Performance Comparison of Microfluidic and Immunomagnetic Platforms for Pancreatic CTC Enrichment
November 15, 2025
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Brand Name :
N/A
Synonyms :
Matromycin, Landomycin,Amimycin
Class :
Macrolide antibiotics
Brand Name :
N/A
Synonyms :
Matromycin, Landomycin,Amimycin
Class :
Macrolide antibiotics
Dosage forms and strengths Â
Oral tabletÂ
500 mgÂ
Upper Respiratory Tract ConditionsÂ
Indicated for upper respiratory tract infections
In vivo, data suggests taking 500 mg orally four times a day
The treatment duration is five days
Indicated for Non-specific urethritis
In vivo, data suggests taking 500 mg orally four times a da
The treatment duration is five days
Indicated for non-specific urethritis
In vivo, data suggests taking 500 mg orally four times a day
The treatment duration is five days
Upper Respiratory Tract ConditionsÂ
Indicated for upper respiratory tract infections
In vivo, data suggests taking 500 mg orally four times a day
The treatment duration is five days
Not indicatedÂ
Refer adult dosingÂ
When abemaciclib is used together with oleandomycin, this leads to enhanced concentration serum of abemaciclib
When acalabrutinib is used together with oleandomycin, this leads to enhanced concentration serum of acalabrutinib
When acenocoumarol is used together with oleandomycin, this leads to enhanced concentration serum of acenocoumarol
When alectinib is used together with oleandomycin, this leads to enhanced concentration serum of alectinib
When alfentanil is used together with oleandomycin, this leads to enhanced concentration serum of alfentanil
When alpelisib is used together with oleandomycin, this leads to enhanced concentration serum of alpelisib
When alprazolam is used together with oleandomycin, this leads to enhanced concentration serum of alprazolam
When aminophylline is used together with oleandomycin, this leads to enhanced concentration serum of aminophylline
When amiodarone is used together with oleandomycin, this leads to enhanced concentration serum of amiodarone
When astemizole is used together with oleandomycin, this leads to enhanced concentration serum of astemizole
When axitinib is used together with oleandomycin, this leads to enhanced concentration serum of axitinib
When bicalutamide is used together with oleandomycin, this leads to enhanced concentration serum of bicalutamide
When bortezomib is used together with oleandomycin, this leads to enhanced concentration serum of bortezomib
When bosutinib is used together with oleandomycin, this leads to enhanced concentration serum of bosutinib
When bromocriptine is used together with oleandomycin, this leads to enhanced concentration serum of bromocriptine
When budesonide is used together with oleandomycin, this leads to enhanced concentration serum of budesonide
When busulfan is used together with oleandomycin, this leads to enhanced concentration serum of busulfan
When cabazitaxel is used together with oleandomycin, this leads to enhanced concentration serum of cabazitaxel
When cabergoline is used together with oleandomycin, this leads to enhanced concentration serum of cabergoline
When ceritinib is used together with oleandomycin, this leads to enhanced concentration serum of ceritinib
When cisapride is used together with oleandomycin, this leads to enhanced concentration serum of cisapride
When clomipramine is used together with oleandomycin, this leads to enhanced concentration serum of clomipramine
When clonidine is used together with oleandomycin, this leads to enhanced concentration serum of clonidine
When clozapine is used together with oleandomycin, this leads to enhanced concentration serum of clozapine
When cobimetinib is used together with oleandomycin, this leads to enhanced concentration serum of cobimetinib
When corticotropin is used together with oleandomycin, this leads to enhanced concentration serum of corticotropin
When crizotinib is used together with oleandomycin, this leads to enhanced concentration serum of crizotinib
When cyclophosphamide is used together with oleandomycin, this leads to enhanced concentration serum of abemaciclib
When dabrafenib is used together with oleandomycin, this leads to enhanced concentration serum of dabrafenib
When dacomitinib is used together with oleandomycin, this leads to enhanced concentration serum of dacomitinib
When dasatinib is used together with oleandomycin, this leads to enhanced concentration serum of dasatinib
When deslanoside is used together with oleandomycin, this leads to enhanced concentration serum of deslanoside
When dexamethasone is used together with oleandomycin, this leads to enhanced concentration serum of dexamethasone
When dicoumarol is used together with oleandomycin, this leads to enhanced concentration serum of dicoumarol
