Evaluating Blue Zones Demography in Response to Recent Critiques
January 6, 2026
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Priligy
Synonyms :
Dapoxetine
Class :
SSRI
Brand Name :
Priligy
Synonyms :
Dapoxetine
Class :
SSRI
Dosage Forms & Strengths:
Tablet
30 mg
60 mg
Drug-Induced Sexual Dysfunction
Take a dose of 30 mg orally one time daily
Dose Adjustments
Limited data is available
Pediatric
Not determined
Refer to the adult dosing
May have an increased serotonergic effect when combined with Serotonergic Agents
may enhance the concentration of serum when combined with dapoxetine
may enhance the concentration of serum when combined with dapoxetine
may enhance the concentration of serum when combined with dapoxetine
may enhance the concentration of serum when combined with dapoxetine
may enhance the concentration of serum when combined with dapoxetine
dapoxetine: they may enhance the serum concentration of CYP3A Inhibitors
dapoxetine: they may enhance the serum concentration of CYP3A Inhibitors
dapoxetine: they may enhance the serum concentration of CYP3A Inhibitors
dapoxetine: they may enhance the serum concentration of CYP3A Inhibitors
dapoxetine: they may enhance the serum concentration of CYP3A Inhibitors
dapoxetine: they may enhance the serum concentration of CYP2D6 Inhibitors
dapoxetine: they may enhance the serum concentration of CYP2D6 Inhibitors
dapoxetine: they may enhance the serum concentration of CYP2D6 Inhibitors
dapoxetine: they may enhance the serum concentration of CYP2D6 Inhibitors
dapoxetine: they may enhance the serum concentration of CYP2D6 Inhibitors
may enhance the serum concentration of CYP3A4 inhibitors
may enhance the serum concentration of CYP3A4 Inhibitors
dapoxetine: they may increase the toxic effect of mu-opioid receptor agonists
dapoxetine: they may increase the toxic effect of mu-opioid receptor agonists
may increase the orthostatic hypotensive effect of dapoxetine
may increase the orthostatic hypotensive effect of dapoxetine
may increase the orthostatic hypotensive effect of dapoxetine
may increase the orthostatic hypotensive effect of dapoxetine
may increase the orthostatic hypotensive effect of dapoxetine
may have an increased orthostatic hypotensive effect when combined with calcium channel blockers
may have an increased orthostatic hypotensive effect when combined with calcium channel blockers
may have an increased orthostatic hypotensive effect when combined with calcium channel blockers
may have an increased orthostatic hypotensive effect when combined with calcium channel blockers
may have an increased orthostatic hypotensive effect when combined with calcium channel blockers
may have an increased orthostatic hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased orthostatic hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased orthostatic hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased orthostatic hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased orthostatic hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased orthostatic hypotensive effect when combined with vasodilators
may have an increased orthostatic hypotensive effect when combined with vasodilators
may have an increased orthostatic hypotensive effect when combined with vasodilators
may have an increased orthostatic hypotensive effect when combined with vasodilators
may have an increased orthostatic hypotensive effect when combined with vasodilators
dapoxetine: they may increase the orthostatic hypotensive effect of Angiotensin II Receptor antagonists
dapoxetine: they may increase the orthostatic hypotensive effect of Angiotensin II Receptor antagonists
dapoxetine: they may increase the orthostatic hypotensive effect of Angiotensin II Receptor antagonists
dapoxetine: they may diminish the serum concentration of CYP3A4 Inducers
dapoxetine: they may diminish the serum concentration of CYP3A4 Inducers
dapoxetine: they may diminish the serum concentration of CYP3A4 Inducers
dapoxetine: they may diminish the serum concentration of CYP3A4 Inducers
dapoxetine: they may diminish the serum concentration of CYP3A4 Inducers
dapoxetine: they may increase the CNS depressant effect of CNS Depressants
dapoxetine: they may increase the CNS depressant effect of CNS Depressants
dapoxetine: they may increase the CNS depressant effect of CNS Depressants
dapoxetine: they may increase the CNS depressant effect of CNS Depressants
dapoxetine: they may increase the CNS depressant effect of CNS Depressants
the metabolism of dapoxetine may decrease when combined with amprenavir
nicorandil is used with caution when dapoxetine is prescribed, as it can have reduced orthostatic tolerance
amitriptylinoxide(Phase 4 Clinical Trials)
combining amitriptylinoxide with dapoxetine may increase the intensity of adverse effects
the intensity of adverse effects can be elevated when amobarbital is combined with dapoxetine
dapoxetine may enhance the intensity of orthostatic hypotensive effects of amoxapine
combining amphetamine with dapoxetine may increase the intensity of serotonin syndrome
dapoxetine may augment the intensity of orthostatic hypotensive and hypotensive effects of amyl nitrite
combining anagrelide with dapoxetine may increase the intensity of hemorrhage
the metabolism of dapoxetine may be increased when combined with anakinra
Actions and Spectrum:
Premature ejaculation is a condition in which sexual dysfunction occurs due to rapid ejaculation during sexual intercourse.
The drug is taken between 18 to 64 years old in men.
Frequency not defined
Serotonin syndrome
Headache
Tinnitus
Syncope
Agitation
Flatulence
Restlessness
Increased bleeding risk
Hyponatremia
Erectile dysfunction
Yawning
Vomiting
Diarrhea
Seizures
Dry mouth
Fatigue
Abdominal pain
Dyspepsia
Tremor
HTN
Paresthesia
Abnormal dreams
Anxiety
Sinus congestion
Black box warning:
The drug should be used on own, not with others.
Always take to the prescribed dosage and never exceed it.
Contraindication/Caution:
Contraindications:
Hypersensitivity
Women
Pediatrics
Cautions:
Renal impairment
Cardiovascular disorders
Epilepsy
Hepatic impairment
Drug interactions
Glaucoma
Pregnancy Warnings:
Pregnancy category: N/A
Lactation:
Excretion of the drug in human breast milk is unknown
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
<b>Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology:
Dapoxetine belongs to the class of selective serotonin reuptake inhibitors.
It increases the time taken for ejaculation during intercourse. For the best results, it is suggested to take dapoxetine a few hours before sexual activity.
Pharmacodynamics:
The mechanism of dapoxetine increases neurotransmitter activity linked to its inhibition of neuronal serotonin reuptake.
Pharmacokinetics:
Absorption
The plasma peak effect is achieved within 1 to 2 hours.
Distribution
The protein-bound ratio was found to be about 99.99%.
Metabolism
It undergoes extensive metabolism by various enzymes.
Elimination and Excretion
It is eliminated through urine.
Administration:
Dapoxetine is taken orally as prescribed.
Patient information leaflet:
Generic Name: dapoxetine
Why do we use dapoxetine?
Dapoxetine widely used in management of premature ejaculation in men.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
