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Brand Name :
ProQuad
Synonyms :
measles, mumps, rubella, and varicella vaccine, live (Rx)
Class :
Vaccines
Brand Name :
ProQuad
Synonyms :
measles, mumps, rubella, and varicella vaccine, live (Rx)
Class :
Vaccines
Dosage Forms & Strengths
lyophilized powder for reconstitution, injection
≥1000 TCID50/≥13000 TCID50/≥1000 TCID50/≥1999 PFU
Indicated for Measles, Rubella, Mumps,& Varicella Vaccination:
Two-step dose vaccination:
1st dose- 0.5ml subcutaneous, at age 12-15 months
2nd dose- 0.5ml subcutaneous, at age 4-6 years
Indicated for Measles, Rubella, Mumps,& Varicella Vaccination:
Two-step dose vaccination:
1st dose- 0.5ml subcutaneous, at age 12-15 months
2nd dose- 0.5ml subcutaneous, at age 4-6 years
Not indicated
measles, mumps, rubella, and varicella vaccine, live (Rx)
may diminish the therapeutic effect of other vaccines (live)
measles mumps and rubella vaccine, live
may diminish the therapeutic effect of other vaccines (live)
may diminish the therapeutic effect of other vaccines (live)
smallpox (vaccinia) vaccine, live
may diminish the therapeutic effect of other vaccines (live)
may diminish the therapeutic effect of other vaccines (live)
may decrease the therapeutic effect of immunosuppressants
may decrease the therapeutic effect of immunosuppressants
may decrease the therapeutic effect of immunosuppressants
may diminish the immunosuppressive effect of each other when combined
may diminish the immunosuppressive effect of each other when combined
may diminish the immunosuppressive effect of each other when combined
may diminish the immunosuppressive effect of each other when combined
may diminish the immunosuppressive effect of each other when combined
may enhance the adverse/toxic effect of varicella virus-containing vaccines
may enhance the adverse/toxic effect of varicella virus-containing vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may enhance the risk of adverse/toxic effect of rubella- or varicella-containing live vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
measles, mumps, rubella, and varicella vaccine, live (Rx)
may diminish the therapeutic effect of other vaccines (live)
measles mumps and rubella vaccine, live
may diminish the therapeutic effect of other vaccines (live)
may diminish the therapeutic effect of other vaccines (live)
smallpox (vaccinia) vaccine, live
may diminish the therapeutic effect of other vaccines (live)
may diminish the therapeutic effect of other vaccines (live)
may decrease the therapeutic effect of corticosteroids
may decrease the therapeutic effect of immunosuppressants
may decrease the therapeutic effect of immunosuppressants
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may diminish the therapeutic effect of vaccines
may increase the toxic effect of immunosuppressants
may increase the adverse effect of corticosteroids
may decrease the therapeutic effect of immunosuppressants
may decrease the therapeutic effect of immunosuppressants
may decrease the therapeutic effect of immunosuppressants
it may increase the risk of adverse effects of vaccines
it may increase the risk of adverse effects of vaccines
it may increase the risk of adverse effects of vaccines
it may increase the risk of adverse effects of vaccines
it may increase the risk of adverse effects of vaccines
it may increase the risk of adverse effects of vaccines
it may increase the risk of adverse effects of vaccines
it may increase the risk of adverse effects of vaccines
it may reduce the therapeutic efficacy of vaccines
may reduce the therapeutic effect of vaccines
may reduce the therapeutic effect of vaccines
may reduce the therapeutic effect of vaccines
may reduce the therapeutic effect of vaccines
may reduce the therapeutic effect of vaccines
may reduce the therapeutic effect of vaccines
may diminish the therapeutic effect
amoxicillin and clavulanate potassium
may diminish the therapeutic effect
bismuth subcitrate, metronidazole and tetracycline
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
lansoprazole, amoxicillin, and clarithromycin
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
may diminish the therapeutic effect
It may decrease the therapeutic effect when combined with Rho(D) Immune Globulin
immune globulins: it may decrease the therapeutic effect of vaccines (Live)
immune globulins: it may decrease the therapeutic effect of vaccines (Live)
immune globulins: it may decrease the therapeutic effect of vaccines (Live)
immune globulins: it may decrease the therapeutic effect of vaccines (Live)
immune globulins: it may decrease the therapeutic effect of vaccines (Live)
may reduce the therapeutic efficacy of the drug
acetaminophen: they may decrease the therapeutic effect of vaccines
cladribine: they may decrease the therapeutic effect of vaccines
corticosteroids: they may decrease the therapeutic effect of vaccines
