Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Sytron
Synonyms :
sodium feredetate
Class :
Iron supplements
Brand Name :
Sytron
Synonyms :
sodium feredetate
Class :
Iron supplements
Dosage Forms & Strengths
syrup
27.5mg/5ml
5ml consisting of 27.5mg of iron is given as oral solution. It can be increased gradually to 10ml thrice a day
Safety and efficacy were not established
Refer to the adult dosing regimen
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the serum concentration of quinolones
methyldopa/hydrochlorothiazide
may diminish the serum concentration of methyldopa
may diminish the serum concentration of Antacids
ciprofloxacin inhaled (Pending FDA approval)
may diminish the serum concentration of Quinolones
may diminish the absorption when combined with alpha-lipoic acid
may diminish the absorption when combined with iron preparations
may diminish concentration of serum when combined with bictegravir
may diminish concentration of serum when combined with cefdinir
may diminish concentration of serum when combined with entacapone
may diminish concentration of serum when combined with levothyroxine
may diminish concentration of serum when combined with methyldopa
bismuth subcitrate, metronidazole and tetracycline
may diminish the absorption when combined with iron preparations
may diminish the absorption when combined with iron preparations
may diminish the absorption when combined with iron preparations
may diminish the absorption when combined with iron preparations
may diminish the absorption when combined with iron preparations
may diminish concentration of serum when combined with levodopa
polyethylene glycol and electrolytes
may diminish the absorption when combined with iron preparation
may increase the nephrotoxic effect of iron preparations
may decrease the rate of absorption
bismuth subcitrate, metronidazole and tetracycline
may decrease the rate of absorption
may decrease the rate of absorption
may decrease the rate of absorption
may decrease the rate of absorption
may decrease the rate of absorption
may decrease the rate of absorption
may decrease the rate of absorption
may decrease the rate of absorption
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may diminish the serum concentration of each other when combined
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
may increase the risk of adverse/toxic effects
sodium ferric gluconate complex
sodium ferric gluconate, when administered with drugs containing iron, can cause a reduction in absorption of iron, leading to potential effects due to iron
a decrease in the efficacy of ferric pyrophosphate can be seen when administered with sodium feredetate
Actions and spectrum
Iron is an essential nutrient in the body since it is a fundamental component of hemoglobin. This oral medication is prescribed for the treatment and prevention of anemia as per the standards set in the given region. Sodium feredetate does not contain iron salt and the amount of available iron in sodium feredetate is in the non-ionized state. Instead, the iron is ‘‘isolated’’ or ‘‘coated’’ with a sodium salt of ethylenediamine tetra-acetic acid and forms a ring-like structure known as a chelate. This distinctive configuration reduces astringency and eliminates color change in the teeth. Iron can be absorbed in any part of the digestive tract with majority of its absorption occurring in the small intestine. Iron being in its ferrous form is more efficiently absorbed. During their treatment, haemoglobin levels are expected to rise by a steady 1-2 g/L/day or about 20 g/L over 3-4 weeks.
Adverse Reaction
Frequency not defined
Discolouration of stools
diarrhoea
Hypersensitivity reactions
Nausea
Black Box Warning
There were no specific black box warnings associated with sodium feredetate.
Contraindication/Caution
Contraindication
Hypersensitivity
Hemochromatosis or Iron Overload Disorders
Thalassemia
Caution
Gastrointestinal Distress
Iron Overload Risk
Thyroid Disorders
Pregnancy/Lactation
Pregnancy consideration: Pregnancy category: Not assigned
Lactation: Excreted into human milk: unknown
Pregnancy category:
Pharmacology
It is an iron supplement which is prescribed to iron deficiency anemic patients. It includes ferrous and ferric iron to enhance the absorbability within the gastrointestinal system. It is usually taken in the form of tablet or solution orally, enhancing patient compliance and management of erythropoietic activity.
Pharmacodynamics
Iron is present in large quantity in sodium feredetate. The haemoglobin biosynthesis process could also be improved so that it replaces the depleted supplies of iron. It is used in the management and prevention of anaemia, a process which is sometimes referred to as anaemia prophylaxis.
Pharmacokinetics
Absorption
It is primarily absorbed in the small intestine and is more readily absorbed in its ferrous state
Distribution:
It contains iron in a chelated form with EDTA, which helps in distributing the iron effectively throughout the body.
Metabolism
The iron from sodium feredetate is utilized in the body primarily to produce hemoglobin
Elimination/Excretion
Excess iron that is not absorbed or utilized by the body is excreted mainly through feces. The chelating agent, EDTA, is also excreted primarily via the urine.
Administration
It is given orally
Patient information leaflet
Generic Name: sodium feredetate
Pronounced: (SOH-dee-um fer-ED-eh-tate)
Why do we use sodium feredetate?
Sodium Feredetate is used in treatment of Iron deficiency anaemia. It is used clinically as an anti-anemic drug.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
