Microplastics and Misinformation: What Science Really Says
November 12, 2025
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Brand Name :
Rimactane, rifadin, rifadin IV
Synonyms :
Rifampicin, Rifampicine
Class :
Anti-tubercular agents
Brand Name :
Rimactane, rifadin, rifadin IV
Synonyms :
Rifampicin, Rifampicine
Class :
Anti-tubercular agents
Dosage Forms & StrengthsÂ
CapsuleÂ
150mgÂ
300mgÂ
10mg/kg orally twice a week. Do not exceed 600mg/day
600mg every 12 hours for two days
600mg/day orally for four days
Dosage Forms & StrengthsÂ
CapsuleÂ
150mgÂ
300mgÂ
10-20mg/kg orally twice a week. Do not exceed 600mg/day
<1 month:10mg/kg orally every 12 hours for two days
>1 month: 20mg/kg orally every 12 hours for two days
<1 month:10mg/kg orally every 12 hours for two days
>1 month: 20mg/kg orally every 12 hours for two days
<1 month:10mg/kg orally for four days
>1 month: 20mg/kg orally for four days
Refer adult dosingÂ
may diminish the serum concentration
may diminish the serum concentration
may diminish the serum concentration
may diminish the serum concentration
may diminish the serum concentration
may diminish the serum concentration when combined with fenfluramine
rifampin: they may enhance the serum concentration of atorvastatin
rifampin: they may diminish the serum concentration of avatrombopag
rifampin: they may diminish the serum concentration of caspofungin
rifampin: they may diminish the serum concentration of deferasirox
rifampinin: they may diminish the serum concentration of dolutegravir
rifampin: they may diminish the serum concentration of fluconazole
may diminish the concentration of serum when combined with selexipag
It may diminish the effect when combined with irinotecan liposomal by affecting CYP2B6 metabolism
rifampin: they may diminish the serum concentration of canagliflozin
it decreases by affecting the hepatic enzyme CYP3A4 metabolism
may diminish the serum concentration when combined with caspofungin
may increase the toxic effect of cefazolin
May decrease the diagnostic effect when combined with tuberculin Tests
may diminish the serum concentration of each other when combined
levels of norethisterone will be lowered due to increased metabolism rate when taken with rifampin
it decreases the concentration of rilpivirine in the serum
rifampin: they may diminish the serum concentration of atazanavir
rifampin: they may diminish the serum concentration of cobicistat
rifampin: they may diminish the serum concentration of delavirdine
It may diminish the effect when combined with lumateperone by affecting CYP3A4 metabolism
rifampin decreases the effect of fedratinib by altering the intestinal/hepatic CYP3A4 enzyme metabolism
rifampin decreases the effect/level of gilteritinib
it may increase the toxicity of each other
it may increase the toxicity of each other
may decrease the absorption of activated charcoal
may enhance the serum concentration of elbasvir/grazoprevir
it increases the effect of CNS depressants
may increase the hepatotoxic effect
may diminish the serum concentration
may enhance the adverse/toxic effect of rifampin
may enhance the adverse/toxic effect of rifampin
may enhance the adverse/toxic effect of rifampin
may enhance the adverse/toxic effect of rifampin
may enhance the adverse/toxic effect of rifampin
rifampin: they may diminish the serum concentration of fexofenadine
rifampin: they may enhance serum concentrations of the active metabolites of leflunomide
it decreases the concentration of thyroid products in serum
it decreases the concentration of thyroid products in serum
it decreases the concentration of thyroid products in serum
it decreases the concentration of thyroid products in serum
It may enhance toxicity when combined with cholic acid by diminishing the elimination
rifampin: they may diminish the serum concentration of trimethoprim
may decrease the level of serum concentration
the effect of action increases by effecting enzyme CYP2B6 metabolism
is having an antagonistic impact over brentuximab vedotin by showing altered intestinal/hepatic CYP3A4 enzyme metabolism.
when both drugs are combined, there may be an increased metabolism of erlotinib  
increase the therapeutic effect of daunorubicin by P-glycoprotein efflux transporter
increases serum level of cabazitaxel by affecting the enzyme CYP3A4
rifampin decreases the effect of gefitinib by altering the intestinal/ hepatic CYP3A4 enzyme metabolism
increase the therapeutic effect of idarubicin by P-glycoprotein efflux transporter
it decreases by affecting the hepatic enzyme CYP2C9 metabolism
may decrease the level by affecting the hepatic enzyme CYP3A4 metabolism
may decrease the level by affecting the hepatic enzyme CYP3A4 metabolism
metronidazole/tetracycline/bismuth subsalicylateÂ
by altering the intestinal/hepatic CYP3A4 metabolism, the effects of rifampin will be decreased by tetracycline
Frequency defined:Â Â
1-10%Â
RashÂ
AnorexiaÂ
VomitingÂ
CrampsÂ
PancreatitisÂ
Epigastric diseaseÂ
NauseaÂ
DiarrheaÂ
Pseudomembranous colitisÂ
Frequency not defined:Â Â
EdemaÂ
AtaxiaÂ
Fever Â
HeadacheÂ
Behavioral changesÂ
Muscular weaknessÂ
FlushingÂ
Impaired concentrationÂ
FatigueÂ
NumbnessÂ
DizzinessÂ
Post-marketing reportsÂ
HepatitisÂ
Eosinophilic pneumoniaÂ
Respiratory failureÂ
PneumonitisÂ
Pregnancy consideration: Insufficient data availableÂ
Lactation: Excretion of the drug in human breast milk is unknownÂ
Pregnancy category:Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.  Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this categoryÂ
Patient information leafletÂ
Generic Name: rifampinÂ
Pronounced: [ rif-AM-pin ]Â
Why do we use rifampin?Â
Rifampin is an antibiotic that is used to treat a variety of bacterial infections. It belongs to a class of antibiotics called rifamycins. Rifampin is used to treat respiratory tract infections, including tuberculosis and pneumonia. It can also be used to treat infections of the skin and soft tissues and to prevent infections in people who are at high risk of contracting a bacterial infection, such as those with compromised immune systems or those who have had surgeryÂ
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