Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Multaq
Synonyms :
dronedarone
Class :
Antiarrhythmic agent, Class III
Brand Name :
Multaq
Synonyms :
dronedarone
Class :
Antiarrhythmic agent, Class III
Dosage Forms & StrengthsÂ
Tablet, Oral:Â
400 mgÂ
400
mg
Tablet
oral
twice a day
Note: Not recommended for permanently atrial fibrillation and symptomatic heart failure patients.
No safe and efficacious dosing is availableÂ
Refer to adult dosingÂ
It may enhance the effect when combined with lonafarnib by affecting CYP3A4 metabolism
may have an increased bradycardic effect when combined with beta-blockers
may have an increased bradycardic effect when combined with beta-blockers
may have an increased bradycardic effect when combined with beta-blockers
may have an increased bradycardic effect when combined with beta-blockers
may have an increased bradycardic effect when combined with beta-blockers
dronedarone: they may increase the bradycardic effect of Beta-Blockers
dronedarone: they may increase the QTc-prolonging effect of QTc-prolonging miscellaneous agents
dronedarone: they may increase the QTc-prolonging effect of QTc-prolonging miscellaneous agents
dronedarone: they may increase the QTc-prolonging effect of QTc-prolonging miscellaneous agents
dronedarone: they may increase the QTc-prolonging effect of QTc-prolonging miscellaneous agents
dronedarone: they may increase the QTc-prolonging effect of QTc-prolonging miscellaneous agents
dronedarone and gilteritinib, when used in combination, increase the QTc interval
when both drugs are combined, there may be an increase in the QTC interval
may increase the bradycardic effect of beta blockers
may increase the bradycardic effect of beta blockers
moexipril/hydrochlorothiazideÂ
may increase the bradycardic effect of beta blockers
It may enhance QTc interval when combined with pentamidine
may enhance the serum concentration when combined
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
It may diminish the effect when combined with phenobarbital by affecting the intestinal/hepatic enzyme CYP3A4
It may enhance QTc interval when combined with perphenazine
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
It may enhance the effect when combined with pemigatinib by affecting CYP3A4 metabolism
It may diminish the effect when combined with griseofulvin by CYP3A4 metabolism
It may enhance the effect when combined with miconazole vaginal by affecting CYP3A4 metabolism
nafcillin will decrease the effect of action of dronedarone by affecting enzyme CYP3A4 metabolism.
QTc interval is increased both by lenvatinib and dronedarone
may increase the QT-prolonging effect
CYP3A strong enhancers of the small intestine may reduce the bioavailability of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
Norepinephrine Reuptake Inhibitors increase arrhythmia, causing the effect of dronedarone
may increase the arrhythmogenic effect
It may enhance the effect when combined with irinotecan liposomal by affecting CYP3A4 metabolism
It may enhance the effect when combined with cannabidiol by affecting CYP3A4 metabolism
It may enhance QTc interval when combined with lithium
It may enhance the levels when combined with tamsulosin by affecting CYP3A4 metabolism
When dronedarone is used together with givinostat, this leads to enhanced risk or severity of Qtc prolongation
When dronedarone is used together with oleandomycin, this leads to enhanced concentration serum of dronedarone
When dronedarone is used together with ridaforolimus, this leads to enhanced concentration serum of dronedarone
dronedarone: it may enhance serum concentrations of simvastatin
increase the therapeutic effect of daunorubicin by P-glycoprotein efflux transporter
the effect of dronedarone is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
increases serum level of cabazitaxel by affecting the enzyme CYP3A4
may enhance serum levels of docetaxel by affecting the MDR1/PG-P efflux transporter
may enhance serum levels of erdafitinib by affecting the MDR1/PG-P efflux transporter
increase the therapeutic effect of idarubicin by P-glycoprotein efflux transporter
QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics
QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics
QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics
QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics
QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics
may have a decrease in excretion when combined with dronedarone
Frequency defined:Â Â Â
Significant:Â
New onset or worsening heart failure symptomsÂ
HF with a reduced ejection fractionÂ
Lower wall motion indexÂ
Increased liver enzymesÂ
Acute hepatic failureÂ
Prolonged QT interval on ECGÂ
Interstitial pulmonary diseaseÂ
Pneumonitis Â
>10%Â
Increased serum creatinine Â
1% to 10%Â
BradycardiaÂ
Abdominal painÂ
DiarrheaÂ
DyspepsiaÂ
NauseaÂ
VomitingÂ
AstheniaÂ
Skin photosensitivity  Â
PostmarketingÂ
Atrial flutterÂ
Heart failureÂ
AnaphylaxisÂ
AngioedemaÂ
Pregnancy consideration: Few adverse effects were reported in animal reproductive studies. Contradicted for pregnant women.Â
Lactation: excretion of dronedarone in breast milk is not known. Â
Pregnancy category:Â
Patient information leafletÂ
Generic Name: DronedaroneÂ
Pronounced: dronedarone Â
Why do we use dronedarone?Â
Dronedarone is used for the treatment of atrial fibrillation.Â
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