corticosteroids: they may decrease the therapeutic effect of vaccines
corticosteroids: they may decrease the therapeutic effect of vaccines
corticosteroids: they may decrease the therapeutic effect of vaccines
corticosteroids: they may decrease the therapeutic effect of vaccines
methotrexate: they may decrease the therapeutic effect of vaccines
teplizumab: they may decrease the therapeutic effect of vaccines
fingolimod: they may decrease the therapeutic effect of vaccines
propacetamol: they may decrease the therapeutic effect of vaccines
siponimod: they may decrease the therapeutic effect of vaccines
may enhance the adverse/toxic effect of rubella, and varicella vaccine, live
may enhance the adverse/toxic effect of rubella, and varicella vaccine, live
may enhance the adverse/toxic effect of rubella, and varicella vaccine, live
may enhance the adverse/toxic effect of rubella, and varicella vaccine, live
may enhance the adverse/toxic effect of rubella, and varicella vaccine, live
immunosuppressants increase the toxicity of live vaccines
immunosuppressants increase the toxicity of live vaccines
immunosuppressants increase the toxicity of live vaccines
immunosuppressants increase the toxicity of live vaccines
immunosuppressants increase the toxicity of live vaccines
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may enhance the adverse/toxic effect of rubella, and varicella vaccine, live
may increase the toxic effect of salicylates
may increase the adverse effect of Immunosuppressants
may have an increasingly adverse effect when combined with poliovirus vaccine (live/trivalent/oral)
may have an increasingly adverse effect when combined with poliovirus vaccine (live/trivalent/oral)
may have an increasingly adverse effect when combined with poliovirus vaccine (live/trivalent/oral)
dupilumab: they may increase the toxic effect of vaccines
famciclovir: they may increase the toxic effect of vaccines
ozanimod: they may increase the toxic effect of vaccines
tezepelumab: they may increase the toxic effect of vaccines
immune globulins decrease the efficacy of live vaccines
immune globulins decrease the efficacy of live vaccines
immune globulins decrease the efficacy of live vaccines
immune globulins decrease the efficacy of live vaccines
immune globulins decrease the efficacy of live vaccines
may enhance the adverse/toxic effect of vaccines
may enhance the adverse/toxic effect of vaccines
may diminish the immunosuppressive effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the immunosuppressive effect of each other when combined
may diminish the immunosuppressive effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may diminish the pharmacodynamic antagonistic effect of each other when combined
may decrease the therapeutic effect of immunosuppressive Agents
may decrease the therapeutic effect of immunosuppressive Agents
may decrease the therapeutic effect of immunosuppressive Agents
may decrease the therapeutic effect of immunosuppressive Agents
may decrease the therapeutic effect of immunosuppressive Agents
dimethyl fumarate: they may increase the toxic effect of vaccines
leniolisib: they may increase the toxic effect of vaccines
immunosuppressants decrease the efficacy of vaccines
immunosuppressants decrease the efficacy of vaccines
immunosuppressants decrease the efficacy of vaccines
immunosuppressants decrease the efficacy of vaccines
immunosuppressants decrease the efficacy of vaccines
it decreases the efficacy of live vaccines
they decrease the efficacy of live vaccines
they decrease the efficacy of live vaccines
they decrease the efficacy of live vaccines
they decrease the efficacy of live vaccines
they decrease the efficacy of live vaccines
Frequency defined:
>10%
Injection site erythema
Fever>102°F
Injection site pain/tenderness/soreness
1-10%
Irritability
Rash
Injection site swelling
Post-marketing reports
Epididymitis
Extravasation
Erythema multiforme
Hematochezia
Respiratory disorders-pneumonia, sore throat, wheezing, rhinitis, epistaxis
Blood and lymphatic system disorders-thrombocytopenia, aplastic anemia
Psychiatric disorders-nervousness, agitation, apathy
Ear and labyrinth disorders-nerve deafness
Mouth ulcer
Abdominal pain
Pregnancy consideration: Pregnancy is contraindicated; prevent pregnancy for three months after vaccination
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient information leaflet
Generic Name: measles, mumps, rubella, and varicella vaccine, live (Rx)
Pronounced: [MEE-zels, MUMPS, roo-BEL-a, var-i-SEL-a]
Why do we use the measles, mumps, rubella, and varicella vaccine live?
It is an active immunizing substance administered to provide defense against infections brought on by the measles (rubella), mumps, rubella (German measles), and varicella (chicken pox) viruses
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