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Brand Name :
Lanoxin
Synonyms :
Class :
Antidysrhythmics
Brand Name :
Lanoxin
Synonyms :
Class :
Antidysrhythmics
Dosage Forms & Strengths
Solution
0.05mg/mL
Injectable solution
0.1mg/mL
0.25mg/mL
Tablet
0.0625mg
0.125mg
0.1875mg
0.25mg
Dosage Forms & Strengths
Solution
0.05mg/mL
Injectable solution
0.1mg/mL
0.25mg/mL
Tablet
0.0625mg
0.125mg
0.1875mg
0.25mg
digoxin: they may enhance the serum concentration of glycoprotein IIa Inhibitors
Increased level or effect of digoxin by affecting intestinal flora.
Sucralfate may diminish the serum concentration of digoxin
may increase the immunosuppressive effect
may enhance the serum concentration of P-glycoprotein/ABCB1 inhibitors
may enhance the serum concentrations of flibanserin
may enhance the serum concentration of P-glycoprotein/ABCB1 Inhibitors
serum concentration of cardiac glycosides is increased by amiodarone
side effects of cardiac glycosides are increased by bretylium
anthracyclines may decrease the serum concentration of digoxin
anthracyclines may decrease the serum concentration of digoxin
thyroid products decrease the concentration of cardiac glycosides in serum
thyroid products decrease the concentration of cardiac glycosides in serum
thyroid products decrease the concentration of cardiac glycosides in serum
thyroid products decrease the concentration of cardiac glycosides in serum
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may enhance the serum concentration when combined with digoxin
may enhance the serum concentration when combined with digoxin
may enhance the serum concentration when combined with digoxin
may enhance the serum concentration when combined with digoxin
may enhance the serum concentration when combined with digoxin
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
It may enhance the effects when combined with pleurisy root by pharmacodynamic synergism
It may enhance effects when combined with inamrinone by pharmacodynamic synergism
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may decrease the levels of serum concentration of Cardiac Glycosides
may decrease the levels of serum concentration of Cardiac Glycosides
may decrease the levels of serum concentration of Cardiac Glycosides
may decrease the levels of serum concentration of Cardiac Glycosides
calcium salts have the potential to intensify the arrhythmogenic effect of cardiac glycosides
calcium salts have the potential to intensify the arrhythmogenic effect of cardiac glycosides
calcium salts have the potential to intensify the arrhythmogenic effect of cardiac glycosides
calcium salts have the potential to intensify the arrhythmogenic effect of cardiac glycosides
calcium salts have the potential to intensify the arrhythmogenic effect of cardiac glycosides
It may enhance the toxicity when combined with vitamin D
When mometasone furoate is used together with digoxin, this leads to enhanced risk or seriousness of adverse outcomes
When ponesimod is used together with digoxin, this leads to enhanced risk or seriousness of bradycardia
may diminish the serum concentration of 5-Aminosalicylic Acid Derivatives
may diminish the serum concentration of 5-Aminosalicylic Acid Derivatives
When digoxin is used together with givinostat, this leads to enhanced risk or seriousness of Qtc prolongation
When digoxin is used together with oleandomycin, this leads to enhanced concentration serum of digoxin
When digoxin is used together with ridaforolimus, this leads to enhanced concentration serum of digoxin
may increase the adverse/toxic effect of cardiac glycosides
may increase the adverse/toxic effect of cardiac glycosides
may increase the adverse/toxic effect of cardiac glycosides
When digoxin is used together with halometasone, this leads to enhanced risk or seriousness of adverse outcomes
nafcillin will increase the levels of digoxin by altering the intestinal flora.
when both drugs combine melphalan decreases the activity of digoxin.
the effect of action of digoxin decreases by inhibiting GI absorption.
