Microplastics and Misinformation: What Science Really Says
November 12, 2025
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Brand Name :
Raxone
Synonyms :
idebenone
Class :
Antioxidants Benzoquinones
Dosage forms and strengths
Oral Tablet (Film-coated)
150 mg
The suggested dose is 300 mg thrice daily orally
(complete day dose is 900 mg)
Dosage forms and strengths
Oral Tablet (Film-coated)
150 mg
Children more than 12 years of age:
The suggested dose is 300 mg thrice daily orally
(complete day dose is 900 mg)
Refer adult dosing
it may diminish the excretion rate when combined with permethrin, resulting in an enhanced serum level
ampicillin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
amrinone has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
antipyrine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
antrafenine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
apremilast has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
arformoterol has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
atazanavir has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
atomoxetine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
baclofen has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
bacitracin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
azelaic acid has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
azathioprine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
benoxaprofen has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
benzatropine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
benzydamine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
bepotastine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
brivaracetam has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
bromazepam has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
budesonide has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
bupropion has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
buspirone has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
butabarbital has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
canagliflozin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
carbidopa has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
carboplatin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
carmustine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefadroxil has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefalotin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefapirin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefazolin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefdinir has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefmetazole has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefonicid has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefotaxime has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefotiam has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefoxitin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cefprozil has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
ceftazidime has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
ceftizoxime has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
ceftolozane has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
celecoxib has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cephalexin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cetirizine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
chloroquine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
chlorpropamide has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
cimetidine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
ciprofloxacin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
clonazepam has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
desipramine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
desmopressin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
desvenlafaxine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
diazepam has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
diclofenac has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
dimercaprol has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
dobutamine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
dopamine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
duloxetine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
estazolam has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
estradiol has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
ethambutol has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
etodolac has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
fenbufen has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
fenofibrate has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
fenoprofen has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
abacavir has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
aceclofenac has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
acemetacin has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
acetaminophen has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
acetylsalicylic acid has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
aclidinium has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
acyclovir has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
amphetamine has the potential to reduce the rate of excretion of idebenone, leading to an elevation in levels of serum
Actions and Spectrum:
Action:
idebenone is a potent antioxidant performing a pivotal function in safeguarding cells and tissues from harmful effects of oxidative stress. It neutralizes harmful free radicals which can cause cellular damage and contribute to various health conditions.
Spectrum:
idebenone has been researched as a potential therapeutic option for neurodegenerative conditions like Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. Its potential benefits include safeguarding of nerve cells against harm and enhances cognitive abilities.
Frequency not defined
Chromaturia
Bronchitis
Back pain
Azotaemia
Anorexia
Anaemia
Agranulocytosis
Agitation
Black Box Warning:
None
Contraindication/Caution:
Includes known allergies or hypersensitivity.
Pregnancy warnings:
Pregnancy category: N/A
Lactation: contraindicated
Pregnancy Categories:
Pharmacology:
Pharmacodynamics:
It can reduce oxidative stress by neutralizing free radicals and reactive oxygen species thereby it protects cells from damage which are caused by oxidative stress that implicates in various diseases and aging processes.
Pharmacokinetics:
Absorption
low oral bioavailability.
Distribution
Binds to plasma proteins to some extent which can affect distribution in bloodstream.
Metabolism
Metabolized into various metabolites and involves reducing the quinone group to form hydroquinone.
Excretion and Elimination
The metabolites are excreted through urine and feces.
Administration:
The route of administration is oral.
Patient information leaflet
Generic Name: idebenone
Why do we use idebenone?
idebenone addresses neurodegenerative conditions like Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. It may help to improve cognitive function and slow down disease progression.
idebenone has shown promising effects in treating mitochondrial disorders including Leber’s hereditary optic neuropathy (LHON). It helps to improve mitochondrial function which is crucial for cell energy production.
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