Long COVID Patterns in the RECOVER-Adult Study
November 21, 2025
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Brand Name :
Decabicin, Dikacine, Debekacyl, Ibekacin, Icacine, Klobamicina, Nipocin, Panimycin
Synonyms :
Class :
Antibiotics & Aminoglycoside
Brand Name :
Decabicin, Dikacine, Debekacyl, Ibekacin, Icacine, Klobamicina, Nipocin, Panimycin
Synonyms :
Class :
Antibiotics & Aminoglycoside
Dosage forms & Strengths
Injection, Solution (intravenous):
75 mg/1.5 ml
Solution drop, Ophthalmic:
0.3% solution (5 ml)
Note: The product is available in various countries, except the US.
Dibekacine Sulfate is used for the following infections and conditions caused by staphylococcus and gram-negative bacteria:
Usual dose range:
1 to 3 mg/kg/day IV in divided doses
2
drops
4 times a day
No data available
Refer to adult dosing
measles, mumps, rubella, and varicella vaccine, live (Rx)
may diminish the therapeutic effect
measles mumps and rubella vaccine, live
may diminish the therapeutic effect
may diminish the therapeutic effect
smallpox (vaccinia) vaccine, live
may diminish the therapeutic effect
may diminish the therapeutic effect
respiratory syncytial virus vaccine, adjuvanted
may decrease the therapeutic effect when combined with vaccine
respiratory syncytial virus (RSV) vaccine
may decrease the therapeutic effect when combined with vaccine
poliovirus vaccine, live, trivalent
may decrease the therapeutic effect when combined with vaccine
poliovirus vaccine inactivated
may decrease the therapeutic effect when combined with vaccine
may have an increased nephrotoxic effect when combined with aminoglycosides
neomycin/polymyxin B/bacitracin topical
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased nephrotoxic effect when combined with aminoglycosides
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may decrease the therapeutic effect when combined with bacillus clausii
sodium picosulfate, citric acid, and magnesium oxide
may decrease the therapeutic effect when combined with sodium picosulfate
may decrease the therapeutic effect when combined with typhoid vaccine
antibiotics: they may decrease the therapeutic effect of sodium picosulfuric acid
meningococcal A C Y and W-135 diphtheria conjugate vaccine
may decrease the therapeutic effect of Antibiotics
may decrease the therapeutic effect of Antibiotics
may decrease the therapeutic effect of Antibiotics
may decrease the therapeutic effect of Antibiotics
may decrease the therapeutic effect of Antibiotics
may diminish the serum concentration of pencillins
may decrease the therapeutic effect when combined with bcg
may decrease the therapeutic effect when combined with cholera vaccine
antibiotics decrease the efficacy of BCG intravesical
it decreases the efficacy of antibiotics
dibekacin may reduce the therapeutic effects of estetrol
furosemide may enhance the ototoxic adverse effects of dibekacin
interaction of dibekacin with medication or fluid that causes electrolyte abnormalities may lead to adverse effects such as arrhythmias, seizures, and renal impairment
interaction of dibekacin with medication or fluid that causes electrolyte abnormalities may lead to adverse effects such as arrhythmias, seizures, and renal impairment
dibekacin may reduce the therapeutic effects of cholera vaccine
may increase the serum concentration of Cardiac Glycosides
may increase the serum concentration of Cardiac Glycosides
may increase the serum concentration of Cardiac Glycosides
may increase the serum concentration of Cardiac Glycosides
may increase the serum concentration of Cardiac Glycosides
they increase the effect of hypocalcemia in bisphosphonate derivatives
they increase the effect of hypocalcemia in bisphosphonate derivatives
they increase the effect of hypocalcemia in bisphosphonate derivatives
they increase the effect of hypocalcemia in bisphosphonate derivatives
may enhance the hypocalcemic effect of bisphosphonate derivatives
may enhance the hypocalcemic effect of bisphosphonate derivatives
may enhance the hypocalcemic effect of bisphosphonate derivatives
may enhance the hypocalcemic effect of bisphosphonate derivatives
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
may enhance the therapeutic effect of neuromuscular-blocking agents
may enhance the therapeutic effect of neuromuscular-blocking agents
may enhance the therapeutic effect of neuromuscular-blocking agents
may enhance the therapeutic effect of neuromuscular-blocking agents
may enhance the therapeutic effect of neuromuscular-blocking agents