when both the drugs are combined, carmustine may decrease the renal secretion of digoxin and increases the serum level
when both drugs are combined, there may be an increased effect of digoxin by altering intestinal flora
vandetanib may enhance the serum concentration of digoxin
demeclocycline may interfere with the intestinal flora and reduce the effects of digoxin
doxycycline may interfere with the intestinal flora and reduce the effects of digoxin
encorafenib increases the level of digoxin in the body
when both drugs are combined, there may be an increase in the serum concentration of digoxin
sitagliptin increases the concentration of digoxin
linagliptin increases the concentration of digoxin
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may decrease the absorption of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
it enhances the serum potassium levels
may enhance the arrhythmogenic effect of cardiac glycosides
may decrease the absorption of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may increase the serum concentration of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may enhance the AV-blocking effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the levels of serum concentration of cardiac glycosides
may increase the levels of serum concentration of cardiac glycosides
may increase the levels of serum concentration of cardiac glycosides
may increase the levels of serum concentration of cardiac glycosides
may increase the levels of serum concentration of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may increase the level of effectiveness through P-glycoprotein MDR1 efflux transporter
may increase the toxicity of each other
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may enhance the arrhythmogenic effect of cardiac glycosides
may increase the bradycardiac effect
may enhance the adverse/toxic effect of cardiac glycosides
may enhance the adverse/toxic effect of cardiac glycosides
may enhance the adverse/toxic effect of cardiac glycosides
may enhance the adverse/toxic effect of cardiac glycosides
may increase the risk of adverse effect of cardiac glycosides
may increase the risk of adverse effect of cardiac glycosides
may increase the risk of adverse effect of cardiac glycosides
may enhance the serum concentration of telmisartan
may increase the arrhythmogenic effect of Vitamin D analogs
may increase the toxic effect of thiazide and thiazide like diuretics
lisinopril/hydrochlorothiazide
may increase the toxic effect of thiazide and thiazide like diuretics
may enhance the serum concentration when combined with digoxin
may enhance the serum concentration when combined with digoxin
may increase the risk of adverse effect of cardiac glycosides
may have an increased adverse effect when combined with cardiac glycosides
may increase the adverse effect of Amphotericin B
tramadol: they may enhance the serum concentration of digoxin
may enhance the concentration of serum when combined with digoxin
may increase the toxic effect when combined
5-Aminosalicylic Acid Derivatives: they may diminish the serum concentration of cardiac glycosides
5-Aminosalicylic Acid Derivatives: they may diminish the serum concentration of cardiac glycosides
may increase the AV-blocking effect when combined
sitagliptin: they may enhance the serum concentration of digoxin
trimethoprim: they may enhance the serum concentration of digoxin
may enhance the serum concentration of each other when combined
may diminish the concentration of serum when combined with cardiac glycosides
neomycin/polymyxin B/bacitracin topical
may diminish the concentration of serum when combined with cardiac glycosides
may diminish the concentration of serum when combined with cardiac glycosides
may diminish the concentration of serum when combined with cardiac glycosides
may diminish the concentration of serum when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
It may enhance the risk of adverse effects when combined with cardiac glycosides
It may enhance the risk of adverse effects when combined with cardiac glycosides
It may enhance the risk of adverse effects when combined with cardiac glycosides
It may enhance the risk of adverse effects when combined with cardiac glycosides
It may enhance the risk of adverse effects when combined with cardiac glycosides
may have an increased arrhythmogenic effect when combined with cardiac glycosides
canagliflozin: they may enhance the serum concentration of digoxin
calcium salts enhance the arrhythmogenic effects of cardiac glycosides
calcium salts enhance the arrhythmogenic effects of cardiac glycosides
calcium salts enhance the arrhythmogenic effects of cardiac glycosides
calcium salts enhance the arrhythmogenic effects of cardiac glycosides
macrolide antibiotics increase cardiac glycoside serum concentration
digoxin when administered with amiloride can increase the serum levels of potassium
may have an increased adverse effect when combined with cardiac glycosides
may have an increased adverse effect when combined with cardiac glycosides
the rate of excretion of digoxin may be reduced
synergistic effects may occur
ispaghula husk may lower or decrease the rate of GI absorption of cardiac glycosides
The therapeutic activity of digoxin may reduce due to poor absorption led by stomatitis.
levels of digoxin are increased by meclizine through an unspecific mechanism
Adverse drug reactions
Frequency defined
1-10%
Diarrhea (3.2%)
Vomiting (1.6%)
Maculopapular rash (1.6%)
Dizziness (4.9%)
Mental disturbances (4.1%)
Headache (3.2%)
Nausea (3.2%)
<1%
Anorexia
Arrhythmia
Cardiac dysrhythmia
Frequency Not Defined
Asystole
Heart block
Tachycardia
Visual disturbance
Pregnancy warnings:
US FDA pregnancy category: N/A
Lactation:
Excreted into human milk is Unknown
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: digoxin
Why do we use digoxin?
digoxin IS an Antidysrhythmics used for Heart Failure/Atrial Fibrillation
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