Performance Comparison of Microfluidic and Immunomagnetic Platforms for Pancreatic CTC Enrichment
November 15, 2025
Brand Name :
Noxivent
Synonyms :
nitric oxide
Class :
Vasodilating agent
Not indicatedÂ
Dosage forms & strengthsÂ
Respiratory inhalerÂ
800 ppmÂ
100 ppmÂ
Refer adult dosingÂ
may increase the toxic effect of Methemoglobinemia Associated Agents
may have an increasingly adverse effect when combined with methemoglobinemia agents
may have an increasingly adverse effect when combined with methemoglobinemia agents
may have an increasingly adverse effect when combined with methemoglobinemia agents
may have an increasingly adverse effect when combined with methemoglobinemia agents
may have an increasingly adverse effect when combined with methemoglobinemia agents
nitric oxide: they may increase the toxic effect of opioid drugs
nitric oxide: they may increase the toxic effect of opioid drugs
nitric oxide: they may increase the toxic effect of opioid drugs
nitric oxide: they may increase the toxic effect of opioid drugs
It may enhance the risk of adverse effects when combined with Radipharmaceuticals
It may enhance the risk of adverse effects when combined with Radipharmaceuticals
may increase the toxic effect of local anesthetics
may increase the toxic effect of Methemoglobinemia Associated Agents
may increase the adverse effect of Methemoglobinemia Associated Agents
may increase the adverse effect of Methemoglobinemia Associated Agents
may decrease the therapeutic effect when combined with Iobenguane Radiopharmaceutical Products
may decrease the therapeutic effect when combined with Iobenguane Radiopharmaceutical Products
may decrease the therapeutic effect when combined with Iobenguane Radiopharmaceutical Products
may decrease the therapeutic effect when combined with Iobenguane Radiopharmaceutical Products
may decrease the therapeutic effect when combined with Iobenguane Radiopharmaceutical Products
acyclovir leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
alclofenac leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
acetylsalicylic acid leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
aceclofenac leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
acemetacin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
aminophenazone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
amitriptyline leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
amphetamine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ampicillin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
antrafenine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
atazanavir leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
atomoxetine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
bacitracin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
baclofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
balsalazide leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
benorilate leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
benoxaprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
benzatropine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
benzydamine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
bleomycin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
bumadizone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
carbidopa leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
carboplatin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
carmustine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
carprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefaclor leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefadroxil leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefalotin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefamandole leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefapirin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefazolin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefditoren leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefepime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefmenoxime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefmetazole leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefonicid leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefoperazone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ceforanide leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefotaxime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefotetan leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefotiam leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefoxitin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefpiramide leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefpirome leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefpodoxime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefprozil leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefradine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ceftazidime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ceftibuten leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ceftizoxime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ceftobiprole leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ceftriaxone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cefuroxime leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cephalexin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cephaloglycin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cetirizine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cevimeline leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
chlorzoxazone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
choline magnesium trisalicylateÂ
choline magnesium trisalicylate leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cidofovir leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
clobazam leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
colistimethate leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cyanocobalamin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
cyclosporine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
daptomycin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
desmopressin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
dexibuprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
dexketoprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
dexrazoxane leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
diatrizoate leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
diclofenac leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
diflunisal leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
dihydrostreptomycin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
disopyramide leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
doxycycline leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ertapenem leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ethambutol leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
etodolac leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
etonogestrel leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
etoricoxib leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
fenbufen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
fenoprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
floctafenine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
floxuridine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
fluconazole leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
flurbiprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
fluvoxamine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
hydromorphone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ibuprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ibutilide leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
indomethacin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
isoxicam leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ketoprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
ketorolac leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
leuprolide leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
lithium citrate leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
lopinavir leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
loracarbef leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
lorazepam leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
lornoxicam leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
loxoprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
lumiracoxib leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
meclofenamic acid leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
mefenamic acid leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
meloxicam leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
mesalazine leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
metamizole leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
metformin leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
methadone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
methotrexate leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
milrinone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
nabumetone leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
Vasodilation: Nitric oxide is a potent vasodilator, relaxing smooth muscle cells within blood vessels, resulting in better oxygen delivery to tissues and increased blood flow.Â
Immune response: It’s involved in immune defense mechanisms, acting as a mediator in the immune response against pathogens and potentially modulating inflammation.Â
Frequency not defined Â
Unusual tirednessÂ
FaintnessÂ
Blurred visionÂ
ConfusionÂ
Trouble breathingÂ
DizzinessÂ
None Â
Hypersensitivity or allergic reactions: Individuals who have shown hypersensitivity or allergic reactions to nitric oxide or related compounds should not receive nitric oxide therapy due to the risk of severe allergic responses.Â
Pregnancy: The safety of nitric oxide during pregnancy has not been fully established. Its use during pregnancy should be carefully evaluated and weighed against potential risks to the fetus.Â
Hemodynamic instability: In patients with severe hypotension or unstable cardiovascular conditions, the use of nitric oxide might worsen the situation by causing further hemodynamic instability.Â
Certain bleeding disorders: Nitric oxide may increase the risk of bleeding in patients with certain bleeding disorders or those taking anticoagulant medications due to its vasodilatory effects.Â
Pregnancy category: AU TGA pregnancy category: B2
US FDA pregnancy category: CÂ
Lactation: Excreted into human milk is unknownÂ
Pregnancy Categories:        Â
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.Â
Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this category
Pharmacology: Nitric oxide is a small & extremely reactive molecule that functions as a signaling agent within the body.Â
Pharmacodynamics:Â Â
Nitric oxide primary action is vasodilation, achieved by activating soluble guanylate cyclase in smooth muscle cells, ultimately leading to increased cyclic guanosine monophosphate levels and muscle relaxation.Â
Pharmacokinetics:Â
AbsorptionÂ
Nitric oxide is readily absorbed in the lungs when inhaled, entering the bloodstream through diffusion.Â
In systemic circulation, nitric oxide binds to haemoglobin and other molecules, reducing its bioavailability.Â
DistributionÂ
Nitric oxide has a very short half-life in the blood, estimated at less than a second.Â
Its free diffusion allows it to quickly reach target tissues where it exerts its effects.Â
Once diffused into cells, nitric oxide interacts with specific molecular targets and is readily consumed in its actions.Â
MetabolismÂ
Unlike most drugs, nitric oxide isn’t metabolized by enzymes.Â
Instead, it reacts with oxygen and other reactive molecules, including superoxide, forming nitrates and nitrites.Â
These breakdown products can be further metabolized or excreted.Â
Excretion and EliminationÂ
Nitrates and nitrites, the main NO metabolites, are primarily excreted in urine.Â
Inhalation is the most common route for administering nitric oxide in clinical settings, particularly for respiratory conditions.
Generic Name: nitric oxideÂ
Why do we use nitric oxide? Â
Inhaled nitric oxide promotes vasodilation in the pulmonary circulation, helping patients with pulmonary hypertension and ARDS.Â