A Game-Changer for Diabetes: Polymer Delivers Insulin Painlessly Through Skin
November 25, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Riopan, Maoson, Losospan, Ron Acid, Lowsium, Ri-Mag
Synonyms :
magaldrate
Class :
Antacids
Brand Name :
Riopan, Maoson, Losospan, Ron Acid, Lowsium, Ri-Mag
Synonyms :
magaldrate
Class :
Antacids
Dosage Forms & StrengthsÂ
Oral suspensionÂ
540mg/5mlÂ
After meals and before bed, administer 5 to 10ml (1 to 2 tablespoons). Do not exceed 80ml.
Safety and efficacy not established.Â
Refer adult dosingÂ
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
antacids May decrease the bioavailability of corticosteroids
bismuth subcitrate, metronidazole and tetracycline
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids may decrease the absorption of tetracyclines
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the bioavailability of corticosteroids
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
antacids: they may diminish the serum concentration of calcium salts
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with phosphate supplements
may diminish the absorption when combined with quinolones
may diminish the absorption when combined with quinolones
may diminish the effect of each other when combined
may diminish the effect of each other when combined
may diminish the effect of each other when combined
may diminish the effect of each other when combined
may diminish the effect of each other when combined
it may reduce the therapeutic effect of bisacodyl
may reduce the level of serum concentration of acalabrutinib
may diminish the bioavailability of corticosteroids
may diminish the serum concentration
may diminish the quinolones absorption
may diminish the absorption of iron preparations
may diminish the bioavailability of corticosteroids
may diminish the absorption of quinolones
may diminish the therapeutic effect when combined with lanthanum
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may reduce the rate of bioavailability of corticosteroids
may diminish the serum concentration when combined with fosinopril
may diminish the serum concentration when combined
may diminish the absorption when combined with quinolones
may diminish the absorption when combined with quinolones
atazanavir: they may diminish the absorption of antacids
belumosudil: they may diminish the serum concentration of antacids
bisacodyl: they may decrease the therapeutic effect of antacids
bismuth subnitrate: they may decrease the therapeutic effect of antacids
bosutinib: they may diminish the serum concentration of antacids
cefuroxime: they may diminish the serum concentration of antacids
chloroquine: they may diminish the serum concentration of antacids
antacids: they may diminish the serum concentration of dabigatran
antacids: they may diminish the serum concentration of dasatinib
delavirdine: they may diminish the serum concentration of antacids
erlotinib: they may diminish the serum concentration of antacids
gefitinib: they may diminish the serum concentration of antacids
hyoscyamine: they may diminish the serum concentration of antacids
itraconazole: they may diminish the serum concentration of antacids
ketoconazole: they may diminish the serum concentration of antacids
ledipasvir: they may diminish the serum concentration of antacids
levoketoconazole: they may diminish the absorption of antacids
mesalamine: they may decrease the therapeutic effect of antacids
methenamine: they may decrease the therapeutic effect of antacids
neratinib: they may diminish the serum concentration of antacids
nilotinib: they may diminish the serum concentration of antacids
pazopanib: they may diminish the serum concentration of antacids
pexidartinib: they may diminish the serum concentration of antacids
potassium phosphate: they may diminish the serum concentration of antacids
rilpivirine: they may diminish the serum concentration of antacids
riociguat: they may diminish the serum concentration of antacids
selpercatinib: they may diminish the serum concentration of antacids
sotalol: they may diminish the serum concentration of antacids
sotorasib: they may diminish the serum concentration of antacids
sparsentan: they may diminish the serum concentration of antacids
sulpiride: they may diminish the serum concentration of antacids
velpatasvir: they may diminish the serum concentration of antacids
ciprofloxacin inhaled (Pending FDA approval)Â
may diminish the absorption of Quinolones
Alpha-Lipoic Acid: they may diminish the absorption of antacids
bisacodyl rectal: they may decrease the therapeutic effect of antacids
bismuth subgallate: they may decrease the therapeutic effect of antacids
bictegravir: they may decrease the therapeutic effect of antacids
cabotegravir: they may diminish the absorption of antacids
cefdinir: they may diminish the absorption of antacids
deferiprone: they may diminish the serum concentration of antacids
elvitegravir: they may diminish the serum concentration of antacids
erdafitinib: they may diminish the serum concentration of antacids
tetracyclins: they may diminish the serum concentration of antacids
may decrease the therapeutic effect of each other when combined
antacids decrease the concentration of cefditoren in serum
antacids decrease the systemic absorption of naproxen
they decrease the absorption of naproxen
cefditoren: they may diminish the serum concentration of antacids
levonorgestrel: they may diminish the serum concentration of antacids
misoprostol: they may increase the toxic effect of antacids
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
may decrease the effects of the drug by GI absorption inhibition
antacids may decrease the absorption of quinolones
antacids may decrease the absorption of quinolones
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids reduce the systemic absorption of phenothiazine derivatives
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
antacids may reduce the absorption of antipsychotic agents
