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Brand Name :
Zeposia
Synonyms :
ozanimod
Class :
Sphingosine 1-Phosphate Receptor Modulators
Brand Name :
Zeposia
Synonyms :
ozanimod
Class :
Sphingosine 1-Phosphate Receptor Modulators
Dosage forms & Strengths:Â
CapsuleÂ
0.23 mgÂ
0.46 mgÂ
0.92 mgÂ
Days 1-4: 0.23 mg orally daily
Days 5-7: 0.46 mg orally daily
Day 8 and following: 0.92 mg orally daily
Days 1-4: 0.23 mg orally daily
Days 5-7: 0.46 mg orally daily
Day 8 and following: 0.92 mg orally daily
Safety and efficacy are not seen in pediatrics.Â
Refer adult dosing
It may enhance toxicity when combined with inamrinone by sympathetic effects
It may enhance the toxicity effect when combined with tafamidis meglumine
ozanimod: they may increase the toxic effect of vaccines
measles, mumps, rubella, and varicella vaccine, live 
ozanimod: they may increase the toxic effect of vaccines
measles mumps and rubella vaccine, live
ozanimod: they may increase the toxic effect of vaccines
ozanimod: they may increase the toxic effect of vaccines
smallpox (vaccinia) vaccine, live
ozanimod: they may increase the toxic effect of vaccines
dengue vaccine efficacy will be reduced by ozanimod
when both drugs are combined, there may be an increased risk or severity of adverse effects   
when both drugs are combined, the metabolism of paclitaxel decreases when compared with ozanimod  
when both drugs are combined, there may be an increased risk or severity of adverse effects  
when both drugs are combined, there may be an increased risk of severe and potentially life-threatening infections   
when both drugs are combined, the risk or severity of adverse effects increases  
lapatinib and ozanimod increase the toxicity of one another when used simultaneously
When both drugs are combined, there may be an increased risk of severe and potentially life-threatening infections  
both the drugs, when used in combination, increase the effect of one another
it will increase the impact or level of regorafenib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
it enhances by affecting the hepatic enzyme CYP2D6 metabolism
measles, mumps, rubella and varicella vaccine, liveÂ
may increase the toxic effects of varicella virus containing vaccine
may enhance the serum concentration of CYP2C8 inhibitors
it increases the toxicity of serotonergic agents
it increases the effect of hypertension of sympathomimetics
it increases the effect of hypertension of sympathomimetics
it increases the effect of hypertension of sympathomimetics
it increases the effect of hypertension of sympathomimetics
it increases the effect of hypertension of sympathomimetics
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased hypertensive effect when combined with sympathomimetics
may have an increased hypertensive effect when combined with sympathomimetics
it increases the toxicity of serotonergic agents
It may enhance the effects when combined with triamcinolone by immunosuppressive effects
ozanimod: they may increase the bradycardic effect of Bradycardia-Causing Agents
ozanimod: they may increase the bradycardic effect of Bradycardia-Causing Agents
ozanimod: they may increase the bradycardic effect of Bradycardia-Causing Agents
ozanimod: they may increase the bradycardic effect of Bradycardia-Causing Agents
ozanimod: they may increase the bradycardic effect of Bradycardia-Causing Agents
ozanimod: they may increase the CNS depressant effect of CNS Depressants
ozanimod: they may increase the CNS depressant effect of CNS Depressants
ozanimod: they may increase the CNS depressant effect of CNS Depressants
ozanimod: they may increase the CNS depressant effect of CNS Depressants
ozanimod: they may increase the CNS depressant effect of CNS Depressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with corticosteroids
may have an increased immunosuppressive effect when combined with corticosteroids
may have an increased immunosuppressive effect when combined with corticosteroids
may have an increased immunosuppressive effect when combined with corticosteroids
may have an increased immunosuppressive effect when combined with corticosteroids
ozanimod: it may decrease the therapeutic effect of myelosuppressive agents
ozanimod: it may decrease the therapeutic effect of myelosuppressive agents
ozanimod: it may decrease the therapeutic effect of myelosuppressive agents
ozanimod: it may decrease the therapeutic effect of myelosuppressive agents
ozanimod: it may decrease the therapeutic effect of myelosuppressive agents
ozanimod: it may enhance the bradycardic effect of Bradycardia-Causing Agents
risk of severe infection due to immunosuppressive effects
when both drugs are combined, there may be an increase in qtc interval  
osimertinib and ozanimod, when used simultaneously, increase the QTc interval
May increase the tachycardic effect (hypertension)
it increases the toxicity of serotonergic agents
it increases the toxicity of serotonergic agents
it increases the toxicity of serotonergic agents
it increases the toxicity of serotonergic agents
it increases the toxicity of serotonergic agents
it increases the toxicity of serotonergic agents
may increase the hypertension effect of sympathomimetic drugs
may increase the hypertension effect of sympathomimetic drugs
may increase the bradycardic effect of bradycardia causing agents
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may have an increased immunosuppressive effect when combined with immunosuppressants
may decrease the therapeutic effect when combined with gastrointestinal agents
may decrease the therapeutic effect when combined with gastrointestinal agents
may decrease the therapeutic effect when combined with gastrointestinal agents
may decrease the therapeutic effect when combined with gastrointestinal agents
may decrease the therapeutic effect when combined with gastrointestinal agents
Actions and Spectrum:
It is used for the treatment of relapsing forms of multiple sclerosis (MS). Here’s some information about the actions and spectrum of ozanimod:
>10%:Â
Upper respiratory tract infectionÂ
<1%:Â
BradycardiaÂ
Macular edemaÂ
Ozanimod is contraindicated in patients hypersensitive to the active ingredient.Â
Pregnancy consideration:Â Â
No data is available regarding any fetal defects caused due to drug intake during pregnancy.Â
Breastfeeding warnings:Â Â
No data is available regarding the excretion of the drug in breast milk.Â
Pregnancy category:Â
Patient information leaflet:
Generic Name: ozanimod
Why do we use ozanimod?Â
ozanimod is used primarily for the treatment of relapsing forms of multiple sclerosis (MS). Here are some reasons why ozanimod may be prescribed.
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