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Brand Name :
Divascol
Synonyms :
tolazoline, tolazolin, tolazolina,
Class :
Adrenergic Agents, Antihypertensive Agents, Vasodilating Agents
Brand Name :
Divascol
Synonyms :
tolazoline, tolazolin, tolazolina,
Class :
Adrenergic Agents, Antihypertensive Agents, Vasodilating Agents
Dosage Forms & Strengths
Injectable Solution
100 mg/ml
No data available
Refer adult dosing
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
may have an increased bradycardic effect when combined with ceritinib
may have an increased bradycardic effect when combined with ponesimod
may have an increased bradycardic effect when combined with siponimod
may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
may increase the hypotensive effect of anti-hypertensive agents
may increase the serum concentration of each other when it is combined
may increase the serum concentration of each other when it is combined
may increase the serum concentration of each other when it is combined
may increase the serum concentration of each other when it is combined
betony along with antihypertensive drugs can lower blood pressure abruptly which is contraindicated
bloodroot along with antihypertensive medications will result in amplified hypotensive effect
they increase the efficacy of hypotension-associated agents
they increase the efficacy of hypotension-associated agents
they increase the efficacy of hypotension-associated agents
they increase the efficacy of hypotension-associated agents
they increase the efficacy of hypotension-associated agents
it decreases the efficacy of blood pressure-lowering agents
may have an increased arrhythmogenic effect when combined with fexinidazole
may increase the hypertensive effect when combined with androgens
may have an increased vasoconstricting effect when combined with alpha1-agonists
may have an increased vasoconstricting effect when combined with alpha1-agonists
may have an increased vasoconstricting effect when combined with alpha1-agonists
may have an increased vasoconstricting effect when combined with alpha1-agonists
may have an increased vasoconstricting effect when combined with alpha1-agonists
may have an increased hypertensive effect when combined with alpha1-agonists
may have an increased hypertensive effect when combined with alpha1-agonists
may have an increased hypertensive effect when combined with alpha1-agonists
may have an increased hypertensive effect when combined with alpha1-agonists
may have an increased hypertensive effect when combined with alpha1-agonists
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may reduce the vasoconstriction-inducing action
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may enhance the hyperkalemic effect
may enhance the hyperkalemic effect
may enhance the hyperkalemic effect
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may decrease the vasoconstricting effect when combined with alpha1-agonists
bunazosin (Not available in the United States)
may decrease the vasoconstricting effect when combined with alpha1-agonists
may decrease the vasoconstricting effect when combined with alpha1-agonists
may decrease the vasoconstricting effect when combined with alpha1-agonists
may decrease the vasoconstricting effect when combined with alpha1-agonists
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may decrease the antihypertensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
relugolix/​estradiol/​norethindrone
may have an increased hypertensive effect when combined with androgens
relugolix/estradiol/norethindrone
may have an increased hypertensive effect when combined with androgens
may have an increased hypertensive effect when combined with androgens
may have an increased hypertensive effect when combined with androgens
may have an increased hypertensive effect when combined with androgens
may decrease the vasoconstricting effect when combined with alpha1-agonists
may have an increased hypotensive effect when combined with antipsychotic agents
may increase the hypotensive effect of barbiturates
may increase the hypotensive effect of barbiturates
may increase the hypotensive effect of barbiturates
may increase the hypotensive effect of barbiturates
may increase the hypotensive effect of barbiturates
may increase the hypotensive effect of anti-parkinsonism drugs
may increase the hypotensive effect of anti-parkinsonism drugs
may increase the hypotensive effect of anti-parkinsonism drugs
may increase the hypotensive effect of anti-parkinsonism drugs
may increase the hypotensive effect of anti-parkinsonism drugs
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
alpha-1 blocker: they may increase the therapeutic effect of acetylcholine inhibitors
alpha-1 blocker: they may increase the therapeutic effect of acetylcholine inhibitors
buflomedil may lessen tolazoline's antihypertensive effects
It may increase the hypertensive effect when combined with hypertension associated drugs
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
They may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
It may increase the hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive drugs
may have an increased hypotensive effect when combined with antihypertensive drugs
may have an increased hypotensive effect when combined with antihypertensive drugs
relugolix/​estradiol/​norethindrone
they increase the effect of androgens
relugolix/estradiol/norethindrone
they increase the effect of androgens
they increase the effect of androgens
they increase the effect of androgens
they increase the effect of androgens
antihypertensive drugs may make terazosin's hypotensive effects worse
may decrease the antihypertensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with duloxetine
may have an increased bradycardic effect when combined with ivabradine
they decrease the effect of hypertension of antihypertensive agents
they decrease the effect of hypertension of antihypertensive agents
they decrease the effect of hypertension of antihypertensive agents
they decrease the effect of hypertension of antihypertensive agents
they decrease the effect of hypertension of antihypertensive agents
