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Brand Name :
Ketalar
Synonyms :
Class :
General Anesthetics, Systemic
Dosage forms & Strengths:
Adult:
Solution for injection:
10 mg/ml
50 mg/ml
100 mg/ml
Indicated for induction of anesthesia
:
1-4.5 mg/kg intravenously once
After that, 50% of the intravenous dose as and when required
Indicated for induction of anesthesia
:
1.5-2 mg/kg intravenously once
After that, 50% of the intravenous dose as and when required
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may enhance the CNS depressant effect
It may increase the arrhythmogenic effect when combined with epinephrine (Systemic)
CYP3A strong enhancers of the small intestine may reduce the bioavailability of ketamine
CNS depressants increase the effect of orphenadrine
it increases the effect of CNS depressants
CNS depressants increase the CNS depressing effect of thalidomide
CNS depressants increase the effect of flunarizine
it increases the effect of CNS depressants
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
may increase the CNS depressant effect of cannabinoid-containing products
may increase the CNS depressant effect of cannabinoid-containing products
may increase the CNS depressant effect of opioid agonists
may increase the CNS depressant effect of opioid agonists
may increase the CNS depressant effect of opioid agonists
It may enhance the effect when combined with cannabidiol by diminishing metabolism
inhalational anesthetics increase the effect of hypotension of calcium channel blockers
inhalational anesthetics increase the effect of hypotension of calcium channel blockers
inhalational anesthetics increase the effect of hypotension of calcium channel blockers
inhalational anesthetics increase the effect of hypotension of calcium channel blockers
inhalational anesthetics increase the effect of hypotension of calcium channel blockers
The potential for increased CNS depression risk or seriousness occurs when ketamine is used together with pinazepam
The potential for increased CNS depression risk or seriousness occurs when ketamine is used together with pipecuronium
The potential for CNS depression may enhanced when ketamine is used together with fencamfamin
When ketamine is used together with niaprazine, the risk or seriousness of CNS depression is enhanced
When ketamine is used together with levosulpiride, the risk or seriousness of CNS depression is enhanced
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with general anesthesia
It may enhance the risk of adverse effects when combined with inorganic compounds
It may enhance the risk of adverse effects when combined with inorganic compounds
It may enhance the risk of adverse effects when combined with inorganic compounds
ketamine: it may increase the risk of adverse effects with CYP3A4 inhibitors
ketamine: it may increase the risk of adverse effects with CYP3A4 inhibitors
ketamine: it may increase the risk of adverse effects with CYP3A4 inhibitors
ketamine: it may increase the risk of adverse effects with CYP3A4 inhibitors
ketamine: it may increase the risk of adverse effects with CYP3A4 inhibitors
when both drugs are combined, there may be a decreased level of serum concentration of ketamine
it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics
it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics
it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics
it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics
it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
CNS depressants increase the toxicity of CNS depressants
may increase the CNS depressant effect
may increase the hypotensive effect of calcium channel blockers
may increase the arrhythmogenic effect of Inhalational Anaesthetics
When ketamine is used together in combination with profenamine, this leads to reduction in therapeutic effectiveness of profenamine
CNS depressants increases the toxicity of bupivacaine
>10%:
Emergency reactions
HTN
Tonic-clonic movements
Increased cardiac output
Vivid dreams
Visual hallucinations
Increased cardiac output
Increased ICP
Tachycardia
1-10%:
Increased IOP
Nystagmus
Injection-site pain
Bradycardia
Diplopia
Hypotension
<1%:
Fasciculations
Hypersalivation
Increased IOP
Anaphylaxis
Depressed cough reflex
Cardiac arrhythmia
Hypertonia
Laryngospasm
Ketamine is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients.
Pregnancy consideration:
No sufficient data is available regarding the use of the drug during pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of the drug in breast milk.
Pregnancy category:
Patient information leaflet
Generic Name: ketamine
Pronounced: keeh-tah-mine
Why do we use ketamine?
Ketamine belongs to the category of general anesthetics. It is used to induce anesthesia.