Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
No Data Available.
Synonyms :
nabilone
Class :
Antiemetic agents
Brand Name :
No Data Available.
Synonyms :
nabilone
Class :
Antiemetic agents
Dosage forms & StrengthsÂ
Schedule II CapsuleÂ
1mgÂ
Chemotherapy Induced Vomiting And NauseaÂ
1 to 2 mg of nabilone, orally every 8 to 12 hours, is indicated for nausea/vomiting induced after chemotherapy
Not more than 6 mg per day should be administered
Renal impairment
No dose adjustment is required
Chemotherapy Induced Vomiting And NauseaÂ
For nausea/vomiting due to chemotherapy in pediatric patients, more than 4 years
Less than 18 kg of body weight: 0.5 mg orally every 12 hours
18-30 kg of body weight: 1 mg orally every 12 hours
More than 30 kg of body weight: 1 mg orally every 8 hours
Dosage forms & StrengthsÂ
Schedule II CapsuleÂ
1mgÂ
Dosage forms & StrengthsÂ
Schedule II CapsuleÂ
1mgÂ
Chemotherapy Induced Vomiting And NauseaÂ
1-2 mg orally every 8-12 hours
Do not exceed the dose of more than 6 mg every 8 hours
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may affect the absorption of drugs when combined
may have an increased effect of a CNS depressant when combined with cannabinoid products
may have an increased effect of a CNS depressant when combined with cannabinoid products
may have an increased effect of a CNS depressant when combined with cannabinoid products
may diminish the concentration of serum when combined with cannabinoid products
may diminish the concentration of serum when combined with cannabinoid products
may diminish the concentration of serum when combined with cannabinoid products
may diminish the concentration of serum when combined with cannabinoid products
may diminish the concentration of serum when combined with cannabinoid products
when used in combination, nabilone and sodium oxybate both increase the effect of each other
when used in combination, nabilone and metoclopramide both increase the effect of each other
when used in combination, nabilone and calcium/magnesium oxybate both increase the effect of each other
CNS depressants increase the efficacy of cannabinoid products
CNS depressants increase the efficacy of cannabinoid products
CNS depressants increase the efficacy of cannabinoid products
nabilone and alprazolam, when used simultaneously, both increase the sedation
nabilone and baclofen, when used simultaneously, both increase the sedation
nabilone and loxapine, when used simultaneously, both increase the sedation
nabilone and oxazepam, when used simultaneously, both increase the sedation
nabilone and risperidone, when used simultaneously, both increase the sedation
nabilone and triprolidine, when used simultaneously, both increase the sedation
nabilone and ziprasidone, when used simultaneously, both increase the sedation
may enhance the tachycardiac effect
may enhance the tachycardiac effect
may enhance the tachycardiac effect
may enhance the tachycardiac effect
may enhance the tachycardiac effect
may enhance the CNS depressant effect of cannabinoid-containing products
may enhance the CNS depressant effect of cannabinoid-containing products
may enhance the CNS depressant effect of cannabinoid-containing products
may enhance the CNS depressant effect of cannabinoid-containing products
may enhance the CNS depressant effect of cannabinoid-containing products
CNS depressants increase the efficacy of cannabinoid-containing products
CNS depressants increase the efficacy of cannabinoid-containing products
CNS depressants increase the efficacy of cannabinoid-containing products
May have an increased serotonergic effect when combined with Serotonergic Agents
may have an increased CNS depressant effect when combined with cannabinoid-containing products
may have an increased CNS depressant effect when combined with cannabinoid-containing products
may have an increased CNS depressant effect when combined with cannabinoid-containing products
may have an increased tachycardic effect when combined with sympathomimetics
may have an increased tachycardic effect when combined with sympathomimetics
may have an increased tachycardic effect when combined with sympathomimetics
may have an increased tachycardic effect when combined with sympathomimetics
may have an increased tachycardic effect when combined with sympathomimetics
anticholinergic agents increase the effect of tachycardia of cannabinoid-containing products
anticholinergic agents increase the effect of tachycardia of cannabinoid-containing products
anticholinergic agents increase the effect of tachycardia of cannabinoid-containing products
anticholinergic agents increase the effect of tachycardia of cannabinoid-containing products
anticholinergic agents increase the effect of tachycardia of cannabinoid-containing products
may decrease the serum concentration when combined with CYP1A2 substrates
may decrease the serum concentration when combined with CYP1A2 substrates
may decrease the serum concentration when combined with CYP1A2 substrates
may decrease the serum concentration when combined with CYP1A2 substrates
may decrease the serum concentration when combined with CYP1A2 substrates
anticholinergic agents increase the effect of cannabinoid products
anticholinergic agents increase the effect of cannabinoid products
anticholinergic agents increase the effect of cannabinoid products
anticholinergic agents increase the effect of cannabinoid products
anticholinergic agents increase the effect of cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
cannabinoid receptor agonists: they may enhance the serum concentration of CYP3A4 inducers
cannabinoid receptor agonists: they may enhance the serum concentration of CYP3A4 inducers
cannabinoid receptor agonists: they may enhance the serum concentration of CYP3A4 inducers
cannabinoid receptor agonists: they may enhance the serum concentration of CYP3A4 inducers
cannabinoid receptor agonists: they may enhance the serum concentration of CYP3A4 inducers
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may decrease the level of serum concentration
may decrease the level of serum concentration
CNS depressants may enhance the CNS depressant effect of cannabinoid-Containing products
CNS depressants may enhance the CNS depressant effect of cannabinoid-Containing products
CNS depressants may enhance the CNS depressant effect of cannabinoid-Containing products
