The Navigation Model of Therapy: Why Awareness Changes Everything
November 16, 2025
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Brand Name :
Inversine, Vecamyl
Synonyms :
mecamylamine
Class :
Antihypertensives
Brand Name :
Inversine, Vecamyl
Synonyms :
mecamylamine
Class :
Antihypertensives
Dosage Forms & Strengths Â
Tablet Â
2.5mg Â
2.5
mg
Orally 
twice a day
; increase to 2.5 mg for at least 2 days
may increase the adverse effect of thiazide diuretics
may increase the adverse effect of thiazide diuretics
may increase the adverse effect of thiazide diuretics
may increase the adverse effect of thiazide diuretics
methyldopa/hydrochlorothiazideÂ
may enhance the toxic effect of thiazide and thiazide like diuretics
may have an increased neuromuscular-blocking effect when combined with mecamylamine
mecamylamine: they may increase the toxic effect of sulfonamides
mecamylamine: they may increase the toxic effect of sulfonamides
aminoglycosides increase the effect of neuromuscular blockage of mecamylamine
neomycin/polymyxin B/bacitracin topical
aminoglycosides increase the effect of neuromuscular blockage of mecamylamine
aminoglycosides increase the effect of neuromuscular blockage of mecamylamine
aminoglycosides increase the effect of neuromuscular blockage of mecamylamine
aminoglycosides increase the effect of neuromuscular blockage of mecamylamine
sulfonamides increase the toxic or adverse effects of mecamylamine
tetracyclines increase the neuromuscular blocking property of mecamylamine
may increase the neuromuscular-blocking effect
neomycin/polymyxin B/gramicidin ophthalmicÂ
may increase the nephrotoxic effect of Polymyxin B
colistimethate increases the neuromuscular blocking effect of mecamylamine
spironolactone and hydrochlorothiazide
may increase the sensitivity to pressor effects
may increase the sensitivity to pressor effects
may increase the sensitivity to pressor effects
may increase the sensitivity to pressor effects
may increase the sensitivity to pressor effects
It may enhance the serum concentration when combined with alkalinizing agents
It may enhance the serum concentration when combined with alkalinizing agents
It may enhance the serum concentration when combined with alkalinizing agents
It may enhance the serum concentration when combined with alkalinizing agents
It may enhance the serum concentration when combined with alkalinizing agents
mecamylamine: they may enhance the serum concentration of alkalinizing agents
mecamylamine: they may enhance the serum concentration of alkalinizing agents
mecamylamine: they may enhance the serum concentration of alkalinizing agents
mecamylamine: they may enhance the serum concentration of alkalinizing agents
mecamylamine: they may enhance the serum concentration of alkalinizing agents
mecamylamine: they may diminish the serum concentration of urinary acidifying agents
mecamylamine: they may diminish the serum concentration of urinary acidifying agents
mecamylamine: they may diminish the serum concentration of urinary acidifying agents
When mecamylamine is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
It may enhance the risk of adverse effects when combined with monoamine oxidase
It may enhance the risk of adverse effects when combined with monoamine oxidase
It may enhance the risk of adverse effects when combined with monoamine oxidase
It may enhance the risk of adverse effects when combined with monoamine oxidase
Adverse drug reactions Â
Frequency Not Defined Â
Nausea/Vomiting Â
Lightheadedness Â
Orthostatic hypotension Â
Fatigue Â
Dry mouth Â
Xerostomia Â
Sedation Â
Constipation Â
Â
Â
Pregnancy warnings:   
Pregnancy Category: CÂ
Lactation: Â
The drug excretion in breast milk is known. Â
Pregnancy Categories:       Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.  Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category Â
 Â
Patient Information Leaflet   Â
Generic Name: mecamylamineÂ
Why do we use mecamylamine? Â
mecamylamine is an Antihypertensives used to treat Hypertension.Â
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