Long COVID Patterns in the RECOVER-Adult Study
November 21, 2025
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Brand Name :
Mag-G
(United States) [OTC]Synonyms :
magnesium gluconate
Class :
Minerals and electrolytes
Brand Name :
Mag-G
(United States) [OTC]Synonyms :
magnesium gluconate
Class :
Minerals and electrolytes
Dosage Forms & Strength
Males: dose up to 400-420 mg by mouth once each day
Females: age 18 to 30
dose of 310 mg take one pill by mouth once each day
Pregnancy: dose of 350 mg take one pill by mouth once each day
Lactation: dose of 310 mg take one pill by mouth once each day
>30 years (Females)
dose of 320 mg per day
Pregnant women: dose of 360 mg per day
Lactating women: Â dose of 320 mg per day
Take 5 to 10 ml of liquid on first day
Take initial dose of 2 to 4 tablets on first day
Reduce intake if loose stool persists and titrate to higher dose until stool softens and remains soft
Renal Impairment
Creatinine clearance values <30 mL/min: decrease dose and monitor for hypermagnesemia
Dosage Forms & Strength
RDA
Age: <6 months
30 mg daily
Age: 6-12 months
75 mg daily
Age: 1-3 years
80 mg daily
Age: 3-8 years
130 mg daily
For <6 months:
Take dose of 30 mg in a day
For 6 to 12 months:
Take dose of 75 mg in a day
For 1 to 3 years:
Take dose of 80 mg in a day
For 3 to 8 years:
Take dose of 130 mg in a day
For 8 to 13 years:
Take dose of 240 mg in a day
For 13 to 18 years (Adolescent boys):
Take dose of 410 mg in a day
For 13 to 18 years (Adolescent girls):
Take dose of 360 mg in a day
For Pregnant women:
Take dose of 400 mg in a day
For Lactating women:
Take dose of 360 mg in a day
Renal Impairment
Creatinine clearance values <30 mL/min: decrease dose and monitor for hypermagnesemia
Refer adult dosing
bismuth subcitrate, metronidazole and tetracycline
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
may have a decreased serum concentration when combined with phosphate supplements
may have a decreased serum concentration when combined with phosphate supplements
may have a decreased serum concentration when combined with phosphate supplements
tetraferric tricitrate decahydrate
may have a decreased serum concentration when combined with phosphate supplements
may have a decreased serum concentration when combined with phosphate supplements
bismuth subcitrate, metronidazole and tetracycline
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
may reduce the levels of serum concentration of multivitamins
may reduce the level of serum concentration of quinolones
may reduce the level of serum concentration of quinolones
may diminish the absorption when combined with tetracyclines
magnesium salts: they may diminish the bioavailability of corticosteroids A1
magnesium salts: they may diminish the bioavailability of corticosteroids A1
magnesium salts: they may diminish the bioavailability of corticosteroids A1
magnesium salts: they may diminish the bioavailability of corticosteroids A1
magnesium salts: they may diminish the bioavailability of corticosteroids A1
magnesium salts: they may diminish the bioavailability of corticosteroids J3
magnesium salts: they may diminish the bioavailability of corticosteroids J3
magnesium salts: they may diminish the bioavailability of corticosteroids J3
magnesium salts: they may diminish the bioavailability of corticosteroids J3
magnesium salts: they may diminish the bioavailability of corticosteroids J4
magnesium salts: they may diminish the bioavailability of corticosteroids J4
magnesium salts: they may diminish the bioavailability of corticosteroids J4
magnesium salts: they may diminish the bioavailability of corticosteroids J4
magnesium salts: they may diminish the absorption of phosphate binders
magnesium Salts may decrease the serum concentration of Dolutegravir
magnesium Salts may decrease the serum concentration of quinolones
magnesium Salts may decrease the serum concentration of quinolones
may diminish the serum concentration of quinolones
may have an increased hypermagnesemic effect when combined with magnesium salts
may have a decreased absorption when combined with alpha-lipoic acid
may increase the serum concentration when combined with magnesium salts
may have a decreased serum concentration when combined with dolutegravir
may have a decreased serum concentration when combined with quinolones
may have a decreased serum concentration when combined with quinolones
bismuth subcitrate, metronidazole and tetracycline
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
acalabrutinib: they may diminish the serum concentration of magnesium salts
alfacalcidol: they may enhance the serum concentration of magnesium salts
atazanavir: they may diminish the absorption of magnesium salts
cefuroxime: they may diminish the serum concentration of magnesium salts
chloroquine: they may diminish the serum concentration of magnesium salts
dabigatran: they may diminish the serum concentration of magnesium salts
delavirdine: they may diminish the serum concentration of magnesium salts
eltrombopag: they may increase the hypermagnesemic effect of magnesium salts
fosinopril: they may increase the CNS depressant effect of magnesium salts
infigratinib: they may diminish serum concentrations of magnesium salts
may have an increased adverse effect when combined with vitamin D analogs
may diminish the serum concentration when combined with raltegravir
may have an increased CNS depressant effect when combined with gabapentin
may have a decreased serum concentration when combined with levothyroxine
may have a decreased serum concentration when combined with fluoride/multivitamins (with ADE)
may decrease the serum concentration of Polyvalent Cation Containing Products
levonorgestrel: they may diminish the serum concentration of magnesium salts
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may increase the effect of neuromuscular-blocking agents
may reduce the rate of absorption of tetracyclines
may reduce the rate of absorption of tetracyclines
may reduce the rate of absorption of tetracyclines
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
it may enhance the risk of side effects when combined with misoprostol
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased CNS depressant effect when combined with CNS depressants
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased CNS depressive effect when combined with CNS depressants
may have an increased CNS depressive effect when combined with CNS depressants
may have an increased CNS depressive effect when combined with CNS depressants
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
Actions and Spectrum:
magnesium gluconate works by replenishing magnesium levels in the body. magnesium is an essential mineral that plays a role n many bodily functions, including nerve and muscle function, blood pressure regulation, and the synthesis of DNA, RNA, and proteins.
