Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Brand Name :
Baycol
Synonyms :
cerivastatin
Class :
Lipid-Lowering Agents, Statins
Dosage Forms & StrengthsÂ
Tablet Â
0.2 mg Â
0.4 mg Â
Take a dose of 0.4 mg orally one time in a day in the evening
Not determined Â
Refer to adult dosingÂ
may decrease the therapeutic effect of Fc Receptor-Binding agents
may diminish the serum concentration when combined with HMG-CoA reductase inhibitors (statins)
may enhance the serum concentration of fostemsavir
may enhance the anticoagulant effect of Vitamin K Antagonists
may enhance the anticoagulant effect of Vitamin K Antagonists
may enhance the anticoagulant effect of Vitamin K Antagonists
may enhance the anticoagulant effect of Vitamin K Antagonists
may enhance the anticoagulant effect of Vitamin K Antagonists
When alprazolam and cerivastatin is used together, this leads to reduction in the alprazolam’s metabolism
When acetohexamide is used together with cerivastatin, this lead to reduction in acetohexamide’s metabolism
When cerivastatin is used together with norelgestromin, this leads to a rise in norelgestromin’s metabolism
When encainide is used together with cerivastatin, this leads to a reduction in the encainide’s metabolism
When cerivastatin is used together with adenine, this leads to a reduction in the cerivastatin's metabolism
cerivastatin: it may decrease the therapeutic efficacy of dextropropoxyphene
cerivastatin: it may decrease the excretion rate of daunorubicin
when both drugs are combined, there may be an increased metabolism of etoposide  
when both drugs are combined, there may be a high metabolism of paclitaxel  
may increase the anticoagulant effect of vitamin K antagonist
may increase the anticoagulant effect of vitamin K antagonist
may increase the anticoagulant effect of vitamin K antagonist
may increase the anticoagulant effect of vitamin K antagonist
may increase the anticoagulant effect of vitamin K antagonist
may enhance the serum concentration when combined
may increase the myopathic effect of HMG-CoA Reductase Inhibitors
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
the rate of metabolism of norethynodrel may be increased
When cerivastatin is used together with lomitapide, this leads to an enhancement in lomitapide’s metabolism
apalutamide: it may decrease the serum concentration of cerivastatin
apixaban: it may decrease the metabolism of cerivastatin
apomorphine: it may decrease the metabolism of cerivastatin
apremilast: it may enhance the metabolism of cerivastatin
aprepitant: it may reduce the metabolism of cerivastatin
brexpiprazole: it may decrease the metabolism of cerivastatin
brigatinib: it may enhance the metabolism of cerivastatin
brincidofovir: it may increase the serum concentration of cerivastatin
brivaracetam: it may increase the metabolism of cerivastatin
brompheniramine: it may increase the metabolism of cerivastatin
dasabuvir: it may decrease the excretion rate of cerivastatin
dasatinib: it may increase the metabolism of cerivastatin
deferasirox: it may decrease the metabolism of cerivastatin
delavirdine: it may decrease the metabolism of cerivastatin
etravirine: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
quinine: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
simvastatin: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
voxilaprevir: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
lercanidipine: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
ranolazine: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
ticagrelor: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
verapamil: it may enhance the serum concentration of HMG-CoA Reductase Inhibitors
they decrease the absorption of fibric acid derivatives
bezafibrate increases the effect of myopathy on HMG-CoA reductase inhibitors
Actions and SpectrumÂ
cerivastatin worked primarily by inhibiting the activity of the enzyme HMG-CoA reductase. This enzyme is responsible for the production of cholesterol in the liver. Â
cerivastatin reduces the synthesis of cholesterol in the liver. This, in turn, led to an increase in the number of LDL (low-density lipoprotein) receptors on the surface of liver cells. These receptors help the liver remove LDL cholesterol from the bloodstream.Â
Frequency not defined Â
Difficulty breathingÂ
Muscle aches, pain, or weaknessÂ
FeverÂ
Decreased urine Â
Blurred visionÂ
Closing of throatÂ
Swelling of lips, tongue, or faceÂ
Yellowing of skin or eyesÂ
Black Box WarningÂ
Rhabdomyolysis is a rare but serious condition in which muscle tissue breaks down, releasing a protein called myoglobin into the bloodstream. Myoglobin can damage the kidneys, leading to kidney failure, and can also result in other severe health issues.
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
cerivastatin’s mechanism of action is to inhibit the activity of the enzyme HMG-CoA reductase. This enzyme plays a crucial role in the liver’s production of cholesterol.Â
It reduces cholesterol synthesis to lower the levels of cholesterol in the liver.Â
PharmacodynamicsÂ
The inhibition of HMG-CoA reductase also led to an increase in the number of LDL receptors on the surface of liver cells. These receptors play an important role in removing LDL cholesterol from the bloodstream. Â
PharmacokineticsÂ
Absorption  Â
cerivastatin is rapidly absorbed from the gastrointestinal tract.Â
DistributionÂ
cerivastatin is distributed throughout the body and binds to plasma proteins.Â
MetabolismÂ
cerivastatin is metabolized in the liver.Â
Elimination and excretionÂ
cerivastatin is excreted in the urine.Â
AdministrationÂ
cerivastatin is taken orally in the form of tablets.Â
Patient information leafletÂ
Generic Name: cerivastatinÂ
Why do we use cerivastatin?Â
cerivastatin is used to lower cholesterol levels in patients with hypercholesterolemia and dyslipidemia. Â
It is primary used to reduce elevated levels of low-density lipoprotein (LDL) cholesterol.Â