Performance Comparison of Microfluidic and Immunomagnetic Platforms for Pancreatic CTC Enrichment
November 15, 2025
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Brand Name :
Solu-medrol
Synonyms :
methylprednisolone hemisuccinate
Class :
Glucocorticoids
Brand Name :
Solu-medrol
Synonyms :
methylprednisolone hemisuccinate
Class :
Glucocorticoids
Dosage Forms & StrengthsÂ
Sterile powder for injectionÂ
500 mgÂ
1000mgÂ
Indicated for acute spinal cord injury
Initial dose: Administer 30mg/kg for 15 minutes intravenously
After 45 minutes give 5.4mg/kg/hour of continuous infusion for 24 hours
Motor recovery was higher and consistent in patients who started the treatment within 3 to 8 hours of injury to receive the same regimen uninterrupted for up to 48 hours
Dosage Forms & StrengthsÂ
Sterile powder for injectionÂ
500 mgÂ
1000mgÂ
In children and infants, dosage can be decreased to ensure the efficacy of volume dosages as per the need of each case
It should be based on severity and response of individuals, but not on age or weight
The pediatric dosage should not be less than 0.5mg/kg every 24 hours
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
may increase the levels of serum concentration
When methylprednisolone hemisuccinate is used together in combination with profenamine, this leads to reduction in therapeutic effectiveness of profenamine
When methylprednisolone hemisuccinate is aided by androstenediol, that promotes an increased risk of edema
When methylprednisolone hemisuccinate is aided with acarbose, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with acetohexamide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with albiglutide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with alogliptin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with bromocriptine, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with bexagliflozin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with canagliflozin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with ceritinib, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with chlorpropamide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with dapagliflozin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with disopyramide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with dulaglutide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with empagliflozin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with ertugliflozin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with exenatide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with gliclazide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with glimepiride, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with glipizide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with gliquidone, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with glyburide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with glymidine, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin aspart, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin degludec, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin detemir, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin glargine, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin glulisine, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin human, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin lispro, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with insulin pork, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with liraglutide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with lixisenatide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with mecasermin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with metformin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with miglitol, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with nateglinide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with pentamidine, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with phenformin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with pioglitazone, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with pramlintide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with quinine, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with rosiglitazone, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with semaglutide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with sitagliptin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with sotagliflozin, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with sulfadiazine, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with sulfamethoxazole, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with sulfisoxazole, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with tirzepatide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with tolazamide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with tolbutamide, this leads to elevated hyperglycemia risk
When methylprednisolone hemisuccinate is aided with vildagliptin, this leads to elevated hyperglycemia risk
Actions and Spectrum: Â
Actions: Â
Methylprednisolone hemisuccinate has an antiinflammatory effect through cellular mechanisms by inhibiting the movement of leukocytes along with fibroblasts, reversing endothelial cell permeability, and stabilizing intracellular structures like lysosomes. Thus, this activity contributes to the reduction of immune response as well as the inflammation processes in different conditions ranging from autoimmune diseases to allergies.Â
Muscle painÂ
Dizziness Â
Weakness Â
Black Box Warning Â
Severe neurologic effects Â
Contraindication/Caution: Â
Hypersensitivity Â
Systemic fungal infectionsÂ
Pregnancy & breastfeeding:Â
Pregnancy consideration:  Â
Pregnancy category– CÂ Â
Breastfeeding warnings:  Â
No data is available regarding the excretion of drugs in breast milk. Â
Pregnancy category: Â
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester. Â
Category B: There was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
 Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.  Â
 Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women. Â
Category N: No data for the drug under this category is available. Â
Pharmacology:Â Â
Methylprednisolone hemisuccinate suppresses inflammation by preventing the migration of leukocytes and fibroblasts, reverses capillary permeability, and stabilizes lysosomes at the cell level, leading to an inflammatory effect. The drug is used in autoimmune disorders and allergic reactions.Â
Pharmacokinetics: Â
AbsorptionÂ
It is rapidly converted to methylprednisolone, the active metabolite after IV administration.Â
DistributionÂ
Within the body tissues, the drug is distributed widely. Approximately 1.4 L/kg is the distribution volume. Â
MetabolismÂ
The metabolism occurs in liver.
Excretion and EliminationÂ
The drug along with metabolites are mostly excreted by the urine, but only some are found to be excreted in bowels.Â
Administration: Â
The drug is administered intravenously.Â
Patient information leaflet Â
Generic Name: methylprednisolone hemisuccinateÂ
Why do we use methylprednisolone hemisuccinate? Â
Suppression of the immune response can be utilised to treat a range of inflammatory disorders, therefore reducing inflammation and relieving symptoms. Â
The drug is used in various conditions Such as severe allergic reactions (anaphylaxis), aggravated episodes of Asthma and rheumatic diseases.Â
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