Microplastics and Misinformation: What Science Really Says
November 12, 2025
Brand Name :
Ultralanum plain
Synonyms :
Fluocortolona
Class :
Topical corticosteroids
Dosage Forms & StrengthsÂ
Cream/ointmentÂ
100mgÂ
Apply the required amount on the affected area topically, thrice daily
this medication should not be used on the face for over five days
Topical
Apply the required amount on the affected area topically, thrice daily
this medication should not be used on the face for over five days
Topical
Apply the required amount on the affected area topically, thrice daily
this medication should not be used on the face for over five days
Corticosteroid-responsive DermatosesÂ
- 100
Topical
0.25% caproate or 0.25% of pivalate or alcohol-containing cream to be applied on the affected area twice daily
Dosage Forms & StrengthsÂ
CreamÂ
Topical
3 times a day
Apply the required amount on the affected area topically thrice daily
Refer to adult dosingÂ
may increase the tacrolimus immunosuppressive effect
may decrease the antineoplastic effect of flurandrenolide
antacids: they may diminish the bioavailability of corticosteroids K1
antacids: they may diminish the bioavailability of corticosteroids K1
may increase the immunosuppressive effect of immunosuppressive agents
may increase the serum concentration
may increase the serum concentration
bazedoxifene/conjugated estrogens
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
the serum levels of fluocortolone may be raised when taken with abametapir
the risk of adverse effects may be increased when abatacept is taken with fluocortolone
the risk of irritation of the gastrointestinal tract can be seen if fluocortolone is taken with aceclofenac
the rate of metabolism of alectinib may be increased when taken with fluocortolone
the rate of metabolism of zonisamide may be increased when taken with fluocortolone
When fluocortolone is used in combination with profenamine, this leads to reduction in therapeutic effectiveness of profenamine
may increase the hypokalemic effect of amphotericin
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may enhance the adverse/toxic effect
may decrease the anti-neoplastic effect of each other when combined
When fluocortolone is used together with lomitapide, this leads to an enhancement in lomitapide’s metabolism
When fluocortolone is used together in combination with profenamine, this leads to reduction in therapeutic effectiveness of profenamine
When fluocortolone is aided by androstenediol, that promotes an increased risk of edema
the severity of hyperglycemia can be raised when fluocortolone is taken with acarbose
the anticoagulant property of acenocoumarol may be increased by fluocortolone
the rate of metabolism of fluocortolone may be reduced with amprenavir
the risk of weakness and myopathy may be increased if atracurium is taken with fluocortolone
the risk of adverse effects may be raised when fluocortolone is taken with baricitinib
the risk of infection can be raised if ublituximab is taken with fluocortolone
the risk of irritation of the gastrointestinal tract may be increased when fluocortolone is taken with valdecoxib
the rate of metabolism of zolpidem may be increased when taken with fluocortolone
Actions and spectrum:Â
As a corticosteroid, fluocortolone shows it’s action by glucocorticoid activity
Frequency not definedÂ
ItchingÂ
BurningÂ
Rashes on skinÂ
Skin irritationÂ
Cushing’s syndromeÂ
Irreversible telangiectasiaÂ
AtrophyÂ
Mild depigmentationÂ
Black Box Warning Â
Avoid contact with eyes.Â
Contraindication/Caution:Â
Contraindication:Â
Systemic infectionÂ
HypersensitivityÂ
Acne vulgarisÂ
Perioral dermatitisÂ
Untreated viral or fungal infectionsÂ
Pregnancy consideration:Â Â
USFDA pregnancy category: CÂ
Lactation:Â Â
Safety study is not available Â
Pregnancy category:Â Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus `in either the first or second trimester.Â
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
Pharmacology:Â
A glucocorticoid, fluocortolone, is administered orally for systemic use and topically for localized skin reactions.Â
Pharmacodynamics:Â
Pharmacokinetics:Â
Limited data availableÂ
AbsorptionÂ
DistributionÂ
MetabolismÂ
Elimination and excretionÂ
Half-life:Â
Administration:Â
Apply the required quantity of cream over the affected area.Â
Patient information leafletÂ
Generic Name: fluocortolone Â
Why do we use fluocortolone?Â
Fluocortolone is employed in the treatment of various skin infections like eczema and dermatitis. It is a corticosteroid therapy.Â