Long COVID Patterns in the RECOVER-Adult Study
November 21, 2025
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Brand Name :
Edecrin
(United States) [Available]Synonyms :
methazolamide
Class :
Diuretics and Loop
Brand Name :
Edecrin
(United States) [Available]Synonyms :
methazolamide
Class :
Diuretics and Loop
NSAIDs may diminish the diuretic effect of loop diuretics
NSAIDs may diminish the diuretic effect of loop diuretics
NSAIDs may diminish the diuretic effect of loop diuretics
NSAIDs may diminish the diuretic effect of loop diuretics
NSAIDs may diminish the diuretic effect of loop diuretics
may decrease the diuretic effect of loop diuretics
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may enhance the toxic effects of the other by pharmacodynamic synergism
may diminish the excretion when combined with lithium
may diminish the excretion when combined with lithium
may decrease the diuretic effect of nonsteroidal anti-inflammatory agents
arsenic trioxide: they may enhance the hypotensive effect of loop diuretics
may decrease the diuretic effect when combined with loop diuretics
May enhance the toxic effects of the other by pharmacodynamic synergism
may decrease the absorption when combined with thiazide diuretics
may increase the sensitivity to pressor effects
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may enhance the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may increase the hypotensive effect
opioid agonists increase the toxicity of diuretics
opioid agonists increase the toxicity of diuretics
amikacin liposome (oral inhalation)Â
they decrease the nephrotoxicity of liposomal amikacin oral inhalation
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
The administration of Loop Diuretics may intensify the hyponatremic impact of desmopressin
The use of Loop diuretics may increase the QTc-prolonging influence of promazine
may diminish the effects of indomethacin by pharmacodynamic antagonism
Loop Diuretics may increase the hypotensive effect of antihypertensive Agents
Loop Diuretics may increase the hypotensive effect of antihypertensive Agents
Loop Diuretics may increase the hypotensive effect of antihypertensive Agents
Loop Diuretics may increase the hypotensive effect of antihypertensive Agents
Loop Diuretics may increase the hypotensive effect of antihypertensive Agents
loop Diuretics may reduce the neuromuscular blocking effect of neuromuscular-Blocking Agents.
loop Diuretics may reduce the neuromuscular blocking effect of neuromuscular-Blocking Agents.
loop Diuretics may reduce the neuromuscular blocking effect of neuromuscular-Blocking Agents.
loop Diuretics may reduce the neuromuscular blocking effect of neuromuscular-Blocking Agents.
loop Diuretics may reduce the neuromuscular blocking effect of neuromuscular-Blocking Agents.
it increases the hypotensive effect of angiotensin II receptor blockers
it increases the hypotensive effect of angiotensin II receptor blockers
it increases the hypotensive effect of angiotensin II receptor blockers
it increases the hypotensive effect of angiotensin II receptor blockers
it increases the hypotensive effect of angiotensin II receptor blockers
may diminish the diuretic effect of loop diuretics
may diminish the diuretic effect of loop diuretics
may diminish the diuretic effect of loop diuretics
may diminish the diuretic effect of loop diuretics
may diminish the diuretic effect of loop diuretics
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may enhance the effect of neuromuscular-blocking agents
may enhance the hypotensive effect of antihypertensive agents
may enhance the hypotensive effect of antihypertensive agents
may enhance the hypotensive effect of antihypertensive agents
may enhance the hypotensive effect of antihypertensive agents
may enhance the hypotensive effect of antihypertensive agents
loop diuretics may increase the risk of adverse effect of aminoglycosides
loop diuretics may increase the risk of adverse effect of aminoglycosides
loop diuretics may increase the risk of adverse effect of aminoglycosides
loop diuretics may increase the risk of adverse effect of aminoglycosides
loop diuretics may increase the risk of adverse effect of aminoglycosides
may enhance the hypotensive effect of angiotensin II receptor antagonist
may enhance the hypotensive effect of angiotensin II receptor antagonist
may enhance the hypotensive effect of angiotensin II receptor antagonist
may enhance the hypotensive effect of angiotensin II receptor antagonist
may enhance the hypotensive effect of angiotensin II receptor antagonist
may increase the risk of adverse effect of cardiac glycosides
may increase the risk of adverse effect of cardiac glycosides
may increase the risk of adverse effect of cardiac glycosides
may diminish the neuromuscular-blocking effect of neuromuscular blocking agentsÂ
may diminish the neuromuscular-blocking effect of neuromuscular blocking agentsÂ
may diminish the neuromuscular-blocking effect of neuromuscular blocking agentsÂ
may diminish the neuromuscular-blocking effect of neuromuscular blocking agentsÂ
may diminish the neuromuscular-blocking effect of neuromuscular blocking agentsÂ
