Study Finds Birth Hypoxia May Increase ADHD Likelihood
January 27, 2026
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Brand Name :
Enjuvia, Premarin
Synonyms :
synthetic conjugated estrogens B
Class :
Estrogen derivatives
Brand Name :
Enjuvia, Premarin
Synonyms :
synthetic conjugated estrogens B
Class :
Estrogen derivatives
Dosage Forms & Strengths
Tablets
0.3mg
0.45mg
0.625mg
0.9mg
1.25mg
Initial dose: 0.3mg orally one time a day:
0.3
mg
Tablets
Orally
once a day
Maintenance dose: 0.45- 1.25mg orally one time a day
0.3
mg
Tablets
Orally
once a day
0.3
mg
Tablets
Orally
once a day
25
mg
Solution
Intramuscular (IM)
twice or thrice daily
0.3 - 0.625
mg
Tablets
Orally
once a day
3
weeks
0.3 - 0.625
mg
Tablets
Orally
3
weeks
1.25 - 2.5
mg
Tablets
Orally
3 times a day
1.25 - 2.5
mg
Tablets
Orally
3 times a day
Palliative Treatment Of Breast Carcinoma
10
mg
Tablets
Orally
3
months
Dosage Forms & Strengths
Data not available
Refer to adult dosing
the activity of fezolinetant will be increased
cyproterone and ethinyl estradiol
may decrease the diagnostic effect of each other when combined
the activity of antithrombin III may be decreased due to pharmacodynamic antagonism
the activity of argatroban may be decreased due to pharmacodynamic antagonism
the activity of synthetic conjugated estrogens B is increased by clarithromycin
the activity of dalteparin may be decreased due to pharmacodynamic antagonism
the activity of synthetic conjugated estrogens B is increased by erythromycin base
the activity of synthetic conjugated estrogens B is increased by erythromycin ethylsuccinate
the activity of synthetic conjugated estrogens B is increased by erythromycin lactobionate
the activity of anastrozole may be decreased due to pharmacodynamic antagonism
the activity of antithrombin alfa may be decreased due to pharmacodynamic antagonism
Estrogen derivatives may increase the harmful or toxic effects of dehydroepiandrosterone
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
may enhance the concentration of serum when combined with corticosteroids
the activity of synthetic conjugated estrogens B is increased by erythromycin stearate
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
It may increase the thrombogenic effect when combined with C1 inhibitors
The combination of estrogen derivatives with ajmaline could potentially amplify its harmful and toxic effects
chenodiol's therapeutic effectiveness could be reduced by the presence of estrogen derivatives
an increase in thrombogenic activity of daclizumab may be seen
the activity of estrogen pills may be reduced with agnus-castus
Actions and spectrum:
Synthetic conjugated estrogens B plays a pivotal role in the maintenance and development of the female reproductive system, replacing natural estrogens
Frequency not defined
Confusion
Memory problems
Unusual behaviour
A lump in the breast
Jaundice
Stabbing pain in the chest
Pain spreading to shoulder or jaw
Tender stomach
Severe headache
Constipation
Increased urination
Muscle weakness
Vaginal itching
Breakthrough bleeding
Black Box Warning
Risk of endometrial cancer in women
In the prevention of dementia or cardiovascular disease, estrogen-alone therapy is not recommended.
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
USFDA pregnancy category: Not assigned
Lactation:
The drug is found to be excreted in human milk. Hence, synthetic conjugated estrogens B should be used with caution.
Pregnancy category:
Pharmacology:
Pharmacodynamics:
Pharmacokinetics:
Absorption
Peak plasma time is 8hours
It is absorbed from the gastrointestinal tract
Distribution
80% of the drug is bound to proteins
Metabolism
It undergoes metabolism in the liver to glucuronides and inactive sulfates. Various metabolites are estriol, estradiol, and estrone.
Elimination and excretion
It is eliminated mainly in the urine
Half-life:
Administration:
Administer this drug as directed by the physician.
Patient information leaflet
Generic Name: synthetic conjugated estrogens B
Why do we use synthetic conjugated estrogens B?
Synthetic conjugated estrogen B is a mixture containing estrogen hormones. The drug is used to treat various menopausal symptoms like vaginal flushes, hot flashes and also in prevention of osteoporosis.
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