Long COVID Patterns in the RECOVER-Adult Study
November 21, 2025
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Brand Name :
Triple Antibiotic Ointment, Neosporin Original Ointment
Synonyms :
neomycin/polymyxin B/bacitracin topical
Class :
Antibacterials, Topical
Brand Name :
Triple Antibiotic Ointment, Neosporin Original Ointment
Synonyms :
neomycin/polymyxin B/bacitracin topical
Class :
Antibacterials, Topical
Dosage forms & Strengths:
Adult:
topical ointment/cream
(3.5mg/5,000 units/400 units)/ gram
Dosage forms & Strengths:
topical ointment/cream
(3.5mg/5,000 units/400 units)/ gram
Refer to the adult dosing
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with colistimethate
lansoprazole, amoxicillin, and clarithromycin
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
there may be an increased risk of renal impairment
they increase the nephrotoxicity of other aminoglycosides
neomycin/polymyxin B/bacitracin topical
they increase the nephrotoxicity of other aminoglycosides
they increase the nephrotoxicity of other aminoglycosides
they increase the nephrotoxicity of other aminoglycosides
they increase the nephrotoxicity of other aminoglycosides
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
neomycin/polymyxin B/gramicidin ophthalmicÂ
may increase the nephrotoxic effect of Polymyxin B
they increase the nephrotoxicity of other aminoglycosides
neomycin/polymyxin B/bacitracin topical
they increase the nephrotoxicity of other aminoglycosides
they increase the nephrotoxicity of other aminoglycosides
they increase the nephrotoxicity of other aminoglycosides
they increase the nephrotoxicity of other aminoglycosides
it increases the nephrotoxicity of aminoglycosides
it increases the nephrotoxicity of aminoglycosides
aminoglycosides increase the effect of neuromuscular blockage of mecamylamine
the adverse/toxic effects of aminoglycosides may be heightened by ataluren
the nephrotoxic effects of aminoglycosides may be enhanced by mannitol
may enhance the renal tubular clearance for anionic drug competition
aminoglycosides increase the effect of hypocalcemia of bisphosphonate derivatives
aminoglycosides increase the effect of hypocalcemia of bisphosphonate derivatives
aminoglycosides increase the effect of hypocalcemia of bisphosphonate derivatives
aminoglycosides increase the effect of hypocalcemia of bisphosphonate derivatives
aminoglycosides increase the effect of hypocalcemia of bisphosphonate derivatives
may diminish the concentration of serum when combined with cardiac glycosides
may diminish the concentration of serum when combined with cardiac glycosides
may diminish the concentration of serum when combined with cardiac glycosides
may have an increased therapeutic effect when combined with neuromuscular blocking drugs
may have an increased therapeutic effect when combined with neuromuscular blocking drugs
may have an increased therapeutic effect when combined with neuromuscular blocking drugs
may have an increased therapeutic effect when combined with neuromuscular blocking drugs
may have an increased therapeutic effect when combined with neuromuscular blocking drugs
may have an increased therapeutic effect when combined with neuromuscular-blocking agents
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may diminish the therapeutic effect of drug
may diminish the therapeutic effect of drug
may diminish the therapeutic effect of drug
may reduce the rate of excretion of aminoglycosides
may reduce the rate of excretion of aminoglycosides
may reduce the rate of excretion of aminoglycosides
may reduce the rate of excretion of aminoglycosides
may reduce the rate of excretion of aminoglycosides
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cyclosporine
Penicillins: they may diminish the serum concentration of aminoglycosides
amoxicillin and clavulanate potassium
Penicillins: they may diminish the serum concentration of aminoglycosides
Penicillins: they may diminish the serum concentration of aminoglycosides
Penicillins: they may diminish the serum concentration of aminoglycosides
Penicillins: they may diminish the serum concentration of aminoglycosides
may reduce the therapeutic effect of typhoid Vaccine
it increases the nephrotoxicity of aminoglycosides
it increases the nephrotoxicity of aminoglycosides
it increases the effect of neuromuscular blockage of aminoglycosides
they increase the effect of nephrotoxicity of aminoglycosides
they increase the effect of nephrotoxicity of aminoglycosides
they increase the effect of nephrotoxicity of aminoglycosides
they increase the effect of nephrotoxicity of aminoglycosides
they increase the effect of nephrotoxicity of aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased adverse/toxic effect when combined with aminoglycosides
may have an increased adverse/toxic effect when combined with aminoglycosides
may have an increased adverse/toxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may diminish the concentration of serum when combined with aminoglycosides
may diminish the concentration of serum when combined with aminoglycosides
may diminish the serum concentration when combined with aminoglycosides
may diminish the serum concentration when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
meningococcal A C Y and W-135 diphtheria conjugate vaccine
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
may increase the nephrotoxic effect of cephalosporins
aminoglycosides may intensify the neuromuscular-blocking effect of botulinum toxin-containing products
aminoglycosides' nephrotoxic effect may be intensified by amphotericin B
aminoglycosides may augment the ototoxic effect of carboplatin, particularly with higher doses of carboplatin
may diminish the excretion when combined with aminoglycosides
Actions and Spectrum:
Spectrum:
>10%:
Allergic contact dermatitis (60%)
Contraindication/Caution:
Contraindications:
Cautions:
Pregnancy consideration:
A pregnant woman should take the treatment only if highly required.
Breastfeeding warnings:
The excretion of the drug in breast milk is unknown.
Pregnancy category:
Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology
Pharmacodynamics:
Pharmacokinetics:
The antibiotics in neomycin/polymyxin B/bacitracin topical are poorly absorbed through the skin and mainly confined to the application site.
neomycin is primarily eliminated through the kidneys. At the same time, polymyxin B and bacitracin are primarily eliminated through the feces.
Administration:
neomycin/polymyxin B/bacitracin topical is applied to the skin as an ointment, cream, or lotion.
Patient information leaflet
Generic Name: neomycin/polymyxin B/bacitracin
Pronounced: NEE-oh-MYE-sin, POL-ee-MIX-in-B, BAS-i-TRAY-sin
Why do we use neomycin/polymyxin B/bacitracin?
neomycin/polymyxin B/bacitracin topical is used to treat skin infections caused by susceptible bacteria. It is commonly used to treat skin conditions such as impetigo, folliculitis, and infected wounds or cuts. The combination of three antibiotics in neomycin/polymyxin B/bacitracin topical provides broad-spectrum coverage against various bacteria commonly found on the skin.
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