A Game-Changer for Diabetes: Polymer Delivers Insulin Painlessly Through Skin
November 25, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Gewodin, Gewolen
Synonyms :
famprofazone
Class :
NSAIDs, analgesic; antipyretic
Brand Name :
Gewodin, Gewolen
Synonyms :
famprofazone
Class :
NSAIDs, analgesic; antipyretic
Dosage Forms & StrengthsÂ
tablets/capsulesÂ
25 mgÂ
100 mgÂ
200 mgÂ
100 mg - 200 mg taken orally twice or thrice a day
Safety and efficacy not establishedÂ
Refer to the adult dosing regimenÂ
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
they decrease the effect of analgesia of opioid agonists
they decrease the effect of analgesia of opioid agonists
may increase the hypertensive effect
MAO inhibitors increase the effect of hypertension of amphetamines
MAO inhibitors increase the effect of hypertension of amphetamines
MAO inhibitors increase the effect of hypertension of amphetamines
MAO inhibitors increase the effect of hypertension of amphetamines
MAO inhibitors increase the effect of hypertension of amphetamines
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
may decrease the therapeutic effect when combined with iobenguane radiopharmaceutical products
may increase the hypertensive effect
may increase the hypertensive effect
may increase the hypertensive effect
may increase the hypertensive effect
may increase the hypertensive effect
may increase the hypertensive effect
may increase the hypertensive effect
may increase the hypertensive effect
may increase the hypertensive effect
may have an increased hypertensive effect when combined with amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
they increase the effect of analgesia of opioid agonists
they increase the effect of analgesia of opioid agonists
may reduce the effect of antihypertensive drugs
may reduce the effect of antihypertensive drugs
may reduce the effect of antihypertensive drugs
may reduce the effect of antihypertensive drugs
may reduce the effect of antihypertensive drugs
may reduce the effect of antihypertensive drugs
may reduce the effect of antihypertensive drugs
may enhance the toxic effect of quinolones
may enhance the toxic effect of quinolones
may enhance the effect of SSRI
may enhance the effect of SSRI
may enhance the effect of SSRI
may enhance the effect of SSRI
may enhance the effect of SSRI
may enhance the effect of SSRI's
may enhance the effect of SSRI's
may enhance the effect of SSRI's
may enhance the effect of SSRI's
may enhance the effect of SSRI's
may enhance the effect of Serotonergic Agents
may increase the analgesic effect of opioid agonists
may increase the analgesic effect of opioid agonists
may increase the analgesic effect of opioid agonists
may increase the analgesic effect of opioid agonists
they decrease the effect of hypertension of antihypertensive agents
they decrease the effect of hypertension of angiotensin II
they decrease the effect of hypertension of angiotensin II
they decrease the effect of hypertension of angiotensin II
they decrease the effect of hypertension of angiotensin II
they decrease the effect of hypertension of angiotensin II
they decrease the effect of hypertension of angiotensin II
they decrease the effect of hypertension of angiotensin II
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids reduce the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
antacids may decrease the excretion of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may enhance the adverse/toxic effect of amphetamines
may increase the analgesic effect of opioids
may decrease the hypertensive effect of anti-hypertensive agents
lisinopril/hydrochlorothiazideÂ
may decrease the anti-hypertensive effect of anti-hypertensive agents
may increase the adverse effect of amphetamines
may increase the adverse effect of amphetamines
may increase the adverse effect of amphetamines
may increase the adverse effect of amphetamines
may increase the adverse effect of amphetamines
may increase the toxic effect of antipsychotic agents
may increase the toxic effect of antipsychotics
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may increase the levels of serum concentration of amphetamines
may increase the levels of serum concentration of amphetamines
may increase the levels of serum concentration of amphetamines
may increase the levels of serum concentration of amphetamines
may increase the levels of serum concentration of amphetamines
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
may enhance the risk of adverse effect of amphetamines
May reduce the levels of serum concentration of amphetamines
May reduce the levels of serum concentration of amphetamines
May reduce the levels of serum concentration of amphetamines
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the analgesic effect of Opioid Agonists
may increase the risk of adverse effect of amphetamines
may increase the risk of adverse effect of amphetamines
may increase the risk of adverse effect of amphetamines
may increase the risk of adverse effect of amphetamines
may increase the risk of adverse effect of amphetamines
ciprofloxacin inhaled (Pending FDA approval)Â
may increase the cardiotoxic effect of Quinolones
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may have an increased analgesic effect when combined with opioid agonists
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
may have an increasingly adverse effect when combined with amphetamines
Actions and spectrum:Â
Actions of famprofazone:Â
Spectrum of famprofazone:Â
famprofazone’s spectrum of action is like other NSAIDs, but it is less potent compared to some other commonly used NSAIDs. It was used to manage various painful conditions, such as musculoskeletal disorders, rheumatic conditions, and post-traumatic pain. However, it is essential to note that famprofazone has been associated with a higher risk of severe adverse effects, including serious skin reactions and haematological disorders. Due to these safety concerns, its use has been restricted or discontinued in many countries.Â
Frequency not definedÂ
gastrointestinal bleedingÂ
stomach painÂ
rashesÂ
Stevens-Johnson syndromeÂ
ThrombocytopeniaÂ
dizziness Â
confusion Â
drowsiness Â
headaches Â
heart attack Â
stroke Â
hepatitis Â
itching Â
difficulty breathing Â
swellingÂ
Black Box Warning:Â
famprofazone carries a black box warning due to its potential for causing severe adverse effects, including serious skin reactions and haematological disorders.Â
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Comorbidities:Â
Pregnancy consideration: pregnancy category: not assignedÂ
Lactation: excreted into breast milk: yes Â
Pregnancy category:Â
Pharmacology:Â
famprofazone is a non-steroidal anti-inflammatory drug (NSAID) that was previously used as an analgesic and anti-inflammatory medication. However, its use has been discontinued or is not widely available in many countries due to safety concerns. The pharmacology of famprofazone is like other NSAIDs and involves the inhibition of the enzyme cyclooxygenase (COX).
COX is responsible for the synthesis of prostaglandins, which are inflammatory mediators that cause pain, inflammation, and fever. By inhibiting COX, famprofazone reduces the production of prostaglandins, thereby providing pain relief and reducing inflammation. Â
Pharmacodynamics:Â
Pharmacokinetics:Â
AbsorptionÂ
famprofazone is absorbed after oral administration, but its absorption may be affected by factors such as food intake and individual variations in gastrointestinal function.Â
DistributionÂ
Once absorbed, famprofazone would distribute throughout the body, including inflamed tissues, where it exerts its anti-inflammatory effects.Â
MetabolismÂ
famprofazone undergoes hepatic metabolism, where it is broken down into various metabolites. The metabolic pathways and enzymes involved in its metabolism may vary among individuals.Â
Elimination and excretionÂ
The elimination of famprofazone and its metabolites primarily occurs through the urine, with a smaller portion being excreted in the feces.Â
Administration:Â
famprofazone has been discontinued or is not widely available in many countries due to safety concerns. Therefore, its administration is no longer recommended or practiced.
famprofazone was an NSAID that was previously used as an analgesic and anti-inflammatory medication, but its use has been restricted or discontinued due to reports of severe adverse effects, including serious skin reactions and haematological disorders.Â
Patient information leafletÂ
Generic Name: famprofazoneÂ
Pronounced: (fam-PRO-fa-zohn)Â Â
Why do we use famprofazone?Â
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
