Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Gondafon
Synonyms :
glymidine
Class :
Oral hypoglycemics
Brand Name :
Gondafon
Synonyms :
glymidine
Class :
Oral hypoglycemics
Dosage Forms & StrengthsÂ
TabletÂ
500 mgÂ
1 gmÂ
Indicated for Type-II DM
250 mg one-two times a day (i.e., prior to breakfast and if required another dose prior to meal)
Safety and efficacy not establishedÂ
Refer to adult dosingÂ
may increase the Glucose-lowering effect of SGLT2 Inhibitors
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
fibric acid derivatives increase the effect of hypoglycemia of sulfonylureas
fibric acid derivatives increase the effect of hypoglycemia of sulfonylureas
fibric acid derivatives increase the effect of hypoglycemia of sulfonylureas
fibric acid derivatives increase the effect of hypoglycemia of sulfonylureas
fibric acid derivatives increase the effect of hypoglycemia of sulfonylureas
When helometasone is used together with glymidine, this leads to elevated risk or seriousness of hyperglycemia
When glymidine is used together with diazoxide, this leads to reduction in therapeutic effectiveness of glymidine
methylprednisolone hemisuccinateÂ
When methylprednisolone hemisuccinate is aided with glymidine, this leads to elevated hyperglycemia risk
may enhance the hypoglycemic effect of antidiabetic agents
may enhance the hypoglycemic effect of antidiabetic agents
may enhance the hypoglycemic effect of antidiabetic agents
may enhance the hypoglycemic effect of antidiabetic agents
may enhance the hypoglycemic effect of antidiabetic agents
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
may increase the hypoglycaemic effect
it decreases the effect of antidiabetic drugs
may increase the hypoglycaemic effect
may diminish the therapeutic effect of corticosteroids
may increase the hypoglycemic effect of beta blockers
may enhance the effect of sulfonylureas
probenecid could potentially lead to an elevation in the concentration serum of sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
Actions and Spectrum:Â
glymidine, serves as a sulfonamide antidiabetic medication utilized for managing diabetes mellitus. Its action involves amplifying insulin secretion from the pancreas and augmenting tissue responsiveness to insulin.
Sharing structural similarities with sulfonylureas, researchers have examined its pharmacokinetics in both acute and chronic liver conditions. Categorized as an antidiabetic agent, it acts as an agonist for sulfonylurea receptors, pivotal in its effectiveness in diabetes management.Â
Frequency not definedÂ
HypoglycemiaÂ
Allergic reactionsÂ
Black Box Warning:Â
NoneÂ
Contraindication/Caution:Â
ContraindicationÂ
CautionÂ
Pregnancy consideration:Â Â
US FDA pregnancy category: Not assignedÂ
Lactation:  Â
Excreted into human milk: Not known.Â
Pregnancy category:Â
Pharmacology:Â
glymidine, is a sulfonamide antidiabetic drug used to treat diabetes mellitus. It functions by increasing insulin secretion from the pancreas and enhancing the sensitivity of tissues to insulin. Structurally related to sulfonylureas, its pharmacokinetics have been studied in acute and chronic liver diseases. This drug is classified as an antidiabetic agent and acts as a sulfonylurea receptor agonist, contributing to its efficacy in managing diabetes. Â
Pharmacodynamics:Â
Mechanism of action: glymidine is a sulfonamide antidiabetic drug related to sulfonylureas. Based on this class of drugs and general principles of antidiabetic mechanisms. glymidine is believed to exert its effects by:Â
Pharmacokinetics:Â
AbsorptionÂ
glymidine is likely absorbed from the gastrointestinal tract into the bloodstream, potentially through active transport mechanisms.Â
DistributionÂ
Once in the bloodstream, glymidine would be distributed throughout the body to target tissues such as the pancreas.Â
MetabolismÂ
glymidine may undergo hepatic metabolism, which could be enzymatically modified to inactive metabolites.Â
Elimination and ExcretionÂ
The drug and its metabolites are likely excreted primarily through the renal route and eliminated in urine. Some minor excretion through other pathways, like feces, might occur.Â
Administration:Â
Oral administrationÂ
glymidine is administered orally. It is rapidly and completely absorbed following the oral administration. The drug has a high protein binding rate of around 90%. glymidine is a sulfonamide antidiabetic drug, structurally related to sulfonylureas, used to treat diabetes mellitus.
It was introduced as a possible alternative to other hypoglycemic agents. A healthcare professional should determine the recommended dosage and usage based on individual patient needs and medical history.Â
Patient information leafletÂ
Generic Name: glymidineÂ
Why do we use glymidine?Â
glymidine is a sulfonamide antidiabetic drug used to lower blood glucose by enhancing insulin secretion from the pancreas and enhancing the sensitivity of peripheral tissues to insulin.
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