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Brand Name :
Percogesic Maximum Strength Backache Relief, Mobidin, Doan's Extra Strength
Synonyms :
magnesium salicylate
Class :
Salicylates
Brand Name :
Percogesic Maximum Strength Backache Relief, Mobidin, Doan's Extra Strength
Synonyms :
magnesium salicylate
Class :
Salicylates
Dosage Forms & Strengths
Tablet
325mg
580mg
600mg
Indicated for Moderate to Mild Pain:
Two tablets orally four times a day when necessary
Do not exceed eight tablets in 24 hours
Dosage Forms & Strengths
Tablet
325mg
580mg
600mg
Indicated for Moderate to Mild Pain:
>12 years: 2 tablets orally four times a day when necessary.
<12 years: Safety and efficacy not established
Refer adult dosing
may diminish the serum concentration of polyvalent cation-containing products
may diminish the serum concentration of polyvalent cation-containing products
may enhance the serum concentration of magnesium salts
may increase the toxic effect of salicylates
may diminish the serum concentration of polyvalent cation-containing products
may enhance the hypermagnesemic effect of magnesium salts
may diminish the serum concentration of polyvalent cation-containing products
may diminish the serum concentration of polyvalent cation-containing products
may enhance the CNS depressant effect of magnesium salts
may diminish the serum concentration of magnesium salts
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
may diminish the serum concentration of magnesium salts
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may diminish the serum concentration of magnesium salts
may diminish the serum concentration of magnesium salts
may diminish the serum concentration of magnesium salts
may diminish the serum concentration of magnesium salts
may diminish the serum concentration of magnesium salts
may diminish the serum concentration of magnesium salts
may diminish the serum concentration of magnesium salts
bismuth subcitrate, metronidazole and tetracycline
may diminish the absorption of magnesium salts
may diminish the absorption of magnesium salts
may diminish the absorption of magnesium salts
may diminish the absorption of magnesium salts
may diminish the absorption of magnesium salts
may increase the anti-coaugulant effect of salicylates
may increase the anti-coaugulant effect of salicylates
may increase the anti-coaugulant effect of salicylates
may increase the anti-coaugulant effect of salicylates
may increase the anti-coaugulant effect of salicylates
measles, mumps, rubella, and varicella vaccine, live (Rx)
may increase the toxic effect of salicylates
measles mumps and rubella vaccine, live
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
smallpox (vaccinia) vaccine, live
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may diminish the serum concentration of salicylates
may diminish the serum concentration of magnesium salts
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may increase the toxic effect of salicylates
may increase the hypoglycemic effect of salicylates
may increase the hypoglycemic effect of salicylates
may increase the hypoglycemic effect of salicylates
may increase the hypoglycemic effect of salicylates
may increase the hypoglycemic effect of salicylates
may enhance the serum concentration of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the nephrotoxic effect of salicylates
may enhance the toxic effect of salicylates
may enhance the toxic effect of salicylates
may enhance the toxic effect of salicylates
may enhance the toxic effect of salicylates
may enhance the toxic effect of salicylates
may diminish the therapeutic effect of salicylates
may diminish the therapeutic effect of salicylates
may diminish the therapeutic effect of salicylates
may increase the neuromuscular blocking effect of magnesium salts
may increase the neuromuscular blocking effect of magnesium salts
may increase the neuromuscular blocking effect of magnesium salts
may increase the neuromuscular blocking effect of magnesium salts
may increase the neuromuscular blocking effect of magnesium salts
choline magnesium trisalicylate
may enhance the anticoagulant effect of salicylates
may enhance the toxic effect of salicylates
may decrease the serum concentration and decrease in the efficacy
Actions and Spectrum:
Frequency not defined
Contraindications/caution:
Contraindications:
magnesium salicylate is contraindicated in certain situations and individuals, including:
Caution:
Several cautions should be taken into account when using magnesium salicylate, including:
Pregnancy consideration: C
Lactation: Excretion of the drug in human breast milk is known
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Pharmacodynamics:
Pharmacokinetics:
Absorption
magnesium salicylate is absorbed rapidly, with a peak plasma time of approximately 1.5 hours for its active metabolite, salicylic acid.
Distribution
magnesium salicylate is highly protein-bound, with 50-90% of the drug binding to plasma proteins.
Metabolism
magnesium salicylate is converted to salicylic acid in the bloodstream, which is then metabolized to salicyluric acid and salicyl phenolic glucuronide by enzymes in the liver.
Elimination and Excretion
The half-life of salicylic acid, the active metabolite of magnesium salicylate, is approximately 2 hours. The drug is eliminated primarily through the urine
Administration:
magnesium salicylate is typically administered orally in tablets, capsules, or liquid suspension. The medication is usually taken with food or milk to reduce the risk of stomach upset.
The dose and frequency of magnesium salicylate administration will depend on the treatment condition, the patient’s age and weight, and other factors.
Patient information leaflet
Generic Name: magnesium salicylate
Pronunciation: [ mag-NEE-zee-um-sa-LIS-i-late]
Why do we use magnesium salicylate?
magnesium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used to relieve pain and inflammation associated with a variety of conditions, including:
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