Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Daypro
Synonyms :
oxaprozin
Class :
NSAIDs
Brand Name :
Daypro
Synonyms :
oxaprozin
Class :
NSAIDs
Dosage forms & Strengths:Â
TabletÂ
600 mgÂ
600
mg
Tablet
Orally 
every day
May be increased to 1200mg Orally Tablet every day in severe cases
Do not exceed 1,800 mg daily
Dosage forms & Strengths:Â
TabletÂ
600 mgÂ
Juvenile Rheumatoid ArthritisÂ
Age: > 6 years
wt (22 to 31 kg): 600 mg orally daily
wt (32 to 54 kg): 900 mg orally daily
wt (> 55 kg): 1200 mg orally daily
Juvenile Rheumatoid ArthritisÂ
Age: > 6 years
wt (22 to 31 kg): 600 mg orally daily
wt (32 to 54 kg): 900 mg orally daily
wt (> 55 kg): 1200 mg orally daily
Refer adult dosing
interaction with NSAIDs may lead to increased toxicity such as myelosuppression, renal toxicity, and GI toxicity
interaction with NSAIDs may lead to increased toxicity such as myelosuppression, renal toxicity, and GI toxicity
When oxaprozin is used together with sertraline, the risk or seriousness of bleeding may be enhanced
When oxaprozin is used together with bufexamac, this leads to enhanced risk or seriousness of adverse outcomes
When oxaprozin is used together with nifenazone, this leads to enhanced risk or seriousness of adverse events
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
may enhance the toxicity of the other through anti coagulation
anticoagulation is increased by oxaprozin and decreased by mistletoe. The interaction's effect is unclear; exercise caution
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
may enhance the CNS depressant effect
may enhance the CNS depressant effect
may enhance the CNS depressant effect
may enhance the CNS depressant effect
it may decrease the levels of serum concentration
Actions and Spectrum:
oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic (pain-relieving) and anti-inflammatory properties. It is commonly prescribed to alleviate symptoms associated with various conditions, such as arthritis, osteoarthritis, rheumatoid arthritis, and other musculoskeletal disorders.
The action of oxaprozin is attributed to its ability to inhibit the synthesis of prostaglandins, which are chemical messengers involved in inflammation, pain, and fever. Specifically, oxaprozin inhibits the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. By reducing prostaglandin levels, oxaprozin helps to alleviate pain and inflammation associated with various conditions.
Frequency defined
10%
Upper respiratory tract infectionÂ
<1%
PalpitationsÂ
Stevens-Johnson syndrome Â
Toxic epidermal necrolysisÂ
Cerebrovascular accidentÂ
Gastrointestinal hemorrhage Â
Agranulocytosis Â
Leukopenia Â
Thrombocytopenia Â
Hepatitis Â
AmblyopiaÂ
Acute renal failureÂ
BronchospasmÂ
Interstitial nephritisÂ
Black Box Warning:
None
Oxaprozin is contraindicated in patients hypersensitive to the active ingredient.Â
Pregnancy consideration:Â Â
Avoid using the drug during pregnancy.Â
Breastfeeding warnings:Â Â
No data is available regarding the excretion of the drug in breast milk.Â
Pregnancy category:Â
Pharmacology:
oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used to relieve pain and reduce inflammation in various conditions, such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Here is an overview of the pharmacology of oxaprozin
Pharmacodynamics:
Mechanism of Action: oxaprozin exerts its therapeutic effects by inhibiting the activity of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. COX enzymes are responsible for the production of prostaglandins, which are inflammatory mediators involved in pain and inflammation. By inhibiting COX enzymes, oxaprozin decreases the synthesis of prostaglandins, leading to reduced pain and inflammation.
Pharmacokinetics:
Absorption
oxaprozin is well absorbed from the gastrointestinal tract.
Distribution
It reaches peak plasma concentrations within 1 to 2 hours.
Metabolism
The drug is extensively bound to plasma proteins, primarily albumin. Oxaprozin undergoes hepatic metabolism, primarily via glucuronidation, to form inactive metabolites.
Elimination and excretion
The metabolites are mainly eliminated through the urine, with a small portion excreted in the feces.
Administration:
Patient information leafletÂ
Generic Name: oxaprozinÂ
Pronounced: OX-a-PROE-zinÂ
Why do we use oxaprozin?Â
oxaprozin is used primarily for its anti-inflammatory and analgesic (pain-relieving) properties. It belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). Here are some common reasons why oxaprozin may be prescribed:
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