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Brand Name :
Spherulin
Synonyms :
coccidioidin skin test
Class :
In vivo diagnostic biologicals
Not determined Â
Refer to adult dosingÂ
may decrease the diagnostic effect when combined with coccidioides immitis skin test
may decrease the diagnostic effect when combined with coccidioides immitis skin test
may decrease the diagnostic effect when combined with coccidioides immitis skin test
may decrease the diagnostic effect when combined with coccidioides immitis test
may decrease the diagnostic effect when combined with coccidioides immitis test
may decrease the diagnostic effect when combined with coccidioides immitis test
may decrease the diagnostic effect when combined with coccidioides immitis test
may decrease the diagnostic effect when combined with coccidioides immitis test
may decrease the diagnostic effect when combined with coccidioides skin test
may decrease the diagnostic effect when combined with coccidioides skin test
may decrease the diagnostic effect when combined with coccidioides skin test
may decrease the diagnostic effect when combined with coccidioides skin test
may decrease the diagnostic effect when combined with coccidioides skin test
may decrease the diagnostic effect
may decrease the diagnostic effect of immunosuppressants
may decrease the diagnostic effect of immunosuppressants
may decrease the diagnostic effect of immunosuppressants
may decrease the diagnostic effect of immunosuppressants
may decrease the diagnostic effect of immunosuppressants
may decrease the diagnostic effect of Immunosuppressive agents
may decrease the diagnostic effect of immunosuppressants
may decrease the diagnostic effect of Immunosuppressants
antithymocyte globulin equineÂ
may decrease the diagnostic effect of immunosuppressants
may decrease the diagnostic effect of Immunosuppressants
abiraterone acetate and niraparibÂ
may decrease the diagnostic effect of Immunosuppressants
triamcinolone acetonide/nystatin
It may enhance the risk of adverse effects when combined with diagnostic agents
It may enhance the risk of adverse effects when combined with diagnostic agents
methenamine/sodium salicylate/benzoic acid
It may enhance the risk of adverse effects when combined with diagnostic agents
It may enhance the risk of adverse effects when combined with diagnostic agents
It may enhance the risk of adverse effects when combined with diagnostic agents
when both drugs are combined, there may be a reduced response to the skin test   
when both drugs are combined, there may be a reduced response to the skin test 
it may diminish the excretion rate when combined with corifollitropin alfa resulting in an enhanced serum level
spironolactone and hydrochlorothiazide
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
It may enhance the risk of nephrotoxicity when combined with Dopamine agonists
Actions and SpectrumÂ
Coccidioidin skin test, also known as the coccidioidomycosis skin test is a diagnostic test used to assess exposure to the fungus coccidioides.Â
The coccidioidin skin test involves the injection of an antigen called coccidioidin or spherulin into the skin.
Frequency not defined Â
None
Black Box WarningÂ
None
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
The injection of coccidioidin into the skin initiates an immune response. In individuals with exposure to coccidioides, their immune system recognizes the foreign antigen.Â
PharmacodynamicsÂ
Coccidioidin skin test primarily assesses cell-mediated immunity. It is a delayed-type hypersensitivity (DTH) reaction. Â
PharmacokineticsÂ
Limited information available on ADME.Â
AdministrationÂ
Coccidioidin skin test is administered through intradermal injection.Â
Patient information leafletÂ
Generic Name: coccidioidin skin testÂ
Why do we use coccidioidin skin test?Â
The use of the coccidioidin skin test is to detect previous exposure to Coccidioides.Â
It is the fungus responsible for causing coccidioidomycosis.Â