When digitoxin is used together with oleandomycin, this leads to enhanced concentration serum of digitoxin
When digoxin is used together with oleandomycin, this leads to enhanced concentration serum of digoxin
When dihydroergocornine is used together with oleandomycin, this leads to enhanced concentration serum of dihydroergocornine
When dihydroergocristine is used together with oleandomycin, this leads to enhanced concentration serum of dihydroergocristine
When dihydroergotamine is used together with oleandomycin, this leads to enhanced concentration serum of dihydroergotamine
When docetaxel is used together with oleandomycin, this leads to enhanced concentration serum of docetaxel
When dofetilide is used together with oleandomycin, this leads to enhanced concentration serum of dofetilide
When doxorubicin is used together with oleandomycin, this leads to enhanced concentration serum of doxorubicin
When dronabinol is used together with oleandomycin, this leads to enhanced concentration serum of dronabinol
When dronedarone is used together with oleandomycin, this leads to enhanced concentration serum of dronedarone
When enasidenib is used together with oleandomycin, this leads to enhanced concentration serum of enasidenib
When enzalutamide is used together with oleandomycin, this leads to enhanced concentration serum of enzalutamide
When ergometrine is used together with oleandomycin, this leads to enhanced concentration serum of ergometrine
When ergotamine is used together with oleandomycin, this leads to enhanced concentration serum of ergotamine
When estazolam is used together with oleandomycin, this leads to enhanced concentration serum of estazolam
Actions and Spectrum:Â
Action:Â
Oleandomycin is a macrolide antibiotic that acts by inhibiting bacterial protein synthesis. It attaches to susceptible bacteria’s 50S ribosomal subunit, preventing the elongation of polypeptide chains during protein synthesis. This interference with protein production disrupts bacterial growth and leads to bacterial cell death.Â
Spectrum:Â
Oleandomycin demonstrates broad-spectrum antibacterial activity against various gram-positive bacteria, including Streptococcus pneumoniae, Streptococcus pyogenes, & certain other gram-positive organisms. Â
Â
Frequency not defined Â
HeadacheÂ
Fatigue Â
Dizziness Â
Abdominal pain or crampingÂ
DiarrheaÂ
VomitingÂ
NauseaÂ
Black Box Warning:Â Â
None
Contraindication/Caution:Â Â
Allergic reaction: Individuals with a known hypersensitivity or allergy to oleandomycin or any other macrolide antibiotics should avoid its use.Â
Liver disease: Patients with severe liver impairment or a history of liver disease should use oleandomycin with caution or avoid it altogether. Â
Pregnancy and breastfeeding: The safety of oleandomycin during pregnancy and breastfeeding hasn’t been extensively studied. It is generally advised against using it while pregnant unless the advantages outweigh the possible risks. Similarly, caution is advised when breastfeeding.Â
Pregnancy warnings:    Â
Pregnancy category: N/AÂ
Lactation: Excreted into human milk is unknownÂ
Pregnancy Categories:        Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.Â
Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
Pharmacology: Â
Oleandomycin is a class of the macrolide antibiotics.Â
Pharmacodynamics:Â Â
Oleandomycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible organisms. Through attachment to the 50S ribosomal subunit’s 23S RNA, it prevents the translocation of peptidyl tRNA and inhibits the synthesis of bacterial proteins. This interference disrupts the bacterial growth cycle, leading to eventual cell death. Â
Pharmacokinetics:Â
AbsorptionÂ
Oleandomycin is absorbed well in the gastrointestinal tract after oral administration.Â
DistributionÂ
It distributes widely throughout the body, including into tissues and fluids. The distribution volume is 0.77 L/kg.Â
MetabolismÂ
It undergoes hepatic metabolism.Â
Excretion and EliminationÂ
Elimination mainly occurs through bile and feces.Â
The elimination half-life is 1.05 hours.Â
Â
Administration: Â
The appropriate oleandomycin dosage can vary based on weight, age, and general health status of the patient.Â
Always follow your healthcare provider’s instructions regarding the use of oleandomycin.Â
Patient information leafletÂ
Generic Name: oleandomycinÂ
Why do we use oleandomycin? Â
Oleandomycin is effective against infections of the respiratory tract caused by susceptible bacteria. It can be prescribed for conditions like bronchitis, pneumonia, and sinusitis. It is used to treat skin infections such as cellulitis, impetigo, and folliculitis caused by susceptible bacteria.Â
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