Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
N/A
Synonyms :
magnesium trisilicate
Class :
Antacid and alkalizer
Brand Name :
N/A
Synonyms :
magnesium trisilicate
Class :
Antacid and alkalizer
Dosage Forms & StrengthsÂ
Tablet Â
120 mg Â
300 mgÂ
SuspensionÂ
50mg/ml Â
Take one to four tablets orally daily as required
Not determined Â
Refer to adult dosingÂ
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
antacids may reduce the absorption of quinolones
antacids may reduce the absorption of quinolones
bismuth subcitrate, metronidazole and tetracycline
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
it may reduce the therapeutic effect of bisacodyl
may reduce the level of serum concentration of acalabrutinib
may diminish the bioavailability of corticosteroids
may diminish the serum concentration
may diminish the quinolones absorption
may diminish the absorption of iron preparations
may diminish the therapeutic effect when combined with lanthanum
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may diminish the serum concentration when combined with fosinopril
may diminish the serum concentration when combined
may diminish the absorption when combined with quinolones
may diminish the absorption when combined with quinolones
atazanavir: they may diminish the absorption of antacids
belumosudil: they may diminish the serum concentration of antacids
bisacodyl: they may decrease the therapeutic effect of antacids
bismuth subnitrate: they may decrease the therapeutic effect of antacids
bosutinib: they may diminish the serum concentration of antacids
cefuroxime: they may diminish the serum concentration of antacids
chloroquine: they may diminish the serum concentration of antacids
antacids: they may diminish the serum concentration of dabigatran
antacids: they may diminish the serum concentration of dasatinib
delavirdine: they may diminish the serum concentration of antacids
itraconazole: they may diminish the serum concentration of antacids
ketoconazole: they may diminish the serum concentration of antacids
ledipasvir: they may diminish the serum concentration of antacids
levoketoconazole: they may diminish the absorption of antacids
mesalamine: they may decrease the therapeutic effect of antacids
methenamine: they may decrease the therapeutic effect of antacids
neratinib: they may diminish the serum concentration of antacids
pexidartinib: they may diminish the serum concentration of antacids
potassium phosphate: they may diminish the serum concentration of antacids
sotorasib: they may diminish the serum concentration of antacids
sparsentan: they may diminish the serum concentration of antacids
sulpiride: they may diminish the serum concentration of antacids
velpatasvir: they may diminish the serum concentration of antacids
ciprofloxacin inhaled (Pending FDA approval)Â
may diminish the absorption of Quinolones
Alpha-Lipoic Acid: they may diminish the absorption of antacids
bisacodyl rectal: they may decrease the therapeutic effect of antacids
bismuth subgallate: they may decrease the therapeutic effect of antacids
cabotegravir: they may diminish the absorption of antacids
elvitegravir: they may diminish the serum concentration of antacids
erlotinib: they may diminish the serum concentration of antacids
erdafitinib: they may diminish the serum concentration of antacids
gefitinib: they may diminish the serum concentration of antacids
hyoscyamine: they may diminish the serum concentration of antacids
nilotinib: they may diminish the serum concentration of antacids
phosphate binders: they may diminish the serum concentration of antacids
phosphate binders: they may diminish the serum concentration of antacids
phosphate binders: they may diminish the serum concentration of antacids
tetraferric tricitrate decahydrate
phosphate binders: they may diminish the serum concentration of antacids
phosphate binders: they may diminish the serum concentration of antacids
riociguat: they may diminish the serum concentration of antacids
selpercatinib: they may diminish the serum concentration of antacids
may decrease the therapeutic effect of each other when combined
The absorption of nitrofurantoin may be reduced by magnesium trisilicate
antacids decrease the concentration of cefditoren in serum
antacids decrease the systemic absorption of naproxen
they decrease the absorption of naproxen
antacids can reduce the amount of cefditoren present in the bloodstream
levonorgestrel: they may diminish the serum concentration of antacids
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
antacids may decrease the absorption of quinolones
antacids may decrease the absorption of quinolones
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
antacids may reduce the serum concentration of multivitamins
antacids may reduce the serum concentration of minerals
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
antacids: they may decrease the therapeutic effect of laxative
antacids: they may decrease the therapeutic effect of laxative
antacids: they may decrease the therapeutic effect of laxative
antacids: they may decrease the therapeutic effect of laxative
sodium picosulfate, citric acid, and magnesium oxide
antacids: they may decrease the therapeutic effect of laxative
may enhance the absorption of each other when combined
may enhance the absorption of each other when combined
it may decrease the excretion of amphetamines 
antacids reduce the systemic absorption of bromeperidol
antacids reduce the concentration of captopril in serum
antacids reduces the systemic absorption of diacerein
antacids reduce the concentration of octreotide in the serum
antacids reduce the excretion of quinidine
antacids reduce the concentration of rosuvastatin in the serum
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
bromeperidol: they may decrease the absorption of antacids:
cefpodoxime: they may diminish the serum concentration of antacids
rosuvastatin: they may diminish the serum concentration of antacids
antacids can lower the levels of captopril in the bloodstream
antacids can reduce the absorption of diacerein
calcium polystyrene sulfonateÂ
calcium polystyrene sulfonate: they may increase the toxic effect of antacids
isoniazid: they may diminish the absorption of antacids
octreotide: they may diminish the serum concentration of antacids
dried ferrous sulfate/folic acidÂ
reduces the gastrointestinal absorption of iron
magnesium trisilicate can cause a decrease in the absorption of ferrous bisglycinate, leading to reduced serum concentration and potentially compromising efficacy
they decrease the concentration of active metabolites of infigratinib in the serum
Actions and SpectrumÂ
Magnesium trisilicate acts as an antacid by neutralizing extra stomach acid. It does so through a chemical reaction in which the magnesium trisilicate reacts with the hydrochloric acid in the stomach, forming magnesium chloride and silicon dioxide.
Frequency not defined Â
RashÂ
Stomach upsetÂ
NauseaÂ
Acute toxicityÂ
Black Box WarningÂ
None
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
Magnesium trisilicate has adsorbent properties. It can bind to bile salts and other substances, contributing to its overall effectiveness in reducing symptoms associated with gastric acidity.Â
PharmacodynamicsÂ
Unabsorbed magnesium in the intestines can exert an osmotic effect, drawing water into the intestines and potentially causing diarrhea.Â
High doses of magnesium trisilicate may lead to a laxative effect due to the presence of unabsorbed magnesium in the gastrointestinal tract.Â
PharmacokineticsÂ
Absorption  Â
Magnesium trisilicate is absorbed primarily in the gastrointestinal tract.Â
DistributionÂ
Magnesium trisilicate is distributed throughout the body. Â
MetabolismÂ
Magnesium trisilicate does not undergo significant metabolic transformations within the body.Â
Elimination and excretionÂ
Magnesium trisilicate is excreted through the feces.Â
AdministrationÂ
Magnesium trisilicate is available in various forms including tablets, chewable tablets, and suspensions.Â
Patient information leafletÂ
Generic Name: magnesium trisilicateÂ
Why do we use magnesium trisilicate?Â
Magnesium trisilicate is used as an antacid to provide symptomatic relief from conditions such as indigestion and heartburn.  Â
Magnesium trisilicate is used in the management of peptic ulcers to relieve symptoms associated with excess gastric acidity.Â
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