magnesium gluconate is primarily used to prevent or treat low magnesium levels in the body. Low magnesium levels can be caused by a variety of factors, including dietary deficiencies, alcoholism, kidney disease, and certain medications. Symptoms of low magnesium levels may include muscle cramps, tremors, fatigue, and irregular heartbeat. magnesium gluconate is also sometimes used to treat constipation or heartburn
Frequency defined
Frequency Not Defined
Diarrhea
Bloating gas
Upset stomach
Black Box Warning:
magnesium gluconate does not have a black box warning. Black box warnings are the most serious type of warning issued by the US Food and Drug Administration (FDA), and they are used to highlight significant risks associated with a particular drug.
Contraindication/Caution:
Contraindications:
Hypersensitivity: magnesium gluconate should not be used by individuals who have a known hypersensitivity to magnesium or any of its ingredients.
Renal Failure: magnesium gluconate should be used with caution in individuals with renal failure, as excessive magnesium intake can lead to magnesium toxicity and further kidney damage.
Cautions:
Pregnancy and breastfeeding: Pregnant or breastfeeding women should use magnesium gluconate with caution, as excessive magnesium intake can harm the developing fetus or nursing infant.
Cardiovascular disease: magnesium gluconate may cause a decrease in blood pressure, so individuals with cardiovascular disease or low blood pressure should use it with caution.
Gastrointestinal issues: magnesium gluconate may cause gastrointestinal issues, such as diarrhea and nausea, in individuals with gastrointestinal issues or irritable bowel syndrome.
Other medications: magnesium gluconate may interact with certain medications, including antibiotics, diuretics, and some osteoporosis medications, so it’s important to talk to a healthcare provider before taking magnesium gluconate if you are currently taking any medications.
Pregnancy consideration:
Pregnancy category: elemental magnesium dietary reference intake during pregnancy is 350-400 mg per day for adult women
Lactation:
Distributed in breast milk, elemental magnesium dietary reference intake for breast feeding women is 310-360 mg per day for adult women
Pregnancy category:
Pharmacology:
magnesium gluconate is an oral mineral supplement that contains magnesium, an essential mineral that plays a role in many bodily functions. When taken orally, magnesium gluconate dissociates into magnesium ions in the gastrointestinal tract, which are then absorbed into the bloodstream. Magnesium ions are involved in many cellular processes, including nerve and muscle function, DNA synthesis, and energy metabolism.
Pharmacodynamics:
The pharmacodynamics of magnesium gluconate is related to the pharmacological effects of magnesium.
Magnesium plays a role in nerve function and can help regulate the activity of nerve cells. Magnesium is involved in muscle contraction and relaxation and can help prevent muscle cramps and spasms.
Magnesium can help regulate heart rhythm and can lower blood pressure in some individuals. Magnesium is involved in bone formation and can help maintain bone density. Magnesium is involved in energy metabolism and can help convert food into energy.
Pharmacokinetics:
Absorption
magnesium gluconate is absorbed in the gastrointestinal tract. The rate of absorption depends on the dosage form and the presence of food in the stomach. It is absorbed more slowly on an empty stomach and more rapidly when taken with food
Distribution
magnesium is distributed throughout the body, with the majority being stored in bone and muscle tissue. magnesium does not readily cross the blood-brain barrier.
Metabolism
magnesium is not metabolized by the body. It is eliminated primarily by the kidneys.
Elimination and Excretion
magnesium is eliminated from the body primarily through the kidneys. In individuals with renal impairment, elimination may be slower, leading to an increased risk of magnesium toxicity
Administration
magnesium gluconate is available in oral tablet or liquid form and is typically taken with food or as directed by a healthcare provider. The dosage and frequency of magnesium gluconate depend on the individual’s magnesium levels and underlying medical conditions.
The usual adult dose of magnesium gluconate for magnesium deficiency is 2.5 g to 4 g (1 to 2 tablets or teaspoons) per day, divided into 2 to 4 doses. The dosage may be adjusted based on the individual’s magnesium levels and response to treatment.
Do not take more than the recommended dose, as excessive magnesium intake can cause adverse effects such as diarrhea, nausea, and stomach upset.
Patient information leaflet
Generic Name: magnesium gluconate
Pronounced: mag-NEE-zhum-GLOO-koe-nate
Why do we use magnesium gluconate?
magnesium gluconate is available in tablet or liquid form and is typically taken with food or as directed by a healthcare provider. The dosage and frequency of magnesium gluconate depend on the individual’s magnesium levels and underlying medical conditions.
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