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
May have an increased nephrotoxic effect when combined with Iodinated Agents
May have an increased nephrotoxic effect when combined with Iodinated Agents
May have an increased nephrotoxic effect when combined with Iodinated Agents
May have an increased nephrotoxic effect when combined with Iodinated Agents
It may enhance the effects when combined with maitake by pharmacodynamic synergism
They may diminish the absorption when combined with bile acid sequestrants
It may enhance toxicity when combined with beclomethasone, inhaled by enhancing elimination
It may diminish the effects when combined with metformin by pharmacodynamic antagonism
loop diuretics: they may increase the hypotensive effect when combined with antihypertensive drugs
loop diuretics: they may increase the hypotensive effect when combined with antihypertensive drugs
loop diuretics: they may increase the hypotensive effect when combined with antihypertensive drugs
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
acetaminophen/dextromethorphan/pseudoephedrine/guaifenesin
it may enhance the risk of nephrotoxicity when combined with Diuretics
brompheniramine, dextromethorphan and phenylephrine
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
it may enhance the risk of nephrotoxicity when combined with Diuretics
may have an increased adverse/toxic effect when combined with aminoglycosides
neomycin/polymyxin B/bacitracin topical
may have an increased adverse/toxic effect when combined with aminoglycosides
may decrease the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased hypotensive effect when combined with ACE inhibitors
may have an increased hypotensive effect when combined with ACE inhibitors
may have an increased hypotensive effect when combined with ACE inhibitors
may have an increased hypotensive effect when combined with ACE inhibitors
may have an increased hypotensive effect when combined with ACE inhibitors
loop diuretics: they may increase the toxic effect of mu-opioid receptor agonists
loop diuretics: they may increase the toxic effect of mu-opioid receptor agonists
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased nephrotoxic effect when combined with sodium phosphates
may have an increased hypotensive effect when combined with ACE inhibitors
may have an increased hypotensive effect when combined with ACE inhibitors
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may increase the hypokalemic effect of beta2-agonists
may increase the adverse/toxic effect of diuretics
may increase the adverse/toxic effect of diuretics
may increase the adverse/toxic effect of diuretics
may increase the adverse/toxic effect of diuretics
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may increase the toxicity of the drug by decreasing the renal clearance
may have an increased hypercalcemic effect when combined with vitamin D analogs
loop Diuretics may increase the hypokalemic effect of dichlorphenamide
it May diminish the therapeutic effect of Loop Diuretics
it May diminish the therapeutic effect of Loop Diuretics
it May diminish the therapeutic effect of Loop Diuretics
it May diminish the therapeutic effect of Loop Diuretics
it May diminish the therapeutic effect of Loop Diuretics
loop Diuretics may enhance the hypokalemic effect of topiramate
may decrease the serum potassium levels
empagliflozin increases the effect of hypotension of loop diuretics
may increase the hypokalemic effect of corticosteroids
loop diuretics may increase the risk of adverse effect of allopurinol
may reduce the rate of absorption of loop diuretics
may reduce the effect of loop diuretics
may reduce the effect of loop diuretics
may reduce the effect of loop diuretics
may reduce the effect of loop diuretics
may reduce the effect of loop diuretics
may increase the hypotensive effect of calcium channel blockers
hydrochlorothiazide/aliskirenÂ
may increase the hypotensive effect of antihypertensive agents
may increase the hypotensive effect of angiotensin receptor II blockers
may increase the hypokalemic effect of beta2 agonists
may increase the hypokalemic effect of beta2 agonists
may diminish the therapeutic effect of salicylates
may increase the adverse/toxic effect of Opioid Agonists
buprenorphine,long-acting injectionÂ
may increase the adverse/toxic effect of Opioid Agonists
may have an increased nephrotoxic effect when combined with iodinated agents
may have an increased nephrotoxic effect when combined with iodinated agents
may have an increased nephrotoxic effect when combined with iodinated agents
may have an increased nephrotoxic effect when combined with iodinated agents
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
polyethylene glycol and electrolytesÂ
They may increase the nephrotoxic effect when combined with polyethylene Glycol-electrolyte Solution
may increase the hypokalemic effect when combined
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
it increases the concentration of thiazide and its diuretics in the serum
diacerein: they may increase the therapeutic effect when combined with diuretics
