Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Rapifen, Alfenta
Synonyms :
alfentanil
Class :
Synthetic, Opioids
Brand Name :
Rapifen, Alfenta
Synonyms :
alfentanil
Class :
Synthetic, Opioids
Dosage forms & Strengths:Â
Injectable solutionÂ
0.5 mg/mÂ
8-75 mcg/kg intravenously, according to the duration of surgery
0.5 mg/ml intravenously as per the body weight
may diminish the serum concentration when combined with alfentanil
may diminish the serum concentration when combined with alfentanil
may diminish the serum concentration when combined with alfentanil
may diminish the serum concentration when combined with alfentanil
may diminish the serum concentration when combined with alfentanil
may enhance the concentration of serum when combined with alfentanil
may enhance the concentration of serum when combined with alfentanil
may enhance the concentration of serum when combined with alfentanil
may enhance the concentration of serum when combined with alfentanil
may enhance the concentration of serum when combined with alfentanil
alfentanil: they may enhance the serum concentration of CYP3A Inhibitors
alfentanil: they may enhance the serum concentration of CYP3A Inhibitors
alfentanil: they may enhance the serum concentration of CYP3A Inhibitors
alfentanil: they may enhance the serum concentration of CYP3A Inhibitors
alfentanil: they may enhance the serum concentration of CYP3A Inhibitors
may enhance the serum concentration of CYP3A4 inhibitors
may enhance the serum concentration of CYP3A4 inhibitors
may diminish the serum concentration of CYP3A4 Inducers
may enhance the serum concentration of CYP3A4 Inhibitors
may diminish the serum concentration of CYP3A4 Inducers
may enhance serum concentrations of the CYP3A4 Inhibitors
may have an increased CNS depression when combined with alfentanil
may have an increasingly adverse effects when combined with Alfentanil
may increase the risk of adverse effects when combined with each other
the effect of alfentanil is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
when both drugs are combined, there may be a decreased effect of alfentanil by affecting hepatic or intestinal enzyme cyp3a4 metabolism  
CYP3A strong enhancers of the small intestine may reduce the the bioavailability of alfentanil
alfentanil increases the effect of fedratinib by altering the intestinal/ hepatic CYP3A4 enzyme metabolism
azelastine may enhance the CNS depressant effect of CNS Depressants
it increases the effect of CNS depressants
CNS depressants increase the effect of paraldehyde
CNS depressants increase the CNS depressing effect of thalidomide
CNS depressants increase the effect of flunarizine
it may decrease by affecting the hepatic enzyme CYP3A4 metabolism
it increases the concentration of alfentanil in the serum
it increases the effect of CNS depressants
CNS depressants may enhance the CNS depressant effect of cannabinoid-Containing products
CNS depressants may enhance the CNS depressant effect of cannabinoid-Containing products
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with phenobarbital
It may enhance sedation when combined with a shepherd's purse
It may enhance sedation when combined with codeine
it may diminish the therapeutic efficacy when combined with castor oil
It may enhance sedation when combined with oxycodone
combining batefenterol with alfentanil can enhance the risk or seriousness of adverse events
it may enhance the sedation when combined with lofexidine
The effectiveness of guanoxan's antihypertensive properties could be diminished by the presence of alfentanil
Combining xamoterol with alfentanil may elevate the risk/seriousness of hypertension
When metixene and alfentanil are combined, the risk or seriousness of adverse events will rise
The potential for CNS depression may enhanced when alfentanil is used together with fencamfamin
Combining tegafur with alfentanil can reduce tegafur’s metabolism
alfentanil may intensify paraldehyde's CNS depressant effects
When alfentanil is used together with levosulpiride, the risk or seriousness of CNS depression is enhanced
when alfentanil is used together with niaprazine, the risk or seriousness of CNS depression is enhanced
When alfentanil is used together with hexoprenaline, the potential for hypertension to occur may be elevated
When domeperidone and alfentanil is used together, this leads to reduction in the domeperidone’s metabolism
When alfentanil is used together with melitracen, this leads to enhanced risk or seriousness of CNS depression
