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November 25, 2025
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Brand Name :
Keveyis
(United States) [Available] ,Ormalvi
(United States) [Available]Synonyms :
dichlorphenamide
Class :
Diuretics and Carbonic Anhydrase Inhibitors
Brand Name :
Keveyis
(United States) [Available] ,Ormalvi
(United States) [Available]Synonyms :
dichlorphenamide
Class :
Diuretics and Carbonic Anhydrase Inhibitors
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may diminish the excretion when combined with lithium
may diminish the excretion when combined with lithium
choline magnesium trisalicylate
Salicylates may enhance the risk of adverse effects of Carbonic Anhydrase Inhibitors
choline magnesium trisalicylate
may have an increasingly adverse effect when combined with carbonic anhydrase inhibitors
May enhance the toxic effects of the other by pharmacodynamic synergism
levels of aspirin may be increased when combined with dichlorphenamide
may decrease the absorption when combined with thiazide diuretics
metronidazole/tetracycline/bismuth subsalicylateÂ
levels of bismuth subsalicylate can be increased due to dichlorphenamide
may increase the sensitivity to pressor effects
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may enhance the rate of excretion resulting in the lower serum level
may enhance the rate of excretion resulting in the lower serum level
may enhance the rate of excretion resulting in the lower serum level
may enhance the rate of excretion resulting in the lower serum level
may enhance the rate of excretion resulting in the lower serum level
carbonic Anhydrase Inhibitors may reduce the rate of excretion of amphetamines
carbonic Anhydrase Inhibitors may reduce the rate of excretion of amphetamines
carbonic Anhydrase Inhibitors may reduce the rate of excretion of amphetamines
antifungal drugs may increase the hypokalemic effect of dichlorphenamide
antifungal drugs may increase the hypokalemic effect of dichlorphenamide
antifungal drugs may increase the hypokalemic effect of dichlorphenamide
antifungal drugs may increase the hypokalemic effect of dichlorphenamide
antifungal drugs may increase the hypokalemic effect of dichlorphenamide
Laxatives may increase the hypokalemic effect of dichlorphenamide
Laxatives may increase the hypokalemic effect of dichlorphenamide
Laxatives may increase the hypokalemic effect of dichlorphenamide
sodium picosulfate, citric acid, and magnesium oxide
Laxatives may increase the hypokalemic effect of dichlorphenamide
Laxatives may increase the hypokalemic effect of dichlorphenamide
loop Diuretics may increase the hypokalemic effect of dichlorphenamide
loop Diuretics may increase the hypokalemic effect of dichlorphenamide
loop Diuretics may increase the hypokalemic effect of dichlorphenamide
penicillins may enhance the hypokalemic effect of dichlorphenamide
penicillins may enhance the hypokalemic effect of dichlorphenamide
penicillins may enhance the hypokalemic effect of dichlorphenamide
penicillins may enhance the hypokalemic effect of dichlorphenamide
penicillins may enhance the hypokalemic effect of dichlorphenamide
Thiazides may increase the hypokalemic effect of Dichlorphenamide
Thiazides may increase the hypokalemic effect of Dichlorphenamide
Thiazides may increase the hypokalemic effect of Dichlorphenamide
Thiazides may increase the hypokalemic effect of Dichlorphenamide
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may enhance the serum concentration when combined with alpha-/beta-agonists
It may increase the hypokalemic effect when combined with laxatives
It may increase the hypokalemic effect when combined with laxatives
It may increase the hypokalemic effect when combined with laxatives
It may increase the hypokalemic effect when combined with laxatives
sodium picosulfate, citric acid, and magnesium oxide
It may increase the hypokalemic effect when combined with laxatives
dichlorphenamide: they may increase the hypokalemic effect of penicillins
amoxicillin and clavulanate potassium
dichlorphenamide: they may increase the hypokalemic effect of penicillins
dichlorphenamide: they may increase the hypokalemic effect of penicillins
dichlorphenamide: they may increase the hypokalemic effect of penicillins
dichlorphenamide: they may increase the hypokalemic effect of penicillins
dichlorphenamide: they may increase the hypokalemic effect when combined with thiazides
dichlorphenamide: they may increase the hypokalemic effect when combined with thiazides
dichlorphenamide: they may increase the hypokalemic effect when combined with thiazides
dichlorphenamide: they may increase the hypokalemic effect when combined with thiazides
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