may increase the hypokalemic effect of Beta2-Agonists
Beta2-Agonists: they may increase the hypokalemic effect of loop diuretics
Beta2-Agonists: they may increase the hypokalemic effect of loop diuretics
Beta2-Agonists: they may increase the hypokalemic effect of loop diuretics
The effectiveness of loop diuretics could be reduced by the presence of probenecid
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
it may enhance the risk of nephrotoxicity when combined with Dopamine agonists
acetaminophen/dextromethorphan/pseudoephedrine/guaifenesin
It may enhance the risk of bleeding when combined with Decongestants
brompheniramine, dextromethorphan and phenylephrine
It may enhance the risk of bleeding when combined with Decongestants
It may enhance the risk of bleeding when combined with Decongestants
it increases the effect of hypokalemia of thiazide and other diuretics
may have an increased hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hypotensive effect when combined with angiotensin-converting enzyme inhibitors
may have an increased hypotensive effect when combined with angiotensin-converting enzyme inhibitors
mu-opioid receptor agonists: they may increase the toxic effect of diuretics
mu-opioid receptor agonists: they may increase the toxic effect of diuretics
mu-opioid receptor agonists: they may increase the toxic effect of loop diuretics
mu-opioid receptor agonists: they may increase the toxic effect of loop diuretics
canagliflozin: they may increase the hypotensive effect of loop diuretics
guanethidine: they may increase the hypotensive effect of loop diuretics
Loop Diuretics have the potential to increase the toxic or harmful impact of levosulpiride
loop diuretics may increase the nephrotoxic effect of cefotiam
The QTc-prolonging effect of bilastine may be enhanced by the concurrent use of loop diuretics
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
neomycin/polymyxin B/bacitracin topical
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
The harmful/toxic effect of aminoglycosides may be intensified by loop diuretics
may increase the nephrotoxic effect of angiotensin ii receptor blockers
may increase the nephrotoxic effect of angiotensin ii receptor blockers
may increase the nephrotoxic effect of angiotensin ii receptor blockers
may increase the nephrotoxic effect of angiotensin ii receptor blockers
may increase the nephrotoxic effect of angiotensin ii receptor blockers
may increase the hypokalemic effect of loop diuretics
may increase the hypokalemic effect of loop diuretics
may increase the hypokalemic effect of loop diuretics
may increase the hypokalemic effect of loop diuretics
may increase the hypokalemic effect of loop diuretics
choline magnesium trisalicylate
may decrease the diuretic effect of loop diuretics
nephrotoxicity associated with cisplatin may be enhanced with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
may have an increased hypokalemic effect when combined with loop diuretics
may increase the nephrotoxic effect of angiotensin ii receptor blockers
may increase the nephrotoxic effect of angiotensin ii receptor blockers
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the hypotensive effect of angiotensin-converting enzyme inhibitors
may increase the adverse/toxic effect of cardiac glycosides
may increase the adverse/toxic effect of cardiac glycosides
may increase the adverse/toxic effect of cardiac glycosides
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may diminish the excretion of thiazide diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may increase the hypokalemic effect when combined with diuretics
may have an increased orthostatic hypotensive effect when combined with thiazide diuretics
loop diuretics have the potential to amplify the QTc-prolonging effect of dofetilide
The serum concentration of foscarnet can be enhanced by the concurrent use of loop diuretics
Adverse drug reactions:  Â
Frequency Not DefinedÂ
Injection site reactionÂ
HyperuricemiaÂ
DizzinessÂ
ConfusionÂ
HeadacheÂ
Nausea/vomitingÂ
AnorexiaÂ
DysphagiaÂ
GoutÂ
HypotensionÂ
hypoglycemiaÂ
HypokalemiaÂ
Electrolyte abnormalitiesÂ
HyperglycemiaÂ
OtotoxicityÂ
TinnitusÂ
PhotosensitivityÂ
Muscle crampsÂ
Â
Pregnancy warnings:    Â
Pregnancy Category: BÂ
Breastfeeding warnings: Â
The release of the drug into the human breastmilk is unknownÂ
Pregnancy Categories:      Â
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first trimester or the later trimester.      Â
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women      Â
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women      Â
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits      Â
Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.      Â
Category N: There is no data available for the drug under this category     Â
Â
Patient Information Leaflet Â
Generic Name: ethacrynic acidÂ
Pronounced: ETH-a-KRIN-ik AS-idÂ
Why do we use ethacrynic acid?Â
ethacrynic acid is a diuretic drug that belongs to the sub-class loop used to treat edema caused by CHF, liver and kidney diseaseÂ
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