A Milestone Moment: FDA Approves Addyi® for Hypoactive Sexual Desire Disorder in Postmenopausal Women
December 17, 2025
Brand Name :
No Data Available.
Synonyms :
Class :
antiarrhythmics
Dosage Forms & Strengths
Tablet
50mg
100mg
150mg
100 - 300
mg/day
Orally
every 8 to 12 hours
Dosage Forms & Strengths
Tablet
50mg
100mg
150mg
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents
It may enhance QTc interval when combined with lithium
It may enhance the QTc interval when combined with efavirenz
QTc interval is increased both by lenvatinib and flecainide
may increase the QT-prolonging effect and enhance the risk of bradycardia, hypokalemia
may increase the QTc interval when combined
It may diminish the excretion when combined with alkalinizing agents
It may diminish the excretion when combined with alkalinizing agents
It may diminish the excretion when combined with alkalinizing agents
It may diminish the excretion when combined with alkalinizing agents
It may diminish the excretion when combined with alkalinizing agents
flecainide: they may diminish the excretion of alkalinizing agents
flecainide: they may diminish the excretion of alkalinizing agents
flecainide: they may diminish the excretion of alkalinizing agents
flecainide: they may diminish the excretion of alkalinizing agents
flecainide: they may diminish the excretion of alkalinizing agents
when bromazepam and flecainide are used together, there is a potential reduction in the bromazepam's metabolism
When acetohexamide is used together with flecainide, this lead to reduction in acetohexamide’s metabolism
When flecainide is used together with somatotropin, this leads to a rise in flecainide metabolism
flecainide: they may enhance the serum concentration of CYP2D6 Inhibitors
flecainide: they may enhance the serum concentration of CYP2D6 Inhibitors
flecainide: they may enhance the serum concentration of CYP2D6 Inhibitors
flecainide: they may enhance the serum concentration of CYP2D6 Inhibitors
flecainide: they may enhance the serum concentration of CYP2D6 Inhibitors
flecainide: they may increase the CNS depressant effect of CNS Depressants
flecainide: they may increase the CNS depressant effect of CNS Depressants
flecainide: they may increase the CNS depressant effect of CNS Depressants
flecainide: they may increase the CNS depressant effect of CNS Depressants
flecainide: they may increase the CNS depressant effect of CNS Depressants
when both drugs are combined, there may be an increased risk or severity of QTC prolongation
fedratinib increases the effect of flecainide by altering the intestinal/ hepatic CYP2D6 enzyme metabolism
carbonic anhydrase inhibitors decrease the excretion of flecainide
may increase the level of effectiveness through P-glycoprotein MDR1 efflux transporter
glycopyrrolate inhaled and formoterol
may increase the QTc interval when combined
sodium bicarbonate: they may diminish the excretion of flecainide
the risk of QTc prolongation may be increased
the rate of metabolism may be altered
flecainide and azithromycin, if used in combination, increase the QTc interval
Adverse drug reactions:
Frequency Defined
>10%
Visual disturbances
Dizziness
1-10%
Arrhythmias
Edema
Asthenia
Palpitations
Fatigue
Tremors
Fever
Tachycardia
Sinus pause/arrest
Vomiting
Diarrhea
Dyspepsia
Anorexia
Rash
Diplopia
Hypoesthesia
Paresthesia
Paresis
Ataxia
Pregnancy warnings:
Pregnancy category: C
Breastfeeding warnings:
The release of the drug into the human breastmilk is known
Pregnancy Categories:
Patient Information Leaflet
Generic Name: flecainide
Pronunciation: FLEK-a-nide
Why do we use flecainide?
Flecainide belongs to the class antiarrhythmics used to treat atrial Fibrillation, atrial flutter, Wolff-Parkinson-White Syndrome, Paroxysmal Supraventricular Tachycardia, and Supraventricular Tachycardia.