Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Brand Name :
Enjuvia, Premarin
Synonyms :
synthetic conjugated estrogens B
Class :
Estrogen derivatives
Dosage Forms & StrengthsÂ
TabletsÂ
0.3mgÂ
0.45mgÂ
0.625mgÂ
0.9mgÂ
1.25mgÂ
Initial dose: 0.3mg orally one time a day:
0.3
mg
Tablets
Orally 
once a day
Maintenance dose: 0.45- 1.25mg orally one time a day
0.3
mg
Tablets
Orally 
once a day
0.3
mg
Tablets
Orally 
once a day
25
mg
Solution
Intramuscular (IM)
twice or thrice daily
0.3 - 0.625
mg
Tablets
Orally 
once a day
3
weeks
0.3 - 0.625
mg
Tablets
Orally 
3
weeks
1.25 - 2.5
mg
Tablets
Orally 
3 times a day
1.25 - 2.5
mg
Tablets
Orally 
3 times a day
Palliative Treatment Of Breast CarcinomaÂ
10
mg
Tablets
Orally 
3
months
Dosage Forms & StrengthsÂ
Data not availableÂ
Refer to adult dosingÂ
the activity of fezolinetant will be increased
cyproterone and ethinyl estradiolÂ
may decrease the diagnostic effect of each other when combined
the activity of antithrombin III may be decreased due to pharmacodynamic antagonism
the activity of argatroban may be decreased due to pharmacodynamic antagonism
the activity of synthetic conjugated estrogens B is increased by clarithromycin
the activity of dalteparin may be decreased due to pharmacodynamic antagonism
the activity of synthetic conjugated estrogens B is increased by erythromycin base
the activity of synthetic conjugated estrogens B is increased by erythromycin ethylsuccinate
the activity of synthetic conjugated estrogens B is increased by erythromycin lactobionate
the activity of anastrozole may be decreased due to pharmacodynamic antagonism
the activity of antithrombin alfa may be decreased due to pharmacodynamic antagonism
dehydroepiandrosterone (DHEA)Â
Estrogen derivatives may increase the harmful or toxic effects of dehydroepiandrosterone
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
the activity of synthetic conjugated estrogens B is increased by erythromycin stearate
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
It may increase the thrombogenic effect when combined with C1 inhibitors
The combination of estrogen derivatives with ajmaline could potentially amplify its harmful and toxic effects
chenodiol's therapeutic effectiveness could be reduced by the presence of estrogen derivatives
an increase in thrombogenic activity of daclizumab may be seen
the activity of estrogen pills may be reduced with agnus-castus
Actions and spectrum:Â
Synthetic conjugated estrogens B plays a pivotal role in the maintenance and development of the female reproductive system, replacing natural estrogensÂ
Frequency not definedÂ
ConfusionÂ
Memory problemsÂ
Unusual behaviourÂ
A lump in the breastÂ
JaundiceÂ
Stabbing pain in the chestÂ
Pain spreading to shoulder or jawÂ
Tender stomachÂ
Severe headacheÂ
ConstipationÂ
Increased urinationÂ
Muscle weakness  Â
Vaginal itchingÂ
Breakthrough bleedingÂ
Black Box Warning Â
Risk of endometrial cancer in women Â
In the prevention of dementia or cardiovascular disease, estrogen-alone therapy is not recommended.Â
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â Â
USFDA pregnancy category: Not assignedÂ
Lactation:Â Â
The drug is found to be excreted in human milk. Hence, synthetic conjugated estrogens B should be used with caution.Â
Pregnancy category:Â Â
Pharmacology:Â
Pharmacodynamics:Â
Pharmacokinetics:Â
AbsorptionÂ
Peak plasma time is 8hoursÂ
It is absorbed from the gastrointestinal tractÂ
DistributionÂ
80% of the drug is bound to proteinsÂ
MetabolismÂ
It undergoes metabolism in the liver to glucuronides and inactive sulfates. Various metabolites are estriol, estradiol, and estrone.Â
Elimination and excretionÂ
It is eliminated mainly in the urineÂ
Half-life:Â
Administration:Â
Administer this drug as directed by the physician.Â
Patient information leafletÂ
Generic Name: synthetic conjugated estrogens BÂ
Why do we use synthetic conjugated estrogens B?Â
Synthetic conjugated estrogen B is a mixture containing estrogen hormones. The drug is used to treat various menopausal symptoms like vaginal flushes, hot flashes and also in prevention of osteoporosis.Â