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Brand Name :
Gaviscon Extra Strength Tablets, Gaviscon Extra Strength Liquid, Gaviscon Regular Strength Liquid
Synonyms :
aluminum hydroxide/magnesium carbonate
Class :
Antacids
Brand Name :
Gaviscon Extra Strength Tablets, Gaviscon Extra Strength Liquid, Gaviscon Regular Strength Liquid
Synonyms :
aluminum hydroxide/magnesium carbonate
Class :
Antacids
Dosage Forms & Strengths
aluminum hydroxide/magnesium carbonate
Oral Suspension
(31.7mg/119.3mg)/5mL
(84.6mg/79.1mg)/5mL
(254mg/237mg)/5mL
Chewable Tablet
160mg/105mg
Extra Strength Suspension: Administer 15 to 30 mL orally 4 times whenever necessary; Do not exceed 80 mL/day
Extra Strength Tablets: Chew 2 to 4 tablets orally every 6 hours as needed; Do not exceed 16 tablets daily.
Regular Strength Suspension: Administer 15 to 30 mL orally four times a day as needed; Do not exceed 120 mL/day
Safety and efficacy not established
Refer adult dosing
may diminish the serum concentration of Antacids
may diminish the serum concentration of Aluminum Hydroxide
may diminish the absorption of Antacids
may diminish the absorption of Antacids
may diminish the absorption of Antacids
may diminish the absorption of Antacids
may diminish the absorption of Antacids
may decrease the serum concentration of Polyvalent Cation Containing Products
may decrease the serum concentration of Polyvalent Cation Containing Products
may decrease the serum concentration of Polyvalent Cation Containing Products
may decrease the serum concentration of Polyvalent Cation Containing Products
may decrease the serum concentration of Polyvalent Cation Containing Products
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
may decrease the bioavailability of antacids
bismuth subcitrate, metronidazole and tetracycline
may decrease the serum concentration of antacids
may decrease the serum concentration of antacids
may decrease the serum concentration of antacids
may decrease the serum concentration of antacids
may decrease the serum concentration of antacids
may decrease the serum concentration of antacids
may decrease the serum concentration of antacids
may decrease the serum concentration of antacids
may enhance the serum concentration of aluminum hydroxide
may enhance the serum concentration of aluminum hydroxide
may enhance the serum concentration of aluminum hydroxide
may enhance the serum concentration of aluminum hydroxide
may enhance the serum concentration of aluminum hydroxide
may enhance serum concentration of antacids
may enhance serum concentration of antacids
may enhance serum concentration of antacids
may enhance serum concentration of antacids
Actions and Spectrum:
aluminum hydroxide acts as an antacid by neutralizing excess stomach acid. It reacts with hydrochloric acid in the stomach to form water and aluminum chloride, which helps to raise the pH of gastric contents and reduce gastric acidity. magnesium carbonate also functions as an antacid by neutralizing stomach acid. It reacts with hydrochloric acid to form water and magnesium chloride, raising the stomach’s pH.
aluminum hydroxide effectively relieves symptoms of heartburn, acid indigestion, and upset stomach associated with excessive gastric acidity. magnesium carbonate is primarily used for its antacid properties, relieving symptoms of excess gastric acids, such as heartburn, acid indigestion, and upset stomach.
Frequency not defined
Aluminum
Constipation
Stomach cramps
Vomiting
Hypophosphatemia
Osteomalacia
Chalky taste
Fecal impaction
Nausea
Aluminum intoxication
Magnesium
Hypermagnesemia
Diarrhea
Black box warning:
None
Contraindications/caution:
Contraindications:
Hypersensitivity
Caution:
Pregnancy consideration: C
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Pharmacodynamics:
Pharmacokinetics:
Absorption
aluminum hydroxide/magnesium carbonate is poorly absorbed from the gastrointestinal tract. It remains primarily in the gut and does not enter the systemic circulation to a significant extent.
Distribution
Since aluminum hydroxide is minimally absorbed, it does not undergo significant distribution within the body. Similarly, magnesium carbonate does not distribute extensively in the body when not absorbed.
Metabolism
aluminum hydroxide is not metabolized in the body. It remains in its unchanged form. magnesium carbonate does not undergo significant metabolism. It is metabolized to magnesium ions, which can participate in various biochemical processes in the body.
Elimination and Excretion
Unabsorbed aluminum hydroxide is excreted primarily through the feces. The kidneys primarily excrete any absorbed aluminum in individuals with normal renal function. Unabsorbed magnesium carbonate is eliminated in the feces. magnesium ions that are absorbed may be excreted via the kidneys.
Administration:
Patient information leaflet
Generic Name: aluminum hydroxide/magnesium carbonate
Why do we use aluminum hydroxide/magnesium carbonate?
aluminum hydroxide/magnesium carbonate combination is commonly used as an over-the-counter medication for treating symptoms related to excessive stomach acid, such as heartburn, acid indigestion, and upset stomach.
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