Alcohol Consumption Emerges as a Key Risk Factor for Buccal Cancer in India
December 24, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Dalgan
Synonyms :
dezocine
Class :
Opioid Antagonists, Analgesics
Brand Name :
Dalgan
Synonyms :
dezocine
Class :
Opioid Antagonists, Analgesics
Dosage Forms & Strengths
Intravenous solution
5mg
10mg
20mg
Initially, administer 5mg intravenously every 2 to 4 hours or 10mg intramuscularly every 3 to 6 hours.
Maximum dose: Administer 10 mg intravenously and 20mg intramuscularly.
Safety and efficacy not established
Refer adult dosing
Concomitant administration with benzodiazepine agonists may enhance the risk of extreme sedation, respiratory depression, and coma
Concomitant administration with benzodiazepine agonists may enhance the risk of extreme sedation, respiratory depression, and coma
Concomitant administration with benzodiazepine agonists may enhance the risk of extreme sedation, respiratory depression, and coma
may have an increased Effect of CNS depressant when combined with serotonergic opioids
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
amoxicillin/omeprazole/rifabutin
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may reduce the analgesic effect of Opioid agonists
may reduce the analgesic effect of Opioid agonists
may reduce the analgesic effect of Opioid agonists
may reduce the analgesic effect of Opioid agonists
may reduce the therapeutic effect
may reduce the therapeutic effect
may reduce the therapeutic effect
it may diminish the therapeutic efficacy when combined with castor oil
When dezocine is used together with melitracen, this leads to enhanced risk or seriousness of CNS depression
When emylcamate is used together with dezocine, this leads to enhanced risk or seriousness of CNS depression
When dezocine is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
may enhance the CNS depressant effect
may enhance the CNS depressant effect
may enhance the CNS depressant effect
may enhance the CNS depressant effect
it may decrease the levels of serum concentration
Actions and Spectrum:
dezocine is an opioid analgesic that is used for pain management. It has both agonist and antagonist properties at opioid receptors. Its mechanism of action involves binding to and modulating various opioid receptors in the central nervous system.
The spectrum of activity for dezocine primarily focuses on managing moderate to moderately severe pain. Its combination of partial mu receptor agonism and kappa receptor antagonism provides effective pain relief while minimizing the risk of severe respiratory depression and other side effects commonly associated with more potent opioid agonists.
Frequency not defined
Mild gastrointestinal discomfort
Dizziness
Black box warning:
None
Contraindications/caution:
Contraindications:
Caution:
Pregnancy consideration: Insufficient data available
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
dezocine is an opioid analgesic with a complex pharmacological profile, combining the properties of both agonists and antagonists at various opioid receptors. It is used for pain management, particularly for moderate to severe pain.
Pharmacokinetics:
Absorption
Distribution
Metabolism
Elimination and Excretion
Administration:
Intravenous (IV) Administration:
Intramuscular (IM) Administration:
Subcutaneous (SC) Administration:
Patient information leaflet
Generic Name: dezocine
Why do we use dezocine?
dezocine is primarily used to manage moderate to moderately severe pain. It is an opioid analgesic with a unique pharmacological profile, combining partial agonist and antagonist properties at different opioid receptors.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