acetaminophen/dextromethorphan/pseudoephedrine/guaifenesin
it may enhance the risk of nephrotoxicity when combined with Diuretics
brompheniramine, dextromethorphan and phenylephrine
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
dichlorphenamide : it may increase the toxic effect of Methemoglobinemia Associated Agents
dichlorphenamide : it may increase the toxic effect of Methemoglobinemia Associated Agents
dichlorphenamide : it may increase the toxic effect of Methemoglobinemia Associated Agents
dichlorphenamide : it may increase the toxic effect of Methemoglobinemia Associated Agents
dichlorphenamide : it may increase the toxic effect of Methemoglobinemia Associated Agents
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may increase the adverse/toxic effect of diuretics
may increase the adverse/toxic effect of diuretics
may increase the adverse/toxic effect of diuretics
may increase the adverse/toxic effect of diuretics
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may have an increased hypercalcemic effect when combined with vitamin D analogs
it may increase the level of serum concentration of memantine 
it may decrease the rate of excretion of amphetamines 
it may increase the level of serum concentration of memantine
carbonic Anhydrase Inhibitors may increase the levels of serum concentration of amantadine
carbonic Anhydrase Inhibitors may decrease the levels of serum concentration of lithium
carbonic Anhydrase Inhibitors may increase the risk of adverse effects of metformin
Carbonic Anhydrase Inhibitors may increase the levels of serum concentration of Alpha-/Beta-Agonists
may decrease serum potassium levels
carbonic anhydrase inhibitors may enhance the levels of serum concentration of alpha-/beta-agonists
may decrease the serum concentration of each other
they increase the toxicity of metformin
may enhance the serum concentration of BRCP/ABCG2 inhibitors
choline magnesium trisalicylate
may enhance the adverse effect of carbonic anhydrase inhibitors
may diminish the excretion of amphetamines
may enhance the serum concentration of amantadine
may have an increased hypokalemic effect when combined with dichlorphenamide
may increase the levels of serum concentration
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the adverse/toxic effect of Opioid Agonists
buprenorphine,long-acting injectionÂ
may increase the adverse/toxic effect of Opioid Agonists
polyethylene glycol and electrolytesÂ
They may increase the nephrotoxic effect when combined with polyethylene Glycol-electrolyte Solution
may increase the hypoglycemic effect of Antidiabetic Agents
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
diacerein: they may increase the therapeutic effect when combined with diuretics
they increase the toxicity of saxagliptin/metformin
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
acetaminophen/dextromethorphan/pseudoephedrine/guaifenesin
It may enhance the risk of bleeding when combined with Decongestants
brompheniramine, dextromethorphan and phenylephrine
It may enhance the risk of bleeding when combined with Decongestants
It may enhance the risk of bleeding when combined with Decongestants
it increases the effect of hypokalemia of thiazide and other diuretics
mu-opioid receptor agonists: they may increase the toxic effect of diuretics
mu-opioid receptor agonists: they may increase the toxic effect of diuretics
the levels of serum potassium may be decreased when dichlorphenamide is taken with cyanocobalamin
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may have an increased orthostatic hypotensive effect when combined with thiazide diuretics
Adverse drug reactions:  Â
Frequency Defined Â
>10% Â
Dysgeusia Â
Confusional state Â
Paresthesia Â
Cognitive disorder Â
1-10% Â
Dizziness  Â
Diarrhea Â
Nausea Â
Malaise Â
Headache Â
Hypoesthesia  Â
Lethargy Â
Fatigue Â
Muscle spasms  Â
Rash Â
 Â
 Â
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Pregnancy warnings:    Â
Pregnancy category: N/AÂ
Breastfeeding warnings: Â
Pregnancy Categories:      Â
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first trimester or the later trimester.      Â
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women      Â
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women      Â
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits      Â
Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.      Â
Category N: There is no data available for the drug under this category
Patient Information Leaflet Â
Generic Name: dichlorphenamideÂ
Pronounced: DYE-klor-FEN-a-mideÂ
Why do we use dichlorphenamide?Â
dichlorphenamide is a diuretic drug that belongs to the subclass carbonic anhydrase used to treat attacks of muscle weakness or loss of muscle movementÂ
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