Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Dalgan
Synonyms :
dezocine
Class :
Opioid Antagonists, Analgesics
Brand Name :
Dalgan
Synonyms :
dezocine
Class :
Opioid Antagonists, Analgesics
Dosage Forms & StrengthsÂ
Intravenous solutionÂ
5mgÂ
10mgÂ
20mgÂ
Initially, administer 5mg intravenously every 2 to 4 hours or 10mg intramuscularly every 3 to 6 hours.
Maximum dose: Administer 10 mg intravenously and 20mg intramuscularly.
Safety and efficacy not establishedÂ
Refer adult dosingÂ
Concomitant administration with benzodiazepine agonists may enhance the risk of extreme sedation, respiratory depression, and coma
Concomitant administration with benzodiazepine agonists may enhance the risk of extreme sedation, respiratory depression, and coma
Concomitant administration with benzodiazepine agonists may enhance the risk of extreme sedation, respiratory depression, and coma
may have an increased Effect of CNS depressant when combined with serotonergic opioids
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may have an increased CNS depressant effect when combined with opioid agonists
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
amoxicillin/omeprazole/rifabutin
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may reduce the analgesic effect of Opioid agonists
may reduce the analgesic effect of Opioid agonists
may reduce the analgesic effect of Opioid agonists
may reduce the analgesic effect of Opioid agonists
may reduce the therapeutic effect
may reduce the therapeutic effect
may reduce the therapeutic effect
it may diminish the therapeutic efficacy when combined with castor oil
When dezocine is used together with melitracen, this leads to enhanced risk or seriousness of CNS depression
When emylcamate is used together with dezocine, this leads to enhanced risk or seriousness of CNS depression
When dezocine is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may enhance the QTc-prolonging effect
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
it may increase the levels of serum concentration
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
it may decrease the levels of serum concentration
may enhance the CNS depressant effect
may enhance the CNS depressant effect
may enhance the CNS depressant effect
may enhance the CNS depressant effect
it may decrease the levels of serum concentration
Actions and Spectrum:Â
dezocine is an opioid analgesic that is used for pain management. It has both agonist and antagonist properties at opioid receptors. Its mechanism of action involves binding to and modulating various opioid receptors in the central nervous system.Â
The spectrum of activity for dezocine primarily focuses on managing moderate to moderately severe pain. Its combination of partial mu receptor agonism and kappa receptor antagonism provides effective pain relief while minimizing the risk of severe respiratory depression and other side effects commonly associated with more potent opioid agonists.Â
Frequency not definedÂ
Mild gastrointestinal discomfort Â
DizzinessÂ
Black box warning:Â
NoneÂ
Contraindications/caution:Â
Contraindications:Â
Caution:Â
Pregnancy consideration: Insufficient data availableÂ
Lactation: Excretion of the drug in human breast milk is unknownÂ
Pregnancy category:Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this categoryÂ
Pharmacology:Â
dezocine is an opioid analgesic with a complex pharmacological profile, combining the properties of both agonists and antagonists at various opioid receptors. It is used for pain management, particularly for moderate to severe pain. Â
Pharmacokinetics:Â
AbsorptionÂ
DistributionÂ
MetabolismÂ
Elimination and ExcretionÂ
Administration:Â
Intravenous (IV) Administration:Â
Intramuscular (IM) Administration:Â
Subcutaneous (SC) Administration:Â
Patient information leafletÂ
Generic Name: dezocineÂ
Why do we use dezocine?Â
dezocine is primarily used to manage moderate to moderately severe pain. It is an opioid analgesic with a unique pharmacological profile, combining partial agonist and antagonist properties at different opioid receptors. Â
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