A Framework for Fitness-for-Purpose and Reuse in Computational Phenotyping
November 17, 2025
Brand Name :
Flunarin, Fluner, Zerograin, Migon, Migranex, Grenil-F, Migarid, Profigran
Synonyms :
flunarizine
Class :
Calcium channel blockers and antihypertensives
Dosage Forms & StrengthsÂ
Capsule, Oral:Â
5 mgÂ
5 - 10
mg
Orally 
once a day
Note: allow 2 consecutive medication-free days each week
No safe and efficacious dosing instructions found Â
Refer to adult dosingÂ
may increase the central nervous system depressant effect
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
it increases the effect of CNS depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
CNS depressants increase the efficacy of flunarizine
CNS depressants increase the efficacy of flunarizine
CNS depressants increase the efficacy of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressive effect when combined with flunarizine
may have an increased CNS depressive effect when combined with flunarizine
may have an increased CNS depressive effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
may have an increased CNS depressant effect when combined with flunarizine
It may increase the CNS depressant effect when combined with CNS Depressants
flunarizine: they may increase the CNS depressant effect of CNS Depressants
flunarizine: they may increase the CNS depressant effect of CNS Depressants
flunarizine: they may increase the CNS depressant effect of CNS Depressants
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
CNS depressants increase the effect of flunarizine
may enhance the constipating effect of opioid agonist
may increase the CNS depressant effect
may increase the CNS depressant effects of CNS depressants
may increase the CNS depressants effects of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
promethazine/dextromethorphanÂ
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
acetaminophen/doxylamine/dextromethorphanÂ
may increase the CNS depressant effect CNS Depressants
CNS Depressants may enhance the CNS depressant effect of flunarizine
CNS Depressants may enhance the CNS depressant effect of flunarizine
CNS Depressants may enhance the CNS depressant effect of flunarizine
CNS Depressants may enhance the CNS depressant effect of flunarizine
CNS Depressants may enhance the CNS depressant effect of flunarizine
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
it increases the efficacy of antihypertensive agents
it increases the efficacy of antihypertensive agents
it increases the efficacy of antihypertensive agents
it increases the efficacy of antihypertensive agents
it increases the efficacy of antihypertensive agents
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may have an increased therapeutic effect when combined with antihypertensive agents
may have an increased therapeutic effect when combined with antihypertensive agents
may have an increased therapeutic effect when combined with antihypertensive agents
may have an increased therapeutic effect when combined with antihypertensive agents
may have an increased therapeutic effect when combined with antihypertensive agents
It may enhance the metabolism when combined with dexamethasone
it may diminish the therapeutic efficacy when combined with castor oil
flunarizine: they may increase the therapeutic effect when combined with antihypertensive drugs
Combining flunarizine with pranlukast may cause a reduction in the flunarizine’s metabolism
The potential for increased CNS depression risk or seriousness occurs when flunarizine is used together with pinazepam
When flunarizine is used together with medazepam, the risk or seriousness of CNS depression is enhanced
The potential for CNS depression may enhanced when flunarizine is used together with fencamfamin
When flunarizine is used together with niaprazine, the risk or seriousness of CNS depression is enhanced
When flunarizine is used together with levosulpiride, the risk or seriousness of CNS depression is enhanced
When flunarizine is used together with somatotropin, this leads to a rise in flunarizine metabolism
flunarizine: they may enhance the serum concentration of CYP2D6 Inhibitors
flunarizine: they may enhance the serum concentration of CYP2D6 Inhibitors
flunarizine: they may enhance the serum concentration of CYP2D6 Inhibitors
flunarizine: they may enhance the serum concentration of CYP2D6 Inhibitors
flunarizine: they may enhance the serum concentration of CYP2D6 Inhibitors
flunarizine: they may diminish the serum concentration of CYP3A4 Inducers
flunarizine: they may diminish the serum concentration of CYP3A4 Inducers
flunarizine: they may diminish the serum concentration of CYP3A4 Inducers
flunarizine: they may diminish the serum concentration of CYP3A4 Inducers
flunarizine: they may diminish the serum concentration of CYP3A4 Inducers
acrivastine and pseudoephedrineÂ
may increase the CNS depressant effect of CNS depressants
may enhance the risk of hypoglycemia when combined with Flunarizine
Frequency Not defined:Â Â Â
AnxietyÂ
DizzinessÂ
Motor dysfunctionÂ
SedationÂ
Sleep disorderÂ
VertigoÂ
Skin rashÂ
Weight gainÂ
Menstrual diseaseÂ
MyalgiaÂ
weakness Â
Pregnancy consideration: Flunarizine is reported with adverse reactions in animal reproduction studies.Â
Lactation: excretion of flunarizine in breast milk is not known. Â
Pregnancy category:Â
Â
Patient information leafletÂ
Generic Name: FlunarizineÂ
Pronounced: flunarizine Â
Why do we use flunarizine?Â
Flunarizine is used for the prevention of migraines.Â