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
antacids may reduce the serum concentration of multivitamins
antacids may reduce the serum concentration of minerals
may reduce the bioavailability of corticosteroids
may reduce the bioavailability of corticosteroids
may reduce the bioavailability of corticosteroids
may reduce the bioavailability of corticosteroids
may reduce the bioavailability of corticosteroids
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the absorption of antipsychotic agents
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the bioavailability
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
antacids: they may decrease the therapeutic effect of laxative
antacids: they may decrease the therapeutic effect of laxative
antacids: they may decrease the therapeutic effect of laxative
antacids: they may decrease the therapeutic effect of laxative
sodium picosulfate, citric acid, and magnesium oxide
antacids: they may decrease the therapeutic effect of laxative
may enhance the absorption of each other when combined
may enhance the absorption of each other when combined
antacids reduce the systemic absorption of bromeperidol
antacids reduce the concentration of captopril in serum
antacids reduces the systemic absorption of diacerein
antacids reduce the systemic absorption of isoniazid
antacids reduce the concentration of octreotide in the serum
antacids reduce the excretion of quinidine
antacids reduce the concentration of rosuvastatin in the serum
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may decrease the absorption of iron preparations
may diminish the excretion of amphetamines
antacids decrease the efficacy of cysteamine
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
tetraferric tricitrate decahydrate
may decrease the serum concentration
may decrease the serum concentration
bromeperidol: they may decrease the absorption of antacids:
captopril: they may diminish the serum concentration of antacids
cefpodoxime: they may diminish the serum concentration of antacids
octreotide: they may diminish the serum concentration of antacids
rosuvastatin: they may diminish the serum concentration of antacids
antacids can reduce the absorption of diacerein
calcium polystyrene sulfonateÂ
calcium polystyrene sulfonate: they may increase the toxic effect of antacids
isoniazid: they may diminish the absorption of antacids
dried ferrous sulfate/folic acidÂ
reduces the gastrointestinal absorption of iron
they decrease the concentration of active metabolites of infigratinib in the serum
Actions and Spectrum:Â
magaldrate is an aluminum and magnesium-containing compound. It works as an antacid by neutralizing gastric acid in the stomach. When magaldrate comes into contact with stomach acid (hydrochloric acid), it reacts with the acid to form aluminum chloride, magnesium chloride, and water.
This reaction effectively raises the pH of the stomach, reducing the acidity and preventing further irritation of the esophagus and stomach lining. The aluminum and magnesium ions released during this reaction also form a protective layer on the surface of the gastric mucosa, providing a physical barrier against acid damage and promoting healing of any existing lesions caused by hyperacidity.Â
magaldrate’s spectrum of activity is limited to the neutralization of excess stomach acid. It is used primarily to alleviate symptoms associated with hyperacidity, such as heartburn, acid indigestion, and upset stomach. It is not effective against other conditions or infections.Â
Frequency not definedÂ
Stomach painÂ
Loss of appetiteÂ
Painful urinationÂ
Mood changesÂ
NauseaÂ
ConstipationÂ
Swelling in the hands and feetÂ
Black box warning:Â
NoneÂ
Contraindications/caution:Â
Contraindications:Â
Caution:Â
Pregnancy consideration: If the advantages outweigh the hazards, use magaldrate during pregnancy with caution. Animal studies demonstrate risk, but human studies are either not accessible or have not been conducted.Â
Lactation: Excretion of the drug in human breast milk is unknownÂ
Pregnancy category:Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this categoryÂ
Pharmacology:Â
The pharmacology of magaldrate involves its actions as an antacid medication used to neutralize excess stomach acid and relieve symptoms of hyperacidity, heartburn, acid indigestion, and upset stomach. Â
Pharmacokinetics:Â
AbsorptionÂ
magaldrate is administered orally as an antacid and acts locally in the gastrointestinal tract to neutralize stomach acid. It is not significantly absorbed into the bloodstream after oral administration. Instead, most magaldrate remains in the gastrointestinal tract, exerting its local antacid effect.Â
DistributionÂ
As magaldrate is not systemically absorbed, it does not distribute widely throughout the body. Its actions are limited to the administration site, mainly in the stomach and upper part of the gastrointestinal tract.Â
MetabolismÂ
magaldrate is not significantly metabolized in the body. magaldrate’s aluminum and magnesium compounds react with gastric acid to form aluminum chloride, magnesium chloride, and water. These by-products do not undergo extensive metabolism in the body.Â
Elimination and ExcretionÂ
Since magaldrate is not absorbed into the bloodstream, it is not excreted through the kidneys or other elimination pathways as intact drug molecules. Instead, the majority of magaldrate and its by-products are eliminated through feces.Â
Administration:Â
Oral administrationÂ
For suspensions, shake the bottle well before use to ensure proper medication mixing. The dose can be measured using a provided measuring device or spoon. Always use the appropriate measuring device to ensure accurate dosing.Â
Patient information leafletÂ
Generic Name: magaldrateÂ
Why do we use magaldrate?Â
magaldrate is an antacid medication that relieves symptoms associated with hyperacidity and acid-related conditions. The common uses of magaldrate include:Â
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
