol may raise the risk or extent of methemoglobinemia
combining roquinimex with ambroxol may raise the chances of methemoglobinemia
the risk or extent of methemoglobinemia can be raised when volociximab is combined with ambroxol
when protionamide is combined with ambroxol, the chances of methemoglobinemia may be increased
When clomocycline is used together with ambroxol, this leads to enhanced risk or seriousness of methemoglobinemia
the risk or extent of methemoglobinemia can be raised when sulfanilamide is combined with ambroxol
ambroxol: it may increase the risk of methemoglobinemia with ceforanide
the risk of methemoglobinemia may be increased when benzylpenicillolyl polylysine is taken with ambroxol
the potential for methemoglobinemia can be heightened when brexucabtagene autoleucel is used in conjunction with ambroxol
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia can be increased
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia can be increased
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia may be increased
altretamine: it may increase the risk of methemoglobinemia with ambroxol
artesunate: it may increase the risk of methemoglobinemia with ambroxol
asciminib: it may increase the risk of methemoglobinemia with ambroxol
bacitracin: it may increase the risk of methemoglobinemia with ambroxol
belzutifan: it may increase the risk of methemoglobinemia with ambroxol
cabergoline: it may increase the risk of methemoglobinemia with ambroxol
cabozantinib: it may increase the risk of methemoglobinemia with ambroxol
cannabidiol: It may increase the risk or severity of methemoglobinemia with ambroxol
dapsone: it may increase the risk of methemoglobinemia with ambroxol
daratumumab: it may increase the risk of methemoglobinemia with ambroxol
darunavir: it may decrease the metabolism of ambroxol
enfortumab vedotin: it may increase the of methemoglobinemia with ambroxol
enoxacin: it may increase the risk of methemoglobinemia with ambroxol
entrectinib: it may increase the risk of methemoglobinemia with ambroxol
epcoritamab: it may increase the serum concentration of ambroxol
Actions and Spectrum
ambroxol is a mucolytic agent that works by thinning and loosening mucus in the airways, making it easier to cough up and clear from the respiratory tract. They increase the production of a thinner, less viscous mucus and by stimulating the activity of cilia.
Frequency not defined
Rash
Pruritus
Urticaria
Anaphylactic shock
Angioedema
Dyspepsia
Nausea
Vomiting
Abdominal pain
Heartburn
Bloated feeling
Dry mouth or throat
Dysgeusia
Oral and pharyngeal hypoaesthesia
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
ambroxol is a mucolytic agent. It works by increasing the production of surfactant in the respiratory tract, which helps to reduce the surface tension of mucus, making it less viscous and easier to clear.
Pharmacodynamics
ambroxol promotes the activity of cilia, which are tiny, hair-like structures lining the respiratory tract. This increased ciliary movement helps transport mucus out of the airways, facilitating its clearance.
Pharmacokinetics
Absorption
ambroxol is well-absorbed from the gastrointestinal tract.
Distribution
ambroxol is distributed throughout the body.
Metabolism
ambroxol is metabolized primarily in the liver, mainly through conjugation with glucuronic acid.
Elimination and excretion
ambroxol is primarily excreted in the urine.
Administration
ambroxol is taken orally and it is available in tablet, capsule, and syrup forms.
It is also inhale by using nebulizer in form of solution.
Patient information leaflet
Generic Name: ambroxol
Why do we use ambroxol?
ambroxol is used to liquefy and thin mucus in the respiratory tract.
ambroxol is used in conditions characterized by excessive and thick mucus production, such as acute and chronic bronchitis, asthma with excessive mucus production and cystic fibrosis.
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