CNS depressants may enhance the CNS depressant effect of cannabinoid-Containing products
CNS depressants may enhance the CNS depressant effect of cannabinoid-Containing products
may increase the CNS depressant effect of cannabinoid-containing products
may increase the CNS depressant effect of cannabinoid-containing products
may increase the CNS depressant effect of cannabinoid-containing products
may increase the CNS depressant effect of cannabinoid-containing products
may increase the CNS depressant effect of cannabinoid-containing products
may increase the CNS depressant effect of CNS depressants
may increase the tachycardiac effect of sympathomimetics
may have an increased CNS depressive effect when combined with cannabinoid-containing products
may have an increased CNS depressive effect when combined with cannabinoid-containing products
may have an increased CNS depressive effect when combined with cannabinoid-containing products
may increase the toxic effect of CNS muscle relaxants
may increase the anticholinergic effect of anticholinergic agents
may increase the CNS depressant effect of CNS depressants
may increase the CNS depressant effect of CNS depressants
promethazine/dextromethorphanÂ
may increase the CNS depressant effect of CNS Depressants
may increase the CNS depressant effect of CNS Depressants
may increase the tachycardic effect of Anticholinergic Agents
may increase the tachycardic effect
may increase the tachycardic effect
may increase the tachycardic effect
may increase the tachycardic effect
may increase the tachycardic effect
May enhance the tachycardic effect
May enhance the tachycardic effect
May enhance the tachycardic effect
May enhance the tachycardic effect
May enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may enhance the tachycardic effect
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid products
may have an increased effect of CNS depressant when combined with cannabinoid products
may have an increased effect of CNS depressant when combined with cannabinoid products
may have an increased effect of CNS depressant when combined with cannabinoid products
may have an increased tachycardic effect when combined with cannabinoid-containing products
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may have an increasingly adverse effect when combined with cannabis
may have an increased adverse effect when combined with cannabis
may have an increased adverse effect when combined with cannabis
may diminish the concentration of serum when combined with cannabis
may diminish the concentration of serum when combined with cannabis
when used in combination, nabilone and benazepril both increase the effect of each other
when used in combination, nabilone and captopril both increase the effect of each other
nabilone and eucalyptus, when used simultaneously, both increase the sedation
nabilone and sage, when used simultaneously, both increase the sedation
Actions and Spectrum:Â
nabilone acts on the body’s endocannabinoid system, which regulates various physiological processes, including pain, mood, appetite, and immune function. Specifically, it acts as a partial agonist at the CB1 and CB2 receptors located throughout the body and brain. The spectrum of nabilone’s effects includes:Â
Frequency definedÂ
>10%Â
Vertigo Â
Drowsiness Â
Dry mouth Â
Ataxia Â
Visual disturbance Â
Blurred vision Â
Concentration difficulties Â
Euphoria Â
Sleep disturbance Â
1-10%Â
DepersonalizationÂ
DisorientationÂ
DysphoriaÂ
HeadacheÂ
HypotensionÂ
NauseaÂ
There is no Black Box Warning for this drugÂ
Contraindication/Caution:Â
nabilone is a medication that can have potentially serious side effects, and there are certain situations where it should not be used or used with caution. Some of the contraindications and precautions for nabilone include:Â
Pregnancy consideration:Â Â
nabilone should be used in pregnant females only if the potential benefits outweigh the risksÂ
Breastfeeding warnings: Lactating females should not breastfeed during the treatment.Â
Pregnancy category:Â
Pharmacology:Â
The pharmacological effects of nabilone include:Â
Pharmacodynamics:Â
The pharmacodynamics of nabilone refers to the drug’s mechanism of action and its effects on the body. As a synthetic cannabinoid, nabilone acts as a partial agonist at both the CB1 and CB2 receptors located throughout the body and brain.Â
The CB1 receptors are primarily found in the brain and are responsible for regulating various physiological processes, including pain perception, mood, appetite, and memory. The CB2 receptors are primarily found in the immune system, and they are involved in regulating inflammation and immune response.Â
Pharmacokinetics:Â
AbsorptionÂ
The onset of action is within 60-90 minutesÂ
The peak plasma concentration is achieved in 2 hoursÂ
Distribution Â
The volume of distribution is 12.5 L/kgÂ
MetabolismÂ
The drug is metabolized by direct enzymatic oxidation and maybe CYP450 enzymesÂ
Elimination and ExcretionÂ
The drug is excreted 65% in feces (primarily by bile), and 20% in urine Â
The half-life of the parent compound is 2 hours, and of metabolites is 35 hoursÂ
Administration:Â
nabilone is typically administered orally in the form of capsules. The patient should take the capsules with a glass of water and adjust the dose based on the patient’s response to the medication.Â
The recommended starting dose of nabilone for chemotherapy-induced nausea and vomiting is 1 mg, taken 1-3 hours before chemotherapy and repeated every 2-4 hours as needed. The maximum daily dose should not exceed 6 mg.Â
For chronic pain management, the recommended starting dose of nabilone is 0.25-0.5 mg twice daily, and the dosage can be gradually increased as needed. The maximum daily dose should not exceed 2 mg.Â
nabilone should be used cautiously in patients with liver disease, as it is metabolized in the liver. The medication should also be used cautiously in patients taking other medications that can cause CNS depression, such as opioids or benzodiazepines.Â
It is essential to follow the dosage and administration instructions provided by the healthcare professional and report any side effects or adverse reactions that may occur while taking nabilone.Â
Patient information leafletÂ
Generic Name: nabiloneÂ
Pronounced: nah-bi-loneÂ
Why do we use nabilone?Â
nabilone is used for several medical purposes, including:Â
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