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Brand Name :
Astepro,astelin nasal spray,
Synonyms :
Azelastine
Class :
Antihistamine
Brand Name :
Astepro,astelin nasal spray,
Synonyms :
Azelastine
Class :
Antihistamine
Dosage Forms & Strengths
Nasal spray
0.1%(137mcg/spray)
0.15%(205.5mcg/spray)
Astepro 0.15%-2 sprays in each nostril every day
Astelin 0.1%:1-2 sprays in each nostril every 12 hours
Astelin 0.1%-2 sprays in each nostril every 12 hours
Astepro 0.15%-2 sprays in each nostril every 12 hours
Dosage Forms & Strengths
Nasal spray
0.1%(137mcg/spray)
0.15%(205.5mcg/spray)
Astepro 0.15%:
<2 years: Safety and efficacy not established
2 to <6 years: 1 spray in each nostril every 12 hours
6 to 12 years: 1 spray in each nostril every 12 hours
>12 years: 2 sprays in each nostril every day
Astelin 0.1%:
<5 years: Safety and efficacy not established
5 to <12 years: 1 spray in each nostril every 12 hours
>12 years:1-2 sprays in each nostril every 12 hours
Astelin
<12 years: Safety and efficacy not established
>12 years:2 sprays in each nostril every 12 hours
<6 months: Safety and efficacy not established
Six months to <6 years: 1 spray in each nostril every 12 hours
6 to <12 years: 1 spray in each nostril every 12 hours
>12 years: 2 sprays in each nostril every day
Refer adult dosing
azelastine: it may increase the bradycardic effect of Bradycardia-Causing Agents
azelastine: it may increase the bradycardic effect of Bradycardia-Causing Agents
azelastine: it may increase the bradycardic effect of Bradycardia-Causing Agents
azelastine: it may increase the bradycardic effect of Bradycardia-Causing Agents
azelastine: it may increase the bradycardic effect of Bradycardia-Causing Agents
may increase the central nervous system depressant effect
azelastine may enhance the CNS depressant effect of CNS Depressants
azelastine may enhance the CNS depressant effect of CNS Depressants
azelastine may enhance the CNS depressant effect of CNS Depressants
azelastine may enhance the CNS depressant effect of CNS Depressants
azelastine may enhance the CNS depressant effect of CNS Depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the efficacy of CNS depressants
it increases the efficacy of CNS depressants
it increases the efficacy of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased CNS depressive effect when combined with CNS depressants
may have an increased CNS depressive effect when combined with CNS depressants
may have an increased CNS depressive effect when combined with CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
azelastine: they may increase the CNS depressant effect of CNS Depressants
azelastine: they may increase the CNS depressant effect of CNS Depressants
azelastine: they may increase the CNS depressant effect of CNS Depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
may increase the CNS depressant effect
hydrocodone/chlorpheniramine/pseudoephedrine
may increase the CNS depressant activity of CNS depressants
may increase the CNS depressant effect
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effects of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect
may increase the CNS depressant effect
may increase the CNS depressant effect
may increase the CNS depressant effect
may increase the CNS depressant effect
It may enhance sedation when combined with tramadol
Combining azelastine with pranlukast may cause a reduction in the azelastine metabolism
When domeperidone and azelastine is used together, this leads to reduction in the domeperidone’s metabolism
When azelastine is used together with fluconazole, this leads to reduction in the azelastine metabolism
When azelastine is used together with somatotropin, this leads to a rise in azelastine’s metabolism
When encainide is used together with azelastine, this leads to a rise in the encainide’s metabolism
When indisulam is used together with azelastine, this leads to a reduction in azelastine metabolism
the central nervous system depressant (CNS depressant) activities of azelastine may be increased when combined with remacemide
may increase the CNS depressant effect
the CNS depressant activity of azelastine may be decreased with dihydrocodeine
an increase in sedation can be seen if coadministered
the CNS depressant activity of azelastine may be increased
ramosetron may enhance the central nervous system depressant (cns depressant) activities of azelastine
when combined with danoprevir, the metabolism of azelastine can be reduced
pridinol: it may increase the central nervous system depressant activities of azelastine
the rate of metabolism of azelastine may be reduced
the risk of CNS depression may be increased
Frequency defined:
>10%
Headache
Rhinitis
Bitter taste
Cough
Somnolence
1-10%
Sneezing
Nausea
Rhinitis
Dizziness
Myalgia
Nasal burning
Dry mouth
Conjunctivitis
Fatigue
Pharyngitis
Increased weight
<1%
Breast pain
Contact dermatitis
Flushing
Hyperkinesia
Tachycardia
Vomiting
Amenorrhea
Constipation
Eczema
Glossitis
Post-marketing reports
Application site irritation
Chest pain
Dyspnea
Involuntary muscle contractions
Palpitations
Parosmia
Rash
Tolerance
Abnormal vision
Anaphylactoid reactions
Confusion
Facial edema
Nasal sores
Paresthesia
Pregnancy consideration: Insufficient data available
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient information leaflet
Generic Name: azelastine
Pronounced: (a-ZEL-as-teen)
Why do we use azelastine?
Azelastine is a medication that is used to treat symptoms of allergic rhinitis, such as sneezing, runny nose, and itchy or watery eyes. It is available as a nasal spray or eye drop and works by blocking the action of certain chemicals in the body that cause inflammation and allergy symptoms. Azelastine can be used to treat both seasonal and perennial allergic rhinitis. It may also be used to treat other types of allergies, such as allergic conjunctivitis (inflammation of the lining of the eye).
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