brigatinib: they may decrease the antihypertensive effect when combined with antihypertensive drugs
dexmethylphenidate: they may decrease the therapeutic effect when combined with antihypertensive drugs
flunarizine: they may increase the therapeutic effect when combined with antihypertensive drugs
indoramin: they may increase the hypotensive effect when combined with antihypertensive drugs
loop diuretics: they may increase the hypotensive effect when combined with antihypertensive drugs
loop diuretics: they may increase the hypotensive effect when combined with antihypertensive drugs
loop diuretics: they may increase the hypotensive effect when combined with antihypertensive drugs
methylphenidate: they may decrease the antihypertensive effect when combined with antihypertensive drugs
prazosin: they may increase the hypotensive effect when combined with antihypertensive agents
may increase the hypotensive effect of Phosphodiesterase 5 Inhibitors
may increase the hypotensive effect of Hypotension-Associated Agents
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the hypotensive effect of Blood Pressure Lowering Agents
it increases the effect of BP-lowering agents
it increases the toxicity of calcium channel blockers cabergoline
may have an increased hypotensive effect when combined with anti-hypertensive agents
oxaceprol decreases the effect of anti-hypertensives
may have an increased hypotensive effect when combined with anti-hypertensive agents
may have an increased hypotensive effect when combined with anti-hypertensive agents
may have an increased hypotensive effect when combined with anti-hypertensive agents
may have an increased hypotensive effect when combined with anti-hypertensive agents
molsidomine: they may decrease the antihypertensive effect of antihypertensive agents
naftopidil: they may decrease the antihypertensive effect of antihypertensive agents
nicergoline: they may decrease the antihypertensive effect of antihypertensive agents
hydralazine: they may decrease the antihypertensive effect of antihypertensive agents
pentoxifylline: they may increase the hypotensive effect of antihypertensive agents
pholcodine: they may increase the hypotensive effect of antihypertensive agents
may increase the hypotensive effect of blood pressure lowering agents
may increase the hypotensive effect of blood pressure lowering agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of hypotensive agents
may increase the hypotensive effect of hypotensive agents
may increase the hypotensive effect of hypotensive agents
may increase the hypotensive effect of hypotensive agents
may increase the hypotensive effect of hypotensive agents
quinagolide: they may increase the hypotensive effect of antihypertensive agents
silodosin: they may increase the hypotensive effect of antihypertensive agents
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may have an increased hypotensive effect when combined with anti-hypertensive agents
may have an increased hypotensive effect when combined with anti-hypertensive agents
may have an increased hypotensive effect when combined with anti-hypertensive agents
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may increase the hypotensive effect of alpha1-blockers
may increase the hypotensive effect of alpha1-blockers
may increase the hypotensive effect of alpha1-blockers
may increase the hypotensive effect of alpha1-blockers
may increase the hypotensive effect of alpha1-blockers
may have an increased orthostatic hypotensive effect when combined with alpha1-blockers
may decrease the vasoconstricting effect when combined with alpha1-agonists
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antihypertensive agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
may have an increased hypotensive effect when combined with antipsychotic agents
an increased risk of hypotension may be seen
moxonidine: it may decrease activities of antihypertensive drugs
ambrisentan: it may decrease activities of antihypertensive drugs
balsalazide: it may decrease activities of antihypertensive drugs
benorilate: it may decrease activities of antihypertensive drugs
benoxaprofen: it may decrease activities of antihypertensive drugs
carvedilol: it may decrease activities of antihypertensive drugs
chlorothiazide: it may decrease activities of antihypertensive drugs
celecoxib: it may decrease activities of antihypertensive drugs
chlorpromazine: it may decrease activities of antihypertensive drugs
amitriptyline: it may decrease activities of antihypertensive drugs
rimiterol: it may decrease activities of antihypertensive drugs
amlodipine: it may decrease activities of antihypertensive drugs
amoxapine: it may decrease activities of antihypertensive drugs
anagrelide: it may decrease activities of antihypertensive drugs
bisoprolol: it may decrease activities of antihypertensive drugs
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
May diminish the effects of indomethacin by pharmacodynamic antagonism
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
may increase the hypotensive effect of antipsychotic agents
they modify the response of glucose or insulin when taken with manidipine
Actions and Spectrum:
tolazoline is a medication that primarily acts as a non-selective alpha-adrenergic antagonist. It has a range of pharmacological actions and affects various receptors in the body. Here are some of its key actions and effects:
Frequency undefined
Hypotension
Tachycardia
Headache
Flushing
none
Pregnancy consideration: Insufficient data available
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A:Â well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D:Â adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Administration:
The administration of tolazoline is typically done under medical supervision, and the dosage and route of administration depend on the specific condition being treated.
Tolazoline can be administered orally, intravenously, or intramuscularly.
Patient information leaflet
Generic Name: tolazoline
Why do we use tolazoline?
tolazoline is used for several medical purposes due to its vasodilatory and alpha-adrenergic blocking properties. Here are some common uses of tolazoline:
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