The Navigation Model of Therapy: Why Awareness Changes Everything
November 16, 2025
Brand Name :
Synonyms :
Class :
Oral
Initial dose: Administer 50mg orally thrice a day
Maintenance dose: Administer 100 to 400mg/day orally in divided doses.
Intramuscular
Initial dose: Administer 25mg intramuscularly.
Can be given in 30 to 60 minutes.
Maintenance dose: Administer 25 to 200mg/day
may decrease the therapeutic effect when combined with anti-parkinson agents
may decrease the therapeutic effect when combined with anti-parkinson agents
may decrease the therapeutic effect when combined with anti-parkinson agents
may decrease the therapeutic effect when combined with anti-parkinson agents
may decrease the therapeutic effect when combined with anti-parkinson agents
anti-Parkinson Agents may diminish the therapeutic effect of anti-psychotic Agents
anti-Parkinson Agents may diminish the therapeutic effect of anti-psychotic Agents
anti-Parkinson Agents may diminish the therapeutic effect of anti-psychotic Agents
anti-Parkinson Agents may diminish the therapeutic effect of anti-psychotic Agents
anti-Parkinson Agents may diminish the therapeutic effect of anti-psychotic Agents
may decrease the therapeutic effect when combined with antipsychotic agents
may decrease the therapeutic effect when combined with antipsychotic agents
may decrease the therapeutic effect when combined with antipsychotic agents
may decrease the therapeutic effect when combined with antipsychotic agents
may decrease the therapeutic effect when combined with antipsychotic agents
when both drugs are combined, there may be an increased risk or severity of QTC prolongation  
it decreases the effects of antipsychotic agents
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
may enhance the hypotensive effect of beta-blockers
may enhance the hypotensive effect of beta-blockers
may enhance the hypotensive effect of beta-blockers
may enhance the hypotensive effect of beta-blockers
may enhance the hypotensive effect of beta-blockers
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may diminish the therapeutic effect of the drug
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
It may increase the neurotoxic effect of Antipsychotic Agents
seizure lowering agents increase the toxic or adverse effects of other antipsychotic agents
serotonergic Agents may enhance the adverse/toxic effect of antipsychotic Agents
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
may enhance the adverse effect of antipsychotic agents
may enhance the adverse effect of antipsychotic agents
may enhance the adverse effect of antipsychotic agents
may enhance the adverse effect of antipsychotic agents
may enhance the adverse effect of antipsychotic agents
may enhance the neurotoxic effect of antipsychotic agents
may enhance the neurotoxic effect of antipsychotic agents
may enhance the neurotoxic effect of antipsychotic agents
may enhance the neurotoxic effect of antipsychotic agents
may enhance the neurotoxic effect of antipsychotic agents
moexipril/hydrochlorothiazideÂ
may increase the hypotensive effect of blood pressure-lowering agents
may enhance the bradycardic effect of beta blockers
may increase the hypotensive effect of blood pressure-lowering agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
It could potentially amplify the QTc-prolonging effect of antipsychotic medications known for their QT-prolongation effects
It may enhance the serum concentration when combined with CYP3A4 Substrates
It may enhance the serum concentration when combined with CYP3A4 Substrates
It may enhance the serum concentration when combined with CYP3A4 Substrates
It may enhance the serum concentration when combined with CYP3A4 Substrates
It may enhance the serum concentration when combined with CYP3A4 Substrates
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased neurotoxic effect when combined with antipsychotic agents
may have an increased neurotoxic effect when combined with antipsychotic agents
itopride: they may decrease the therapeutic effect of antipsychotics
nicorandil: they may decrease the therapeutic effect of antipsychotics
quinagolide: they may decrease the therapeutic effect of antipsychotics
ramosetron: they may decrease the therapeutic effect of antipsychotics
When mesoridazine is used together in combination with profenamine, this leads to reduction in therapeutic effectiveness of profenamine
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
antipsychotic agents increase the arrhythmogenic effect of mequitazine in the serum