When alfentanil is used together with abediterol, this leads to enhanced risk or seriousness of hypertension
When ponesimod is used together with alfentanil, this leads to enhanced risk or seriousness of bradycardia
When emylcamate is used together with alfentanil, this leads to enhanced risk or seriousness of CNS depression
When azatadine is used together with alfentanil, this leads to enhanced risk or seriousness of adverse events
When alfentanil is used together with vilanterol, this leads to enhanced risk or seriousness of hypertension
When sertindole is used together with alfentanil, this leads to enhanced risk or seriousness of CNS depression
alfentanil: it may increase the bradycardic activities of lidoflazine
When alfentanil is used together with oleandomycin, this leads to enhanced concentration serum of alfentanil
When alfentanil is used together with patupilone, this leads to enhanced concentration serum of alfentanil
alfentanil: it may increase the risk or severity of CNS depression
alfentanil: it may increase the risk or severity of CNS depression
alfentanil: it may increase the risk or severity of CNS depression
alfentanil: it may increase the risk or severity of CNS depression
alfentanil: it may increase the risk or severity of CNS depression
When alfentanil is used together with ridaforolimus, this leads to enhanced concentration serum of alfentanil
When alfentanil is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
combining alfentanil with carbaspirin calcium may increase the chances of hypertension
combining imidazole salicylate with alfentanil may increase the likelihood of hypertension
benzquinamide in combination with alfentanil could raise the risk or degree of adverse reactions
the risk or extent of adverse effects can be raised when clidinium is combined with alfentanil
alfentanil: it may diminish the antihypertensive activities of phentolamine
When alfentanil is used together with diazoxide, this leads to reduction in diazoxide’s antihypertensive effects
it increases the effect or level of palbociclib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
lofexidine may enhance the CNS depressant effect of CNS depressants
when combined, it may increase sedation
may increase the CNS depressant effect
may enhance the activity
when combined, it may increase sedation
may increase the CNS depressant effect
may increase the CNS depressant effect
may increase the CNS depressant effect
may increase the sedative effect of CNS depressants
it increases the concentration of alfentanil in the serum
may increase the CNS depressant effect
may increase the risk or severity of adverse effects when combined
may increase the risk or severity of hypertension when combined
may enhance the risk or severity of hypertension when combined
may increase the risk or severity of hypertension when combined
may increase the risk of hypertension when combined
It may diminish the metabolism when combined with nilvadipine
an increase in sedation can be seen if coadministered
the risk of adverse effects may be increased
the serum levels of alfentanil may be increased
the serum levels of alfentanil may be increased
the therapeutic effect of Remikiren may be reduced
the antihypertensive activity of candesartan cilexetil may be reduced
the therapeutic activity of alfentanil may be reduced
the risk of CNS depression may be increased
the severity of central nervous system depression can be increased when alfentanil is taken with zotepine
when both drugs are combined, there may be an increased effect of alfentanil by affecting hepatic or intestinal enzyme cyp3a4 metabolism  
it increases the effect of CNS depressants
>10%:Â
ArrhythmiaÂ
Bradycardia Â
Chest wall rigidity Â
Hypertension Â
Nausea Â
Vomiting Â
TachycardiaÂ
1-10%:Â
Apnea Â
Blurred vision Â
Dizziness Â
Hypotension Â
Post-op respiratory depression Â
Skeletal muscle movements Â
Postoperative sedationÂ
<1%:Â
FlushingÂ
PruritisÂ
Warmness of faceÂ
UrticariaÂ
ComaÂ
DysphoriaÂ
EuphoriaÂ
AgitationÂ
SeizuresÂ
RestlessnessÂ
SedationÂ
VomitingÂ
SyncopeÂ
OliguriaÂ
BradycardiaÂ
Dry MouthÂ
TachycardiaÂ
Alfentanil is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients.Â
Pregnancy consideration:Â Â
Insufficient data is available regarding usage during pregnancy.Â
Breastfeeding warnings:Â Â
Use the drug with caution during lactation.Â
Pregnancy category:Â
Patient information leafletÂ
Generic Name: alfentanilÂ
Pronounced: al-fen-tan-ilÂ
Why do we use alfentanil?Â
Alfentanil belongs to the category of synthetic opioids. It helps to anesthetize the patient.
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