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may decrease the therapeutic effect when combined with immune checkpoint inhibitors
may decrease the therapeutic effect when combined with immune checkpoint inhibitors
may decrease the therapeutic effect when combined with immune checkpoint inhibitors
may enhance the hypocalcemic effect
may increase the therapeutic effect of neuromuscular-blocking agents
may increase the therapeutic effect of neuromuscular-blocking agents
may increase the therapeutic effect of neuromuscular-blocking agents
may increase the therapeutic effect of neuromuscular-blocking agents
may increase the therapeutic effect of neuromuscular-blocking agents
may increase the therapeutic effect of neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased hypoglycemic effect when combined with sulfonylureas
may have an increased hypoglycemic effect when combined with sulfonylureas
penicillins may decrease the serum concentration of Aminoglycosides
penicillins may decrease the serum concentration of Aminoglycosides
penicillins may decrease the serum concentration of Aminoglycosides
penicillins may decrease the serum concentration of Aminoglycosides
penicillins may decrease the serum concentration of Aminoglycosides
penicillins may decrease the serum concentration of aminoglycosides.
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may decrease the excretion of non-steroidal anti-inflammatory drugs
loop diuretics may increase the risk of adverse effect of aminoglycosides
loop diuretics may increase the risk of adverse effect of aminoglycosides
loop diuretics may increase the risk of adverse effect of aminoglycosides
may increase the nephrotoxic effect of aminoglycosides
may increase the nephrotoxic effect of aminoglycosides
may increase the nephrotoxic effect of aminoglycosides
may increase the nephrotoxic effect of cephalosporins
may increase the anticoagulant effect of cephalosporins
may decrease the excretion of nonsteroidal anti-inflammatory agents
may have an increased neuromuscular-blocking effect when combined with botulinum toxin-containing products
may enhance the nephrotoxicity of aminoglycosides
may decrease the therapeutic effect when combined with immune checkpoint inhibitors
may decrease the therapeutic effect when combined with immune checkpoint inhibitors
may decrease the therapeutic effect when combined with immune checkpoint inhibitors
may decrease the therapeutic effect when combined with lactobacillus and estriol
may have an increased nephrotoxic effect when combined with aminoglycosides
may increase the nephrotoxic effect of Amphotericin B
BCG Vaccine live: they may decrease the therapeutic effect of antibiotics
antibiotics decrease the efficacy of thiamine by altering the gut flora
Dibekacin binds permanently to the bacterial ribosome’s 30S component that inhibit protein synthesis in sensitive bacteria.
This interference leads to mRNA misinterpretation and ultimately bacterial cell death by blocking the start of translation and amino acid incorporation.
None
Contraindication:
Hypersensitivity
Caution:
Ototoxicity (ear damage)
Nephrotoxicity (kidney damage)
Neuromuscular Blockade
Pregnancy considerations: No data available regarding pregnancy considerations.
Lactation: No data available regarding the effects of dibekacin in lactation.
Pregnancy category:
It inhibits the synthesis of proteins by binding permanently to the 30S subunit of the bacterial ribosome. As a result of this binding, translation is disrupted and mRNA is misread, which leads to the bacterial cell dying and producing defective or nonfunctional proteins.
Dibekacin works particularly well against aerobic Gram-negative bacteria such as Pseudomonas aeruginosa.
Dibekacin is administered deep intramuscular in divided doses every 8 to 12 hours depending on the severity of infection, renal function, and plasma levels.
For serious systemic infections, it may be administered as slow IV injection over 3 to 5 minutes or as a diluted infusion over 30 to 60 minutes.
Patient information leaflet
Generic Name: dibekacin
Why do we use dibekacin?
Dibekacin is used predominantly to treat severe infections caused by Gram-negative bacilli.
It is also indicated to treat pneumonia and other respiratory tract infections in people infected with drug-resistant gram-negative bacteria.
Dibekacin is used in burn wound infections and post-operative infections suspected to be due to gram-negative bacilli.
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